Difference of post COVID health complications among infection and reinfection patients: a comparative study
DOI:
https://doi.org/10.18203/2320-6012.ijrms20250663Keywords:
COVID-19, Infection, Post COVID complications, ReinfectionAbstract
Background: The novel coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus emerged as a global pandemic in December 2019, leading to significant health concerns. As the pandemic progressed, the post-recovery manifestations in survivors became a growing issue. Therefore, this comparative study aimed to assess the post-COVID health complication difference between infection and reinfection patients.
Methods: This cross-sectional study was conducted in the department of project and research, Dhaka Community Medical College Hospital, Dhaka, Bangladesh, from December 2023 to December 2024. In this study, we included 244 patients who got their treatment from Dhaka Community Medical Hospital.
Results: The study found that reinfection patients had higher percentages of complications, with pain reported in 15% of reinfection cases. Weakness was present in 33% of infection patients and 37% of reinfection patients. The mental health complications also seen in respondents like anxiety accounted for 30% of infection respondents and 19% of reinfection respondents. Depression was reported in 12% of infection cases and 7% of reinfection cases. Household factors like gender, BMI, religion, marital status, residence, living conditions, and smoking habits are significantly associated with both infection and reinfection patients.
Conclusions: This study found that the occurrence of post-COVID complications among patients with infection and reinfection was significantly different. Gender, marital status, living conditions, and smoking habits were the significant factors associated with differences in post-COVID complications among patients with infection and reinfection.
Metrics
References
World Health Organization. Coronavirus disease (COVID-19) pandemic. 2020. Available from: https://www.who.int/data/gho/publications/world-health-statistics. Accessed on 25 May 2020.
Bary M, Temsah MH, Al-Sohime F. The psychological impact of COVID-19 pandemic on healthcare workers in a MERS-CoV endemic country. J Infect Public Health. 2020;13:877-82. DOI: https://doi.org/10.1016/j.jiph.2020.05.021
Baig AM. Chronic COVID syndrome: need for an appropriate medical terminology for long-COVID and COVID long-haulers. J Med Virol. 2021;93(5):2555-6. DOI: https://doi.org/10.1002/jmv.26624
Sridhar S, Nicholls J. Pathophysiology of infection with SARS-CoV-2-What is known and what remains a mystery. Respirology. 2021;26:652-65. DOI: https://doi.org/10.1111/resp.14091
Van Damme W, Dahake R, Delamou A, Ingelbeen B, Wouters E, Vanham G, et al. The COVID-19 pandemic: Diverse contexts; different epidemics-how and why? BMJ Glob Health. 2020;5:e003098. DOI: https://doi.org/10.1136/bmjgh-2020-003098
Salamanna F, Veronesi F, Martini L, Landini MP, Fini M. Post-COVID-19 syndrome: the persistent symptoms at the post-viral stage of the disease: a systematic review of the current data. Front Med. 2021;8:653516. DOI: https://doi.org/10.3389/fmed.2021.653516
Cairoli E. What do you mean by COVID-19? Rev Clin Esp. 2021;221:614-6. DOI: https://doi.org/10.1016/j.rceng.2021.07.002
Carod-Artal FJ. Post-COVID-19 syndrome: Epidemiology, diagnostic criteria and pathogenic mechanisms involved. Rev Neurol. 2021;72:384-96. DOI: https://doi.org/10.33588/rn.7211.2021230
Shah W, Hillman T, Playford ED, Hishmeh L. Managing the long-term effects of COVID-19: Summary of NICE, SIGN, and RCGP rapid guideline. BMJ. 2021;372:n136. DOI: https://doi.org/10.1136/bmj.n136
National Institute for Health and Care Excellence. COVID-19 Rapid Guideline: Managing the Long-Term Effects of COVID-19. 2020. Available from: https://www.nice.org.uk/guidance/ng188. Accessed on 12 September 2021.
