Association between rheumatoid arthritis and atrial fibrillation: a new perspectives

Marcos Velasco Rea; Steveen Ayala Velasco; Milipsa Pozo Andrade; Carlos Cruz Lozada; Jeremy Calderón Torres; Irene Cervantes Chávez; José Castillo Gálvez; Steven Suárez Velastegui

doi:10.18203/2320-6012.ijrms20251013

Authors

Marcos Velasco Rea Ministry of Public Health, Quito, Ecuador
Steveen Ayala Velasco Ministry of Public Health, Quito, Ecuador
Milipsa Pozo Andrade Armed Forces Hospital, Quito, Ecuador
Carlos Cruz Lozada Armed Forces Hospital, Quito, Ecuador
Jeremy Calderón Torres Armed Forces Hospital, Quito, Ecuador
Irene Cervantes Chávez UDLA, University, Quito, Ecuador
José Castillo Gálvez UDLA, University, Quito, Ecuador
Steven Suárez Velastegui UDLA, University, Quito, Ecuador

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251013

Keywords:

Atrial fibrillation, Rheumatoid arthritis, Epidemiology, Pathophysiology, Management

Abstract

Rheumatoid arthritis (RA) is a disease with an autoimmune component that directly and indirectly affects various organs, causing significant damage and complications. However, knowledge about the subject and its association with atrial fibrillation (AF) is limited, making its study important due to its close relationship with the incidence of acute coronary syndrome (ACS). AF is the most common cardiac arrhythmia worldwide, showing a significant increase in morbidity and mortality in people who suffer from it. RA characterized by being a systemic inflammatory disease, affects 0.5-1.0% of the adult population. It is associated with a higher incidence of cardiac arrhythmias such as AF. Several epidemiological studies find that the risk of AF is increased in RA compared to the general population. Considering that inflammation plays an important role in AF, RA may be involved in the onset and development of AF. This review summarizes the epidemiology, pathophysiology, and management of AF in patients with RA.

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