Leiomyosarcoma of mandible-a rare case report with review of literature
DOI:
https://doi.org/10.18203/2320-6012.ijrms20243733Keywords:
Right lower alveolus, Leiomyosarcoma, PrimaryAbstract
Sarcomas are rare group of malignant mesenchymal tumors, about 1% of all malignancies in adults, leiomyosarcoma constitute 3-10% of all sarcomas in the head and neck region, of them only 0.64% are in oral and maxillofacial region, hence qualifying to be an extremely rare malignancy due to rarity of smooth muscle in that area. Till date approximately 65 cases from 1950-2011 were identified and 20 cases from 2012 till 2024 (as per google search) have been described. We present a case of 51-year-old female who presented with polypoidal growth in right lower alveolus without any lymph node involvement. On histomorphological features and immunohistochemistry, diagnosis of leiomyosarcoma was confirmed.
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References
Ruka W, Rutkowski M. Soft tissue sarcoma-diagnosis and treatment. Oncol Clin Pract (polish). 2009;5:198-210.
Farman AG. Benign smooth muscle tumours. S Afr Med J. 1975;49:1333-40.
Piattelli A, Artese L. Leiomyosarcoma of the tongue: a case report. J Oral Maxillo Surg. 1995;53:698-701.
Amarapala H, Tilakratne WM. Leiomyosarcoma of oral cavity: report of seven cases and review of literature. Oral Oncology Extra 2006;42:14-7.
Yu-Wei Chiu, Ho-Tai Wu. Primary maxillary leiomyosarcoma- a case report. Taiwan J Oral Maxillofac Surg. 2011; 22:207-15.
Donohue JH, van Heerden JA. Atlas of Surgical Oncology. Cambridge: Blackwell Science, Inc;1995.
T.E. Carmody, H.M. Janney, Leiomyosarcoma of the mandible J Am Dent Assoc. 1944;5:1110-4.
Lo Muzio L, Favia G. Primary intraoral leiomyosarcoma of the tongue: an immunohistochemical study and review of the literature. Oral Oncol. 2000;36(6): 519-24.
Wertheimer-Hatch L, Hatch GF 3rd, et al. Tumors of the oral cavity and pharynx. World J Surg. 2000;24:395-400.
PinheiroJde J, AlvesSde M. Primary leiomyosarcoma of the mandible. A case report Med Oral Patol Oral Cir Bucal. 2007;12:56-9.
Mendonca EF, Martins da Silva. Low grade gingival leiomyosarcoma in a child J Dent Child (Chic). 2008;75:301-5.
Ayad W, Dieckmann J. Leiomyosarcoma of the mandibular canal. Possible differential diagnosis of cystic processes of the mandible Mund Kiefer Gesichtschir. 1998;2:42-3.
Schenberg ME, Sloot weg PJ, Leiomyosarcoma of the oral cavity. Report of four cases and review of literature. J Cranio-Maxillofac Surg. 1993;21(8):342-7.
Yan B, LiY. Primary oral Leiomyosarcoma: a retrospective clinical analysis of 20 cases. Oral Dis. 2010;16(2):198-203.
De Bree R, Van Der Waal I. Management of adult soft tissue sarcomas of the head and neck. Oral Oncol. 2010;46 (11):786-90.
Nikitakis NG, Lopes MA. Oral leiomyosarcoma: Review of the literature and report of two cases with assessment of the prognostic and diagnostic significance of IHC and molecular markers Oral Oncol. 2002;38:201-8.
Dry J, Fletcher M. Leiomyosarcoma of the oral cavity: an unusual topographic subset easily mistaken for non-mesenchymal tumors. Histopathology. 2000;36(3):210-20.
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