Value of urinary microalbumin test in cancer patients with borderline serum creatinine level

Sawmik Das, Anupam Sarma, Jagannath Dev Sharma, Shiraj Ahmed, Manigreeva Krishnatreya, Amal Chandra Kataki

Abstract


Background: Micralbuminuria (MA) is an early sign of incipient renal damage and cancer patients are at the risk of developing kidney diseases due to the use of nephrtoxic chemotherapeutic agents.

Methods: A pilot study of urinary microalbumin on 41 patients with borderline serum creatinine was carried out at regional cancer centre of North-East India during the period from June to August 2014. The patients whose serum creatinine levels were between 1.2 mg/dl to 1.3 mg/dl were considered as borderline for the present study. The assays were performed with a dimension Rxl max random access biochemistry analyzer.

Results: Out of 41 cases, 22 (53.6%) had MA, M:F = 1.75, <45 years 3 (13.6%) patients, in 45 years - 65 years 17 (77.2%) patients, and >65 years 2 (9.0%) patients were detected with urinary microalbumin. Chi square test showed P = 0.695 (Fisher’s exact P value).  

Conclusion: Testing of urinary microalbumin can be done in cancer patients with borderline serum creatinine level in order to identify patients at risk of developing kidney disease.  


Keywords


Borderline creatinine, Cancer patients, Microalbumin, Urine

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References


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