Value of urinary microalbumin test in cancer patients with borderline serum creatinine level

Authors

  • Sawmik Das Department of Biochemistry Section of Pathology, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam
  • Anupam Sarma Department of Pathology, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam
  • Jagannath Dev Sharma Department of Pathology, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam
  • Shiraj Ahmed Department of Pathology, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam
  • Manigreeva Krishnatreya Department of Epidemiology and Biostatistics, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam
  • Amal Chandra Kataki Department of Gynecologic Oncology, Dr. B Borooah Cancer Institute, Guwahati-781016, Assam

Keywords:

Borderline creatinine, Cancer patients, Microalbumin, Urine

Abstract

Background: Micralbuminuria (MA) is an early sign of incipient renal damage and cancer patients are at the risk of developing kidney diseases due to the use of nephrtoxic chemotherapeutic agents.

Methods: A pilot study of urinary microalbumin on 41 patients with borderline serum creatinine was carried out at regional cancer centre of North-East India during the period from June to August 2014. The patients whose serum creatinine levels were between 1.2 mg/dl to 1.3 mg/dl were considered as borderline for the present study. The assays were performed with a dimension Rxl max random access biochemistry analyzer.

Results: Out of 41 cases, 22 (53.6%) had MA, M:F = 1.75, <45 years 3 (13.6%) patients, in 45 years - 65 years 17 (77.2%) patients, and >65 years 2 (9.0%) patients were detected with urinary microalbumin. Chi square test showed P = 0.695 (Fisher’s exact P value).  

Conclusion: Testing of urinary microalbumin can be done in cancer patients with borderline serum creatinine level in order to identify patients at risk of developing kidney disease.  

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Published

2017-01-08

How to Cite

Das, S., Sarma, A., Sharma, J. D., Ahmed, S., Krishnatreya, M., & Kataki, A. C. (2017). Value of urinary microalbumin test in cancer patients with borderline serum creatinine level. International Journal of Research in Medical Sciences, 3(5), 1199–1202. Retrieved from https://www.msjonline.org/index.php/ijrms/article/view/1469

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Original Research Articles