PLA2-R positive primary membranous nephropathy: a case report

Authors

  • Eduardo Abraham Quen Sánchez Department of Internal Medicine, Clinica Hospital Mérida, ISSSTE. Facultad de Medicina, Universidad Autonoma de Yucatán (UADY), Merida, Yucatán, México
  • Carlos Eduardo Ortiz Castañeda
  • Juan Carlos Anaya Zamora Department of Nephrology, Hospital Regional "Dr. Valentín Gómez Farías", ISSSTE. Guadalajara, Jalisco, México
  • Yari Esilde Baeza Hernández Department of Nephrology, Hospital Regional "Dr. Valentín Gómez Farías", ISSSTE. Guadalajara, Jalisco, México
  • José Emmanuel Dzul Caballero Department of Internal Medicine, Clinica Hospital Mérida, ISSSTE. Facultad de Medicina, Universidad Autonoma de Yucatán (UADY), Merida, Yucatán, México

DOI:

https://doi.org/10.18203/2320-6012.ijrms20250267

Keywords:

Membranous nephropathy, PLA2-R receptor, Nephrotic syndrome, Modified ponticelli, Rituximab

Abstract

Membranous nephropathy (MN) is a significant cause of nephrotic syndrome in adults, often linked to the presence of circulating antibodies against phospholipase A2 receptor (PLA2R). This case report details the clinical presentation, diagnostic process, treatment, and outcomes of a patient diagnosed with PLA2R-positive membranous nephropathy. The report highlights the importance of early diagnosis and personalized treatment strategies, demonstrating the evolving landscape of MN management. A brief review of the literature related to the topic is also presented. For this purpose, a search was made in freely accessible sources, selecting those with the most relevant and up-to-date information.

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References

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Published

2025-01-30

How to Cite

Quen Sánchez, E. A., Ortiz Castañeda, C. E., Anaya Zamora, J. C., Baeza Hernández, Y. E., & Dzul Caballero, J. E. (2025). PLA2-R positive primary membranous nephropathy: a case report. International Journal of Research in Medical Sciences, 13(2), 853–856. https://doi.org/10.18203/2320-6012.ijrms20250267

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Section

Case Reports