Innovative treatments for multiple myeloma in adults who are not candidates for stem transplantation

Authors

  • José S. L. Álvarez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Mariano B. L. Perez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Gerardo G. Santiago Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico https://orcid.org/0009-0009-9135-400X
  • Alejandra A. Castro Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Dariana Z. Malfavón Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Irlanda E. Olivarez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Juan C. D. Velasco Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Melissa F. Torres Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
  • Guillermo A. Gonzalez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico https://orcid.org/0009-0001-8356-9096

DOI:

https://doi.org/10.18203/2320-6012.ijrms20243457

Keywords:

Multiple myeloma, Treatment, Diagnosis, Innovation, Survival

Abstract

In the reviewed article, we evaluated the different innovative therapeutic options for the treatment of multiple myeloma in patients who are not candidates for stem cell transplantation. Multiple myeloma (MM) is a malignant neoplasm whose incidence is increasing in developed countries. It represents around 1% of neoplastic diseases and 13% of hematologic cancers. It arises from an asymptomatic proliferation of premalignant monoclonal plasma cells derived from B cells after they pass through the germinal center stage in various genetic steps and microenvironmental changes. Although in this study we discuss various therapeutic options that seem promising, we must keep in mind that these still require further research for their application in order to reduce the adverse effects that some of them may present.

 

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References

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Published

2024-11-21

How to Cite

Álvarez, J. S. L., Perez, M. B. L., Santiago, G. G., Castro, A. A., Malfavón, D. Z., Olivarez, I. E., Velasco, J. C. D., Torres, M. F., & Gonzalez, G. A. (2024). Innovative treatments for multiple myeloma in adults who are not candidates for stem transplantation. International Journal of Research in Medical Sciences, 12(12), 4767–4776. https://doi.org/10.18203/2320-6012.ijrms20243457

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Section

Review Articles