Is it easy to miss Bombay blood group? A case report
DOI:
https://doi.org/10.18203/2320-6012.ijrms20251004Keywords:
Bombay blood group, O blood group, Incompatible, Reverse group, Anti HAbstract
Bombay blood group is clinically significant blood group as it not compatible with other blood groups, such as A, B, AB, and especially the O type. Transfusion with any other blood group can lead to fatal hemolytic transfusion reactions. This is a case report where Bombay blood group was misdiagnosed as O blood group despite performing forward and reverse blood group on a gel card (column agglutination Technique). While performing, reverse grouping reaction with O cells was not checked as it was not present in the gel card. A simple test like blood grouping should be done with serious intention with incorporation of both forward and reverse grouping (with A, B and O cells), so that no patient receives wrong blood leading to fatal hemolysis due to transfusion.
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References
Thitinat D, Nadia S, Virakan P, Saranporn R, Thunyaluk P, Nateelak K, et al. Distribution of ABO, Rh, and MNS blood groups from students in Walailak University, Thailand: A descriptive cross-sectional study. Clin Epidemiology Glob Health. 2024;2:568.
Yamamoto F, Cid E, Yamamoto M, Blancher A. ABO research in the modern era of genomics. Transfus Med Rev. 2012;26(2):103-18. DOI: https://doi.org/10.1016/j.tmrv.2011.08.002
Dean L, Dean L. Blood groups and red cell antigens. Bethesda: NCBI. 2005.
Mitra R, Mishra N, Rath GP. Blood groups systems. Indian J Anaesth. 2014;58:524–8. DOI: https://doi.org/10.4103/0019-5049.144645
Ekanem E, Poozhikalayil S, Sinha A. The Bombay blood group: how rare is it? A case report and a review of the literature. J Adv Med Med Res. 2020;32:24-9. DOI: https://doi.org/10.9734/jammr/2020/v32i730445
Panch SR, Montemayor-Garcia C, Klein HG: Hemolytic transfusion reactions. N Engl J Med. 2019;381:150-62. DOI: https://doi.org/10.1056/NEJMra1802338
Qadir H, Larik MO, Iftekhar MA. Bombay blood group phenotype misdiagnosed as O phenotype: a case report. Cureus. 2023;15(9):45555. DOI: https://doi.org/10.7759/cureus.45555
Shrivastava M, Navaid S, Peethambarakshan A, Agrawal K, Khan A. Detection of rare blood group, Bombay (Oh) phenotype patients and management by acute normovolemic hemodilution. Asian J Transfus Sci. 2015;9:74–7. DOI: https://doi.org/10.4103/0973-6247.150957
Mallick S, Kotasthane DS, Chowdhury PS, Sarkar S. Bombay blood group: is prevalence decreasing with urbanization and the decreasing rate of consanguineous marriage.Asian J Transfus Sci. 2015;9:129–32. DOI: https://doi.org/10.4103/0973-6247.162695
Suraci N, Mora M. Bombay blood phenotype: Laboratory detection and transfusions recommendations. Int J Blood Transfus Immunohematol. 2016;6:8–11. DOI: https://doi.org/10.5348/ijbti-2016-23-CR-3