Corpus callosum hypogenesis with interhemispheric cyst: a case report
Keywords:
Corpus callosum, Agenesis, Interhemispheric cystAbstract
Agenesis or hypogenesis of Corpus callosum with interhemispheric cyst is a rare entity. Origin of interhemispheric cyst is controversial. These cysts may be Arachnoid cyst, neuroepithelial cyst, or extension of lateral or third ventricles. Here we describe a case of Corpus callosal hypogenesis with an interhemispheric cyst. Associated aqueductal stenosis and schizencephaly is also present. Interhemispheric cyst is communicating with lateral ventricle and the cyst has MRI signal intensity similar to CSF. This case supports the theory that the interhemispheric cyst is an ependymal cyst and is consequence of increased intraventricular pressure due to aqueductal stenosis.
References
Kolodny EH, Agenesis of the corpus callosum: a marker for inherited metabolic disease? Neurology. 1989;39:647-8.
Babcock D. The normal, absent and abnormal corpus callosum: sonographic findings. Radiology. 1984;151(2):449-53.
Atlas SW, Zimmerman RA, Bilaniuk LT, Rorke L, Hackney DB, Goldberg HI, et al. Corpus callosum and limbic system: neuroanatomic MR evaluation of developmental anomalies. Radiology. 1986;160:355-62.
Barkovich AJ, Norman D. Anomalies of the corpus callosum: correlation with further anomalies of the brain. Am J Neuroradiol. 1988;9:493-501.
Davila-Gutierrez G. Agenesis and dysgenesis of the corpus callosum. Semin Pediatr Neurol. 2002;9:292-301.
Barkovich AJ. Anomalies of the corpus callosumand cortical malformations. In: Barth PG, eds. Disorders of Neuronal Migration (International Review of Child Neurology). 2nd ed. London, UK: Mac Keith Press; 2003: 83-103.
Barkovich AJ, Simon EM, Walsh CA. Callosal agenesis with cyst: a better understanding and new classification. Neurology. 2001;56:220-7.
A. James Barkovich. Interhemispheric cyst. In: A. James Barkovich, eds. Pediatric Neuroimaging. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2005.
Smith AS, Levine D. Appearance of an interhemispheric cyst associated with agenesis of corpus callosum. AJNR Am J Neuroradiol. 2004;25:1037-40.
Kendall B. Dysgenesis of the corpus callosum. Neuroradiology. 1983;25;239-57.
Ettlinger G. Agenesis of the corpus callosum In: Vinker PBruyn G, eds. Hand Book of Clinical Neurology. 1st ed. Amsterdam, North Holland: Elsevier; 1977: 285-297.
Steven W. Hetts. Anomalies of the corpus callosum: an MR analysis of the phenotypic spectrum of associated malformations. AJR Am J Roentgenol. 2006;187:1343-8.
Bickers DS, Adams RD. Hereditary stenosis of the aqueduct of sylvius as a cause of congenital hydrocephalus. Brain. 1949;72:246-62.