Unusual coexistence between lupus nephritis and neurofibromatosis 1: a case report and review of previous cases

Manoj Kumar Roy, Rajdeep Basu, Jotideb Mukhopadhyay, Rajat Choudhuri


The association of Neurofibromatosis 1 (NF 1), an autosomal dominant genetic disease with autoimmune diseases like systemic lupus erythematosus is rare, five case reports are there in medical literature showing such association. Here we have documented a case of Lupus nephritis associated with Neurofibromatosis 1 diagnosed in the same setting, in a 24 years old female patient presented with oliguria, hypertension, anasarca, cafe-au-lait spots, palmer freckling, subcutaneous nodules, alopecia areata and positive family history for NF 1.


Systemic lupus erythematosus, Lupus nephritis, Neurofibromatosis 1, Neurofibromin

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