Clinical and etiological findings of musculotendinous injuries after physical exercise

Adonis A. Gavilanez; Juan J. Riofrío; Yesenia L. Rumipamba; Francisca A. Loaiza; Fernanda S. Tipan; Paula A. Vásconez; Erika V. Proaño; Cristhian A. Coral; Bryan A. Villota

doi:10.18203/2320-6012.ijrms20244162

Authors

Adonis A. Gavilanez Ministry of Public Health, Quito, Ecuador
Juan J. Riofrío Ministry of Public Health, Quito, Ecuador
Yesenia L. Rumipamba Ministry of Public Health, Quito, Ecuador
Francisca A. Loaiza Ministry of Public Health, Quito, Ecuador
Fernanda S. Tipan Ministry of Public Health, Quito, Ecuador
Paula A. Vásconez UIDE University, Quito, Ecuador
Erika V. Proaño RIOVASC, Ambato, Ecuador
Cristhian A. Coral I.P.S ARTMEDICA, Medellín, Colombia
Bryan A. Villota PUCE, University, Quito, Ecuador

DOI:

https://doi.org/10.18203/2320-6012.ijrms20244162

Keywords:

Sport muscle injury, Musculofascial injury, Pathogenesis, Stress tendinopathy

Abstract

The pathogenesis of sports injuries is complex and difficult to identify clearly. Recent theories bring to light new mechanisms related to the production of muscle pain and tendinopathies. The accumulation of lactate can cause fatigue and muscle pain. Apparently, the lactate anion is an excellent fuel for myocardial fibre. Its accumulation of lactic acid after performing intense physical exercise can prevent the excitability of the sarcolemma induced by the increase in the concentration of the interstitial potassium ion. The identification of sports and physical activity that can cause damage to our body has become necessary, due to the increase in the incidence of joint injuries generated by physical activity in people who routinely practice exercise and in athletes, in order to prevent future injuries. Articles related to the different mechanisms involved in the different musculoskeletal injuries related to the practice of exercise have been selected.

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References

Prior BM, Yang HT, Terjung RL. What makes vessels grow with exercise training? J Appl Physiol. 2004;97(3):1119–28.

Hotta K, Behnke BJ, Arjmandi B, et al. Daily muscle stretching enhances blood flow, endothelial function, capillarity, vascular volume andconnectivity in aged skeletal muscle. J Physiol. 2018;596(10):1903–17.

Behnke BJ, Ramsey MW, Stabley JN, et al. Effects of aging and exercise training on skeletal muscle blood flow and resistance artery morphology. J Appl Physiol. 2012;113(11):1699–708.

Wilke J, Hespanhol L, Behrens M. Is it all about the fascia? A systematic review and meta-analysis of the prevalence of extramuscular connective tissue lesions in muscle strain injury. Orthop J Sports Med. 2019;7(12):2325967119888500.

Chéron C, Le Scanff C, Leboeuf-Yde C. Association between sports type and overuse injuries of extremities in adults: a systematic review. Chiropr Man Therap. 2017;25:4.

Kunutsor SK, Laukkanen JA. Physical activity, exercise and adverse cardiovascular outcomes in individuals with pre-existing cardiovascular disease: a narrative review. Expert Review of Cardiovascular Therapy. 2024;22:91–101.

Isath A, Koziol KJ, Martinez MW, Garber CE, Martinez MN, Emery MS, et al. Exercise and cardiovascular health: A state-of-the-art review. Prog Cardiovasc Dis. 2023;79:44–52.

Pinckard K, Baskin KK, Stanford KI. Effects of exercise to improve cardiovascular health. Frontiers in Cardiovas Med. 2019;6:69.

Nystoriak MA, Bhatnagar A. Cardiovascular effects and benefits of exercise. Frontiers in Cardiovas Med. 2018;5:408204.

Mannakkara NN, Finocchiaro G. Exercise and the heart: Benefits, risks and adverse effects of exercise training. Reviews in Cardiovascular Medicine. 2023;24(3):94.

Königstein K, Dipla K, Zafeiridis A. Training the vessels: molecular and clinical effects of exercise on vascular health—a narrative review. Cells. 2023;12(21):2544.

Maga M, Wachsmann-Maga A, Batko K, Włodarczyk A, Kłapacz P, et al. Impact of blood-flow-restricted training on arterial functions and angiogenesis—a systematic review with meta-analysis. Biomedicines. 2023;11(6):1601.

