DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20150135

Thyroid disorders and fertility

Nilay Karaca, Yaşam Kemal Akpak

Abstract


Reproductive function is a vital process for continuation of life and requires an appropriate endocrine, molecular and cellular organization. In every stage starting from maturation of ovarian follicle up to implantation of the embryo, a convenient endocrine environment including normal thyroid hormone levels is of utmost importance. After the initial revelation of the correlation between reproductive health and thyroid functions in numerous studies have emphasized that both hyperthyroidism (OHT) and hypothyroidism (OH) are effective in female reproductive system, though varyingly. Our aim in this review is to evaluateeffects of hyper- and hypothyroidism on fertility and also discuss relationship of infertility and assisted reproductive techniques (ART) regarding their effects over thyroid functions and auto-immunity under the guidance of current information.


Keywords


Adverse pregnancy outcome, Hyperthyroidism, Hypothyroidism, Levothyroxine, Thyroid autoimmunity

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References


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