Heart’s secret encounter-extra skeletal Ewings sarcoma with cardiac involvement in adult: a case report

Authors

  • Arppana Thomas Department of Medicine, Travancore Medical College, Kollam, Kerala, India
  • Sameer Salahuddin Department of Oncology, Travancore Medical College, Kollam, Kerala, India
  • Deepu Rajendran Department of Cardiology, Travancore Medical College, Kollam, Kerala, India
  • R. Legha Department of General Medicine, Travancore Medical College, Kollam, Kerala, India
  • Praseeda Department of Pathology, Travancore Medical College, Kollam, Kerala, India
  • Chandni Thomas Department of Pathology, Travancore Medical College, Kollam, Kerala, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20250367

Keywords:

Ewing’s sarcoma, Infiltrative cardiac mass, Cardiac metastasis

Abstract

Ewing sarcoma is a rare, aggressive malignant tumour predominantly arising from bone or soft tissue in adolescents and young adults. Primary cardiac involvement is exceedingly uncommon, usually occurring as a result of metastatic spread. Here, we present a case of 22-year-old male with an atypical primary cardiac presentation of Ewings sarcoma, posing significant diagnostic challenges. A detailed evaluation revealed disseminated malignancy, including cardiac and systemic involvement. This report underscores the importance of rare malignancies in atypical cardiac presentations and highlights the value of a multidisciplinary approach in diagnosis and treatment.  

 

Metrics

Metrics Loading ...

References

Sobh E, El-Sheshtawy WH, Anis SE. Primary pulmonary extra skeletal Ewing sarcoma/ primitive neuroectodermal tumor: two case reports. Egypt J Bronchol. 2017;11:161-4. DOI: https://doi.org/10.4103/ejb.ejb_48_16

Di Franco A, Gaudino M, Weinsaft JW, Shawn CP, Navneet N, Saadat AK, et al. “Second” primary cardiac sarcoma in a patient with Ewing sarcoma. Always expect the unexpected. Ann Thorac Surg. 2017;103(2):e131-3. DOI: https://doi.org/10.1016/j.athoracsur.2016.07.063

Khanna N, Pandey A, Bajpai J. Metastatic Ewing’s sarcoma: revisiting the “evidence on the fence”. Indian J Med Paediatr Oncol. 2017;38(02):173-81.

Petrovic M, Zhao B, Thangam M, Pranav L, Maximilian BL, Biswajit K, et al. Ewing sarcoma in the right ventricle. Tex Heart Inst J. 2016;43(5):458-60. DOI: https://doi.org/10.14503/THIJ-15-5330

Marina NM, Liu Q, Donaldson SS, Charles AS, Gregory TA, Kevin CO, et al. Longitudinal follow-up of adult survivors of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Cancer. 2017;123(13):2551-60. DOI: https://doi.org/10.1002/cncr.30627

Biswas B, Bakhshi S. Management of Ewing sarcoma family of tumors: current scenario and unmet need. World J Orthop. 2016;7(09):527-38. DOI: https://doi.org/10.5312/wjo.v7.i9.527

Murad R, Bakkar R, Sukkar R, Mahmoud F, Al-Dairy A. A Case of Ewing Sarcoma Presenting with Cardiac Metastasis. World J Pediatr Congenit Heart Surg. 2019;10(5):632-4. DOI: https://doi.org/10.1177/2150135119846047

Ratna Jerusha JF, Raghunath V, Reginald BA, Reddy BS, Kamal F, Reddy S. Ewing’s sarcoma: A rare case report. SRM J Res Dent Sci. 2021;12:172-6. DOI: https://doi.org/10.4103/srmjrds.srmjrds_37_21

Ushigusa J, Mukae Y, Takamatsu M, Nogami E, Furutachi A, Itoh M, et al. Adult-onset primary Ewing's sarcoma of the right atrium: a case report. Surg Case Rep. 2019;5(1):171. DOI: https://doi.org/10.1186/s40792-019-0727-1

Cui M, Zhai D, Liu Y, Zhou X, Wang T, Wang L, et al. Case report: Primary mediastinal Ewing's sarcoma presenting with chest tightness. Front Oncol. 2023;12:1020339. DOI: https://doi.org/10.3389/fonc.2022.1020339

Fahad N, Hamideh D, Zareef R, Akel S. A Massive Ewing Sarcoma of the Rib: A Case Report with Literature Review. Case Rep Pediatr. 2022;2022:6921004. DOI: https://doi.org/10.1155/2022/6921004

Shet N, Stanescu L, Deutsch G. Primary extraosseous Ewing sarcoma of the lung: case report and literature review. Radiol Case Rep. 2013;8:832. DOI: https://doi.org/10.2484/rcr.v8i2.832

Downloads

Published

2025-02-17

How to Cite

Thomas, A., Salahuddin, S., Rajendran, D., Legha, R., Praseeda, & Thomas, C. (2025). Heart’s secret encounter-extra skeletal Ewings sarcoma with cardiac involvement in adult: a case report. International Journal of Research in Medical Sciences, 13(3), 1280–1284. https://doi.org/10.18203/2320-6012.ijrms20250367

Issue

Section

Case Reports