Rekindling the flame: erythema Induratum of bazin as a manifestation of latent tuberculosis

Authors

  • Kambhampati Sailaja Mediciti Institute of Medical Sciences, Ghanpur, Medchal, India
  • Yeluri Manasa Medi Citi Institute of Medical Sciences, Ghanpur, Medchal, India
  • E. P. Raj Kirit Celestee Skin Laser and Hair Clinic, Hyderabad, India
  • Attili Sasi Kiran Visakha Institute of Skin and Allergy, Visakhapatnam, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251331

Keywords:

Erythema induratum of bazin, Tuberculid, Tuberculosis infection, Chronic recurrent plaques, Doxycycline, Hydroxychloroquine, Anti-tubercular therapy

Abstract

Erythema Induratum of Bazin is considered a type of tuberculid—a hypersensitivity reaction to Mycobacterium tuberculosis antigens in individuals with underlying tuberculosis infection. EIB primarily occurs in middle-aged women but can also be seen in men, particularly those with predisposing conditions such as diabetes or vascular insufficiency. We report a case of erythema Induratum of Bazin in an elderly diabetic male who present with chronic recurrent, tender erythematous plaques with oozing, crusting and ulceration over both lower limbs with a past history of pleural tuberculosis. Initially he was treated with doxycycline and hydroxychloroquine, but his lesions worsened. However, after starting ATT his condition improved. Early diagnosis and treatment are crucial in preventing associated morbidity and complications.

 

Metrics

Metrics Loading ...

References

Yang K, Li T, Zhu X, Zou Y, Liu D. Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report. BMC Infect Dis. 2021;21(1):747. DOI: https://doi.org/10.1186/s12879-021-06454-4

Dannenberg AM. Delayed-type hypersensitivity and cell-mediated immunity in the pathogenesis of tuberculosis. Immunol Today. 1991;12(7):228-33. DOI: https://doi.org/10.1016/0167-5699(91)90035-R

Delogu G, Sali M, Fadda G. The biology of mycobacterium tuberculosis infection. Mediterr J Hematol Infect Dis. 2013;5(1):2013070. DOI: https://doi.org/10.4084/mjhid.2013.070

Dhattarwal N, Ramesh V. Tuberculids: A Narrative Review. Indian Dermatol Online J. 2023;14(3):320-9. DOI: https://doi.org/10.4103/idoj.idoj_284_22

Alothman A, Al Qahtani M, Al-Khenaizan S. Erythema induratum: what is the role of Mycobacterium tuberculosis. Ann Saudi Med. 2007;27(4):298-300. DOI: https://doi.org/10.5144/0256-4947.2007.298

Diaz Cascajo C, Borghi S, Weyers W. Panniculitis: definition of terms and diagnostic strategy. Am J Dermatopathol. 2000;22(6):530-49. DOI: https://doi.org/10.1097/00000372-200012000-00009

Santos JB dos, Figueiredo AR, Ferraz CE, Oliveira MH de, Silva PG da, Medeiros VLS de. Cutaneous tuberculosis: diagnosis, histopathology and treatment. A Bras Dermatol. 2014;89(4):545-55. DOI: https://doi.org/10.1590/abd1806-4841.20142747

Micheletti RG. Treatment of cutaneous vasculitis. Front Med (Lausanne). 2022;9:1059612. DOI: https://doi.org/10.3389/fmed.2022.1059612

Mascaró JM, Baselga E. Erythema induratum of bazin. Dermatol Clin. 2008;26(4):439-45. DOI: https://doi.org/10.1016/j.det.2008.05.007

Na SY, Park SY, Cho HH. Application of IFN‐γ releasing assay for the diagnosis of erythema induratum of Bazin. J European Acad of Dermatol and Venereol. 2014;28(1):41-5. DOI: https://doi.org/10.1111/jdv.12052

Bauzá A, España A, Idoate M. Cutaneous polyarteritis nodosa. Br J Dermatol. 2002;146(4):694-9. DOI: https://doi.org/10.1046/j.1365-2133.2002.04624.x

Gilchrist H, Patterson JW. Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management. Dermatol Ther. 2010;23(4):320-7. DOI: https://doi.org/10.1111/j.1529-8019.2010.01332.x

Horio T, Imamura S, Danno K, Ofuji S. Potassium iodide in the treatment of erythema nodosum and nodular vasculitis. Arch Dermatol. 1981;117(1):29-31. DOI: https://doi.org/10.1001/archderm.1981.01650010035020

Downloads

Published

2025-04-29

How to Cite

Sailaja, K., Manasa, Y., Raj Kirit, E. P., & Kiran, A. S. (2025). Rekindling the flame: erythema Induratum of bazin as a manifestation of latent tuberculosis. International Journal of Research in Medical Sciences, 13(5), 2176–2179. https://doi.org/10.18203/2320-6012.ijrms20251331

Issue

Section

Case Reports