Pre and post tonsillectomy status of serum antistreptolysin o titre in chronic tonsillitis patients

Pushan Dutta; Nandita Nath; Smrity Rupa Borah Dutta

doi:10.18203/2320-6012.ijrms20250678

Authors

Pushan Dutta Department of Otorhinolaryngology, Silchar Medical College and Hospital, Silchar, Assam, India
Nandita Nath Department of Otorhinolaryngology, Silchar Medical College and Hospital, Silchar, Assam, India
Smrity Rupa Borah Dutta Department of Otorhinolaryngology, Silchar Medical College and Hospital, Silchar, Assam, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20250678

Keywords:

Antistrptolysin O titre, Group A beta hemolytic Streptococcus, Tonsillectomy

Abstract

Background: Tonsillitis is a very common disease, more prevalent in children and can be caused by a variety of microbes, out of which group A beta hemolytic Streptococcus (GABHS) is the most common. GABHS infection leads to elevated ASO titre in patient’s serum which may lead to several systemic complications if left untreated. The aim was to find out the prevalence of elevated ASO titre in patients with chronic tonsillitis and to analyse the impact of doing tonsillectomy in lowering the serum ASO titre.

Methods: A prospective observational study was carried out on 70 patients during a period of 1 year, who were admitted in ENT ward, Silchar Medical College and Hospital and were planned for tonsillectomy. Serum ASO titre was measured pre-operatively and on every follow-up at 1, 3 and 6 months post-operative period.

Results: Out of 70 patients, 26 were positive (37%) for ASO tire pre-operatively. There was not much improvement of ASO titre at 1 month after surgery but 3 months onwards there was significant reduction in ASO-titre level and at 6 months 21 of the 26 (80.7%) patients became negative for serum ASO titre.

Conclusions: In our study, we have found that tonsillectomy in indicated patients with raised ASO-titre has a significant role in reducing the titre level post-operatively and thus it prevents serious complications of streptococcal infections like rheumatic fever, glomerulonephritis etc.

Metrics

Metrics Loading ...

References

Hembrom R, Roychaudhuri BK, Saha AK, Roychowdhury A, Ghosh S, Gon S, et al. Evaluation of the validity of high serum antistreptolysin o titre only, as an indication for tonsillectomy. Indian J Otolaryngol Head Neck Surg. 2014;66(3):232-6. DOI: https://doi.org/10.1007/s12070-012-0579-5

Patel SD, Daher GS, Engle L, Zhu J, Slonimsky G. Adult tonsillectomy: an evaluation of indications and complications. Am J Otolaryngol. 2022;43(3):103403. DOI: https://doi.org/10.1016/j.amjoto.2022.103403

Mitic S, Tvinnereim M, Lie E, Šaltytė BJ. A pilot randomized controlled trial of coblation tonsillectomy versus dissection tonsillectomy with bipolar diathermy haemostasis. Clin Otolaryngol. 2007;32(4):261-7. DOI: https://doi.org/10.1111/j.1365-2273.2007.01468.x

Khan MF, Iqbal J, Raza N, Amjad M. Diode laser tonsillectomy a comparison with conventional technique. Pak J Otolaryngol. 2002;26:30-1.

Curtin JM. The history of tonsil and adenoid surgery. Otolaryngol Clin North Am. 1987;20(2):415-9. DOI: https://doi.org/10.1016/S0030-6665(20)30509-0

Viswanathan N, Nair SS, Thulseedharan S. Effect of tonsillectomy on aso-titre. Indian J Otolaryngol Head Neck Surg. 2000;52(4):329-31. DOI: https://doi.org/10.1007/BF02991470

Read SE, Zabriskie JB, eds. Streptococcal Diseases and the Immune Response, New York, Academic Press; 1980.

Matanoski GM, Price WH, Ferencz C. Epidemiology of streptococcal infections in rheumatic and non rheumatic families. Am J Epidemiol. 1968;87:226. DOI: https://doi.org/10.1093/oxfordjournals.aje.a120803

Paradise JL, Bluestone CD, Bachman RZ, Colborn DK, Bernard BS, Taylor FH, et al. Efficacy of tonsillectomy for recurrent throat infection in severely affected children: results of parallel randomized and nonrandomized clinical trials. N Engl J Med. 1984;310(11):674-83. DOI: https://doi.org/10.1056/NEJM198403153101102