Evaluation of risk factors of cardiovascular diseases among patients at RIMS hospital in Ranchi, Jharkhand

Anushil Anand; Deepra Ghosh; Prakash Kumar; Pritam Lenka; Bappa Biswas; Sajalendu Ghosh

doi:10.18203/2320-6012.ijrms20243717

Authors

Anushil Anand Department of Environmental Science, Dr. Shyama Prasad Mukherjee University, Ranchi, Jharkhand, India
Deepra Ghosh Department of Statistics, Fox School of Business, Temple University, Philadelphia, USA
Prakash Kumar Department of Cardiology, Rajendra Institute of Medical Science, Ranchi, Jharkhand, India
Pritam Lenka Department of Zoology, Dr. Shyama Prasad Mukherjee University, Ranchi, Jharkhand, India
Bappa Biswas Department of Zoology, Dr. Shyama Prasad Mukherjee University, Ranchi, Jharkhand, India
Sajalendu Ghosh Department of Zoology, Dr. Shyama Prasad Mukherjee University, Ranchi, Jharkhand, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20243717

Keywords:

CVD, Patients, Lipid parameters, Risk factors, Obesity, Hypertension

Abstract

Background: The substantial death toll and disability caused by the global rise in cardiovascular diseases (CVDs) can be largely reduced by assessing and managing the associated risk factors. The 40-69 years age group is most vulnerable to CVDs, accounting for 45% of all deaths. Data on this context for the state of Jharkhand is lacking and the present study was initiated to bridge the gap.

Methods: Risk assessment of common people and patients of CVD was done following WHO’s STEP-wise approach to the surveillance of chronic disease risk factors (WHO 2001) using a structured questionnaire, measurement of anthropometrical parameters, and biochemical analysis of blood samples.

Results: The incidence of CVD is higher in men than in women (8:2), and common risk factors were abnormal lipid parameters and obesity. Compared to asymptomatic common people not under any treatment, CVD patients not under therapeutic intervention to lower lipid levels had a 48-, 34-, and 17-fold higher chance of having aberrant total cholesterol (TC), low-density lipoprotein (LDL), and cholesterol ratio (CR), respectively. Low serum levels of HDL are 3.37 times more likely to occur in females than males. The majority of female patients develop CVD between the ages of 40 and 69; however, 89% of all patients were in the 30-50-year-old age range.

Conclusions: Males are more prone than females to develop CVD mainly due to deranged lipid profiles; nevertheless, between 40 -69 ages, the occurrence of female (68%) patients outnumbers male (63%) patients mainly due to menopause and related metabolic syndromes.

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References

World Health Organization: WHO. Cardiovascular diseases (CVDs). 2021. Available at: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds). Accessed on 10 May 2024.

Tsao CW, Aday AW, Almarzooq ZI, Alvaro A, Andrea ZB, Marcio SB, et al. Heart Disease and stroke statistics-2022 Update: A report from the American Heart Association. Circulation. 2022;145(8):e153-639.

Rayner M, Allender S, Scarborough P. Cardiovascular disease in Europe. Eur J Cardiovascular Prevention Rehabilitation. 2009;16(2):S43-7.

Fuster V, Kelly BB, editors. Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health. Washington (DC): National Academies Press (US); 2010.

Kumar D, Kumari R, Anwar K. Community-based assessment of risk factors for cardiovascular diseases in a tribal population of Tharus in Bihar, India. J Family Med Primary Care. 2022;11(8):4404-9.

Gupta R, Misra A, Pais P. Correlation of regional cardiovascular disease mortality in India with lifestyle and nutritional factors. Int J Cardiol. 2006;108:291-300.

Shanmukhe A, Gowda BY. Risk Stratification for Detection of Coronary Artery Disease and Effectiveness of Sensitization Programme on Reduction of Risk for Coronary Artery Disease among Adults in Selected Urban Areas of Vijayapur. Indian J Publ Heal Res Development. 2023;14(1):6-13.

