Unveiling the journey: a deep dive into healthcare workers’ preparation, concerns, and experiences with the COVID-19 vaccine- a qualitative study
DOI:
https://doi.org/10.18203/2320-6012.ijrms20250973Keywords:
COVID, COVID vaccine, Vaccine adverse effect, Vaccine side effectAbstract
Background: The COVID pandemic had a profound impact on human life globally and presents an unprecedented challenge to public health, food systems, and the world of work. The COVID vaccine is considered as safe and effective for minimising the impact of COVID-19. However, vaccine related adverse event is one of the major reason for vaccine scepticism. Therefore, this study intended to explore post COVID vaccine related adverse effects and concerns among HCWs.
Methods: A qualitative exploratory study was conducted among HCWs of a tertiary care centre, eastern India, who developed vaccine related adverse effects within 7 days of receipt of COVID vaccine. Information was collected by using indepth interview guide from 12 health care professionals. Then, the data was transcribed, systematically coded and analyzed following the thematic framework approach using MAXQDA-2020 software.
Results: After the analysis four main themes were emerged: vaccination perception and readiness; post vaccination aftermath; management of adverse effects; suggestions. Respondents across the demographic group depicted varied concerns and experiences like they received vaccine to motivate other, be part of research and the vaccination. The most common reported adverse events wererange from headache, body ache, fever, altered taste, dizziness to hyperglycemia, irregular heart rate, diarrhoea and dyspnea. Moreover, their experience from first dose of vaccine convinced them to prepare for the 2nd dose with taking adequate fruit, water and rest.
Conclusions: Knowledge about people’s lived experiences and their concerns after receiving COVID-19 vaccine can be used to formulate strategies and awareness programmes to enhance the vaccine uptake in future.
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References
Xiong J, Lipsitz O, Nasri F, Lui LMW, Gill H, Phan L, et al. Impact of COVID-19 pandemic on mental health in the general population: a systematic review. J Affect Disord. 2020;277:55–64. DOI: https://doi.org/10.1016/j.jad.2020.08.001
Siddiqui S, Alhamdi HWS, Alghamdi HA. Recent chronology of COVID-19 pandemic. Front Public Health. 2022;10:778037. DOI: https://doi.org/10.3389/fpubh.2022.778037
Kumari M, Lu RM, Li MC, Huang JL, Hsu FF, Ko SH, et al. A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies. J Biomed Sci. 2022;29:68. DOI: https://doi.org/10.1186/s12929-022-00852-9
Vizheh M, Qorbani M, Arzaghi SM, Muhidin S, Javanmard Z, Esmaeili M. The mental health of healthcare workers in the COVID-19 pandemic: A systematic review. J Diabetes Metab Disord. 2020;19(2):1967-78. DOI: https://doi.org/10.1007/s40200-020-00643-9
Vindrola-Padros C, Andrews L, Dowrick A, Djellouli N, Fillmore H, Bautista Gonzalez E, et al. Perceptions and experiences of healthcare workers during the COVID-19 pandemic in the UK. BMJ Open. 2020;10(11):e040503. DOI: https://doi.org/10.1136/bmjopen-2020-040503
Dhalaria P, Arora H, Singh AK, Mathur M, S AK. COVID-19 Vaccine hesitancy and vaccination coverage in India: an exploratory analysis. Vaccines. 2022;10(5):739. DOI: https://doi.org/10.3390/vaccines10050739
Pormohammad A, Zarei M, Ghorbani S, Mohammadi M, Razizadeh MH, Turner DL, et al. Efficacy and safety of COVID-19 vaccines: a systematic review and meta-analysis of randomized clinical trials. Vaccines. 2021;9(5):467. DOI: https://doi.org/10.3390/vaccines9050467
Priyadarshini NS, Panigrahi S, Jacob J, Krishnan N, Parida SP, Nayak G. Decoding COVID-19 vaccine hesitation: a qualitative study. Int J Community Med Public Health. 2025;12(1):433-41. DOI: https://doi.org/10.18203/2394-6040.ijcmph20244054
Githinji P, MacMillan Uribe AL, Szeszulski J, Rethorst CD, Luong V, Xin L, et al. Public health communication during the COVID-19 health crisis: sustainable pathways to improve health information access and reach among underserved communities. Humanit Soc Sci Commun. 2024;11(1):1218. DOI: https://doi.org/10.1057/s41599-024-03718-7
Panigrahi S, Mohapatra S, Shetty AP, Baby RS, Singh AK. The burden and contributing factors of psychological distress across India during the COVID pandemic. Arch Psychiatr Nurs. 2021;35(6):678-84. DOI: https://doi.org/10.1016/j.apnu.2021.10.003