Greenhalgh T, Knight M, A’Court C, Buxton M, Husain L. Management of post-acute COVID-19 in primary care. BMJ. 2020;370:m3026. DOI: https://doi.org/10.1136/bmj.m3026
Shanbehzadeh S, Tavahomi M, Zanjari N, Ebrahimi-Takamjani I, Amiri-Arimi S. Physical and mental health complications post-COVID-19: Scoping review. J Psychosom Res. 2021;147:110525. DOI: https://doi.org/10.1016/j.jpsychores.2021.110525
Sonnweber T, Sahanic S, Pizzini A, Luger A, Schwabl C, Sonnweber B, et al. Cardiopulmonary recovery after COVID-19: an observational prospective multicentre trial. Eur Respir J. 2021;57:2003481. DOI: https://doi.org/10.1183/13993003.03481-2020
Starace M, Iorizzo M, Sechi A, Alessandrini AM, Carpanese M, Bruni F, et al. Trichodynia and telogen effluvium in COVID-19 patients: Results of an international expert opinion survey on diagnosis and management. JAAD Int. 2021;5:11-8. DOI: https://doi.org/10.1016/j.jdin.2021.07.006
Zarei M, Bose D, Nouri-Vaskeh M, Tajiknia V, Zand R, Ghasemi M. Long-term side effects and lingering symptoms post-COVID-19 recovery. Rev Med Virol. 2021;e2289. DOI: https://doi.org/10.1002/rmv.2289
Sivan M, Taylor S. NICE guideline on long COVID. BMJ. 2020;371:m4938. DOI: https://doi.org/10.1136/bmj.m4938
Carfì A, Bernabei R, Landi F. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324(6):603-5. DOI: https://doi.org/10.1001/jama.2020.12603
Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post‐COVID‐19 manifestations. Int J Clin Pract. 2020;75:e13746. DOI: https://doi.org/10.1111/ijcp.13746
Datta SD, Talwar A, Lee JT. A proposed framework and timeline of the spectrum of disease due to SARS‐CoV‐2 infection: illness beyond acute infection and public health implications. JAMA. 2020;324(22):2251‐2. DOI: https://doi.org/10.1001/jama.2020.22717
Fernández-de-Las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, Cuadrado ML, Florencio LL. Defining post‐COVID symptoms: An integrative classification. Int J Environ Res Public Health. 2021;18(5):2621. DOI: https://doi.org/10.3390/ijerph18052621
Kayaaslan B, Eser F, Kalem AK, Kaya G, Kaplan B, Kacar D, et al. Post‐COVID syndrome: A single‐center questionnaire study on 1007 participants recovered from COVID‐19. J Med Virol. 2021;93(12):6566-74. DOI: https://doi.org/10.1002/jmv.27198
Domènech-Montoliu S, Puig-Barberà J, Pac-Sa MR, Vidal-Utrillas P, Latorre-Poveda M, Del Rio-González A, et al. Complications post-COVID-19 and risk factors among patients after six months of a SARS-CoV-2 infection: a population-based prospective cohort study. Epidemiologia. 2022;3:49-67. DOI: https://doi.org/10.3390/epidemiologia3010006
CDC. Long-Term Effects of COVID-19. 2020. Available from: https://stacks.cdc.gov/ view/cdc/97204. Accessed on 16 January 2021.
Cao W, Fang Z, Hou G, Han M, Xu X, Dong J, et al. The psychological impact of the COVID-19 epidemic on college students in China. Psychiatr Res. 2020;287:112934. DOI: https://doi.org/10.1016/j.psychres.2020.112934
McIntosh K. Coronavirus disease 2019 (COVID-19): clinical features. 2020. Available from: https://www.uptodate.com/contents/search. Accessed on 23 July 2021.
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, et al. Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from COVID-19. JAMA Cardiol. 2020;5:1265-73. DOI: https://doi.org/10.1001/jamacardio.2020.3557
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9. DOI: https://doi.org/10.1001/jama.2020.1585
Khan S, Ali A, Shi H, Siddique R, Shabana, Nabi G, et al. COVID-19: Clinical aspects and therapeutics responses. Saudi Pharm J. 2020;28:1004-8. DOI: https://doi.org/10.1016/j.jsps.2020.06.022