Geldsetzer P. The Socio-Demographic Characteristics of Diabetes, Hypertension, and Cardiovascular Disease Risk in India. Harvard University; 2018.

Heart disease risk factors. Available at: https://www.texasheart.org/heart-health/heart-information-center/topics/heart-disease-risk-factors/. Accessed on 2 May 2024.

Global atlas on cardiovascular disease prevention and control. 2011. Available at: https://www.who.int/publications/i/item/9789241564373. Accessed on 27 April 2024.

Illinois Heart Disease and Stroke Prevention Program. Available at: http://www.idph.state.il.us/heartstroke/. Accessed on 18 May 2024.

Sytkowski PA, Kannel WB, D'Agostino RB: Changes in risk factors and the decline in mortality from cardiovascular disease: the Framingham Heart Study. N Eng J Med. 1990;322(23):1635-41.

Kurian S, Manjula VD, Zakariah J: A study on cardiovascular risk factor profile of medical students in a tertiary care hospital of central Kerala. National J Med Res. 2015;5(01):11-7.

Prabhakaran D, Jeemon P, Roy A. Cardiovascular diseases in India: current epidemiology and future directions. Circulation. 2016;133(16):1605-20.

Gupta R, Gupta VP, Prakash H. 25-Year trends in hypertension prevalence, awareness, treatment, and control in an Indian urban population: Jaipur Heart Watch. Indian Heart J. 2018;70(6):10.

Lugun J, Ghosh D, Anand A. Prevalence of CVD risk factors among some tribal and nontribal populations of Jharkhand-A comparative survey. Spatial Spatio-Temporal Epidemiol. 2021;37:10.

Riley L, Guthold R, Cowan M. The World Health Organization STEP wise approach to noncommunicable disease risk-factor surveillance: methods, challenges, and opportunities. Am J Publ Heal. 2016;106(1):74-8.

Hotelling H. Analysis of a complex of statistical variables into principal components. J Educational Psychol. 1933;24(6):417-41.

Tomera JF, Harakal C: Multiple linear regression analysis of blood pressure, hypertrophy, calcium and cadmium in hypertensive and nonhypertensive states. Food Chem Toxicol. 1997;35(7):713-8.

Joshi SR, Anjana RM, Deepa M, Rajendra P, Anil B, Vinay KD, et al. Prevalence of dyslipidemia in urban and rural India: the ICMR-INDIAB study. PloS one. 2014;9(5):10.

Roth GA, Mensah GA, Johnson CO, Giovanni A, Enrico A, Larry MB, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study. J Am College Cardiol. 2020;76(25):2982-3021.

Fuster V, Kelly BB, Vedanthan R. Promoting global cardiovascular health: moving forward. Circulation. 2011;123(15):1671-8.

Din S, Rabbi F. Statistical analysis of risk factors for cardiovascular disease in Malakand division. Pak J Statistics Operation Res. 2006;2(1):49-56.

Wang C, Yuan Y, Zheng M, An P, Miao W, Maoxiang Z, et al. Association of age of onset of hypertension with cardiovascular diseases and mortality. J Am College Cardiol. 2020;75(23):2921-30.

Singh S, Malik R. Prevalence of metabolic syndrome in pre-menopausal and post-menopausal women. J Cardiovascular Dis Res. 2023;14(12):3814-23.

Sharma S, Aggarwal N, Joshi B, Vanita S, Sanjay B. Prevalence of metabolic syndrome in pre-and post-menopausal women: A prospective study from apex institute of North India. J Mid-life Health. 2016;7(4):169-74.

Peters SA, Muntner P. Woodward M. Sex differences in the prevalence of, and trends in, cardiovascular risk factors, treatment, and control in the United States, 2001 to 2016. Circulation. 2019;139(8):1025-35.

Banks E, Welsh J, Joshy G. Comparison of cardiovascular disease risk factors, assessment and management in men and women, including consideration of absolute risk: a nationally representative cross-sectional study. BMJ open. 2020;10(12):10.