Salalli R, Dange JR, Dhiman S, Sharma T. Vaccines development in India: advances, regulation, and challenges. Clin Exp Vaccine Res. 2023;12(3):193-208. DOI: https://doi.org/10.7774/cevr.2023.12.3.193
Purohit N, Chugh Y, Bahuguna P, Prinja S. COVID-19 management: the vaccination drive in India. Health Policy Technol. 2022;11(2):100636. DOI: https://doi.org/10.1016/j.hlpt.2022.100636
Bono SA, Faria de Moura Villela E, Siau CS, Chen WS, Pengpid S, Hasan MT, et al. Factors affecting COVID-19 vaccine acceptance: an international survey among low- and middle-income countries. Vaccines. 2021;9(5):515. DOI: https://doi.org/10.3390/vaccines9050515
Sallam M. COVID-19 vaccine hesitancy worldwide: a concise systematic review of vaccine acceptance rates. Vaccines. 2021;9(2):160. DOI: https://doi.org/10.3390/vaccines9020160
Mahato P, Adhikari B, Marahatta SB, Bhusal S, Kunwar K, Yadav RK, et al. Perceptions around COVID-19 and vaccine hesitancy: A qualitative study in Kaski district, Western Nepal. PLOS Glob Public Health. 2023;3(2):e0000564. DOI: https://doi.org/10.1371/journal.pgph.0000564
Sodeify R, Tabrizi FM, Rezaei S. Perceptions of medical staff on COVID-19 vaccination: a qualitative content analysis. J Nurs Midwife Sci. 2024;11(2). DOI: https://doi.org/10.5812/jnms-144182
Yaqub O, Castle-Clarke S, Sevdalis N, Chataway J. Attitudes to vaccination: a critical review. Soc Sci Med. 2014;112:1-11. DOI: https://doi.org/10.1016/j.socscimed.2014.04.018
Khaleel SM, Shanshal SA, Aladul MI. Adverse reactions of different COVID-19 vaccines among healthcare professionals: A qualitative study in Mosul, Iraq. Clin Epidemiol Glob Health. 2022;18:101175. DOI: https://doi.org/10.1016/j.cegh.2022.101175
Alnemari R, Aljohani O, Alnemari A, Awaji M, Alali A, Almarshoud M, et al. Readiness to receive COVID-19 vaccine of general population, healthcare workers and medical students in Jeddah Saudi Arabia. J Healthc Sci. 2021;02(01):20-30. DOI: https://doi.org/10.52533/JOHS.2021.2104
Ng KM, Chu TK, Lau P. Experience of COVID-19 vaccination among primary healthcare workers in Hong Kong: a qualitative study. Vaccines. 2022;10(9):1531. DOI: https://doi.org/10.3390/vaccines10091531
Sv P, Tandon J, Vikas, Hinduja H. Indian citizen’s perspective about side effects of COVID-19 vaccine- a machine learning study. Diabetes Metab Syndr Clin Res Rev. 2021;15(4):102172. DOI: https://doi.org/10.1016/j.dsx.2021.06.009
Menni C, Klaser K, May A, Polidori L, Capdevila J, Louca P, et al. Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study. Lancet Infect Dis. 2021;21(7):939-49. DOI: https://doi.org/10.1016/S1473-3099(21)00224-3
Mohsin M, Mahmud S, Uddin Mian A, Hasan P, Muyeed A, Ali TM, et al. Side effects of COVID-19 vaccines and perceptions about COVID-19 and its vaccines in Bangladesh: a cross-sectional study. Vaccine X. 2022;12:100207. DOI: https://doi.org/10.1016/j.jvacx.2022.100207
Mittal A, Jain B, Varshney AM, Garg G, Sachan D, Singh RB. Adverse effects after first and second dose of covishield and covaxin: a longitudinal study. J Fam Med Prim Care. 2022;11(11):7339-45. DOI: https://doi.org/10.4103/jfmpc.jfmpc_885_22
Majumder MAA, Bharatha A, Kumar S, Chatterjee M, Gupta S, Harewood H, et al. Self-reported side effects of COVID-19 vaccines among health professions students in India. Peer J. 2024;12:e17083. DOI: https://doi.org/10.7717/peerj.17083
El Hilali S, Benmlih S, Haroun AE, Zeghari Z, Khalis M, Frindy M, et al. Adverse effects of COVID-19 vaccines in the Moroccan adults and children during the pandemic. Clin Epidemiol Glob Health. 2024;28:101689. DOI: https://doi.org/10.1016/j.cegh.2024.101689
Beatty AL, Peyser ND, Butcher XE, Cocohoba JM, Lin F, Olgin JE, et al. Analysis of COVID-19 vaccine type and adverse effects following vaccination. JAMA Netw Open. 2021;4(12):e2140364. DOI: https://doi.org/10.1001/jamanetworkopen.2021.40364
Riad A, Pokorná A, Attia S, Klugarová J, Koščík M, Klugar M. Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic. J Clin Med. 2021;10(7):1428. DOI: https://doi.org/10.3390/jcm10071428
Al-Bawab R, Abu-Farha R, El-Dahiyat F, Nassar RI, Zawiah M. A qualitative assessment of the adverse effects associated with COVID-19 vaccines: a study from Jordan. J Pharm Policy Pract. 2023;16(1):100. DOI: https://doi.org/10.1186/s40545-023-00605-5
Kang B, Chu H, Youn BY, Leem J. Prevention and management of adverse events following COVID-19 vaccination using traditional Korean medicine: An online survey of public health doctors. World J Clin Cases. 2022;10(28):10053-65. DOI: https://doi.org/10.12998/wjcc.v10.i28.10053