Ross M, Kargl CK, Ferguson R, Gavin TP, Hellsten Y. Exercise-induced skeletal muscle angiogenesis: impact of age, sex, angiocrines and cellular mediators. Europ J App Physiol. 2023;123:1415–32.

Amar D, Gay NR, Jimenez-Morales D, Jean Beltran PM, Ramaker ME, et al. The mitochondrial multi-omic response to exercise training across tissues. Available from: https://doi.org. Accessed on 21 August 2024.

Roberts FL, Markby GR. New insights into molecular mechanisms mediating adaptation to exercise; A review focusing on mitochondrial biogenesis, mitochondrial function, mitophagy and autophagy. Cells. 2021;10(10):2639.

Musat CL, Niculet E, Craescu M, Nechita L, Iancu L, Nechita A, et al. Pathogenesis of musculotendinous and fascial injuries after physical exercise-short review. Int J Gen Med. 2023;16:5247–54.

Şenışık SÇ, Akova B, Şekir U, Gür H. Effects of muscle architecture on eccentric exercise induced muscle damage responses. J Sports Sci Med. 2021;20(4):655.

Sunbol KM, Althiyabi FS, Alshuria AA, Alajwad MH, Mahlawi AM, Alsayed BH, et al. Etiology, risk factors and complications of exercise induced muscle injury. Int J Community Med Public Health. 2023;10(1):383–7.

Qian Z, Ping L, Xuelin Z. Re‑examining the mechanism of eccentric exercise‑induced skeletal muscle damage from the role of the third filament, titin (Review). Biomed Rep. 2024;20(1):14.

Wilke J, Hespanhol L, Behrens M. Is it all about the fascia. A systematic review and meta-analysis of the prevalence of extramuscular connective tissue lesions in muscle strain injury. Orthop J Sports Med. 2019;7(12):2325967119888500.

Musat CL, Niculet E, Craescu M, Nechita L, Iancu L, Nechita A, et al. Pathogenesis of musculotendinous and fascial injuries after physical exercise - short review. Int J Gen Med. 2023;16:5247–54.

SantAnna JP, Pedrinelli A, Hernandez AJ, Fernandes TL. Muscle Injury: Pathophysiology, Diagnosis, and Treatment. Rev Bras Ortop. 2022;57(1):1–13.

Huygaerts S, Cos F, Cohen DD, Calleja-González J, Guitart M, Blazevich AJ, et al. Mechanisms of hamstring strain injury: Interactions between fatigue, muscle activation and function. Sports. 2020;8(5):65.

Wan X, Li S, Best TM, Liu H, Li H, Yu B. Effects of flexibility and strength training on peak hamstring musculotendinous strains during sprinting. J Sport Health Sci. 2021;10(2):222-9.

López-Valenciano A, Ruiz-Pérez I, Garcia-Gómez A, Vera-Garcia FJ, De Ste Croix M, Myer GD, et al. Epidemiology of injuries in professional football: A systematic review and meta-analysis. Br J Sports Med. 2020;54(12):711-8.

Musat CL, Niculet E, Craescu M, Nechita L, Iancu L, Nechita A, Voinescu DC, Bobeica C. Pathogenesis of Musculotendinous and Fascial Injuries After Physical Exercise-Short Review. International Journal of General Medicine. 2023 Dec 31:5247-54

Wilke J, Behringer M. Is “delayed onset muscle soreness” a false friend? The potential implication of the fascial connective tissue in post-exercise discomfort. International J Mol Sci. 2021;22(17):9482.

Musat CL, Niculet E, Craescu M, Nechita L, Iancu L, Nechita A, Voinescu DC, Bobeica C. Pathogenesis of Musculotendinous and Fascial Injuries After Physical Exercise-Short Review. Internatil Journal of General Medicine. 2023;21:5247-54.

Musat CL, Niculet E, Craescu M, Nechita L, Iancu L, Nechita A, Voinescu DC, Bobeica C. Pathogenesis of musculotendinous and fascial injuries after physical exercise-short review. Int J Gen Med. 2023;4:5247-54.

Bangsbo J, Hostrup M. Lactate production contributes to development of fatigue during intense exercise in humans. Ugeskrift for laeger. 2019;181(8):10180669.

Fiorenza M, Hostrup M, Gunnarsson TP, Shirai Y, Schena F, Iaia FM, Bangsbo J. Neuromuscular fatigue and metabolism during high-intensity intermittent exercise. Medicine and Sci Sports and Exercise. 2019;51(8):1642-52.