The influence of age and BMI on foot progression angle in knee osteoarthritis: a correlation analysis

Aavrati Rastogi; Roop B. Kalia; Pradeep K. Meena

doi:10.18203/2320-6012.ijrms20251300

Authors

Aavrati Rastogi Department of Orthopedics, AIIMS Rishikesh, Uttarakhand, India
Roop B. Kalia Department of Orthopedics, AIIMS Rishikesh, Uttarakhand, India https://orcid.org/0000-0002-3418-5942
Pradeep K. Meena Department of Orthopedics, AIIMS Rishikesh, Uttarakhand, India https://orcid.org/0000-0001-7278-3671

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251300

Keywords:

Foot progression angle, Knee adduction moment, Osteoarthritis

Abstract

Background: Knee osteoarthritis (KOA) is a degenerative joint disease, often associated with age and body mass index (BMI), critical demographic factors influencing its progression. The Foot Progression Angle (FPA), a measure of foot alignment, has been studied as a potential contributor to the development and progression of KOA.

Methods: A comprehensive prospective analysis investigated the relationship between age, BMI, and FPA in individuals diagnosed with KOA. The study included data from participants categorized based on their Kellgren-Lawrence (K/L) grades: K/L grade II and K/L grade III. Correlation coefficients (R) and p values were meticulously calculated to assess these relationships' strength and statistical significance.

Results: Our correlation analysis in KOA (K/LII and III) showed weak, non-significant correlations between age, BMI, and FPA. Specifically, age was linked with FPA at -0.1415 (p value 0.3499) in K/L 2 and -0.1257 (p value 0.33) in K/L grade 3, while BMI correlations were -0.125 (p value 0.40) in K/L 2 and -0.1402 (p value 0.27) in K/L 3.

Conclusions: While BMI and age are significant factors in KOA, their relationship with FPA is weak and insignificant. This finding paves the way for further research to explore other biomechanical factors that may play a more substantial role in knee OA progression.

Metrics

Metrics Loading ...

References

Shumnalieva R, Kotov G, Monov S. Obesity-related knee osteoarthritis-current concepts. Life. 2023;13(8):1650. DOI: https://doi.org/10.3390/life13081650

Wang S, Mo S, Chung RC, Shull PB, Ribeiro DC, Cheung RT. How foot progression angle affects knee adduction moment and angular impulse in patients with and without medial knee osteoarthritis: a meta‐analysis. Arthritis Care Res (Hoboken). 2021;73(12):1763-76. DOI: https://doi.org/10.1002/acr.24420

Seagers K, Uhlrich SD, Kolesar JA, Berkson M, Kaneda JM, Beaupre GS, et al. Changes in foot progression angle during gait reduce the knee adduction moment and do not increase hip moments in individuals with knee osteoarthritis. J Biomech. 2022;141:111204.

Felson DT, Goggins J, Niu J, Zhang Y, Hunter DJ. The effect of body weight on knee osteoarthritis progression depends on alignment. Arthritis Rheum. 2004;50(12):3904-9. DOI: https://doi.org/10.1002/art.20726

Rogers MW, Wilder FV. The association of BMI and knee pain among persons with radiographic knee osteoarthritis: a cross-sectional study. BMC Musculoskelet Disord. 2008;9:1-6. DOI: https://doi.org/10.1186/1471-2474-9-163

Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA. 2001;286(2):188-95. DOI: https://doi.org/10.1001/jama.286.2.188

Hutchison L, Grayson J, Hiller C, D'Souza N, Kobayashi S, Simic M. Relationship between knee biomechanics and pain in people with knee osteoarthritis: a systematic review and meta‐analysis. Arthritis Care Res (Hoboken). 2023;75(6):1351-61. DOI: https://doi.org/10.1002/acr.25001

Miyazaki T, Wada M, Kawahara H, Sato M, Baba H, Shimada S. Dynamic load at baseline can predict radiographic disease progression in medial compartment knee osteoarthritis. Ann Rheum Dis. 2002;61(7):617-22. DOI: https://doi.org/10.1136/ard.61.7.617

Rutherford DJ, Hubley-Kozey CL, Deluzio KJ, Stanish WD, Dunbar M. Foot progression angle and the knee adduction moment: a cross-sectional investigation in knee osteoarthritis. Osteoarthritis Cartilage. 2008;16(8):883-9. DOI: https://doi.org/10.1016/j.joca.2007.11.012

Xia H, Charlton JM, Shull PB, Hunt MA. Portable, automated foot progression angle gait modification via a proof-of-concept haptic feedback-sensorized shoe. J Biomech. 2020;107:109789. DOI: https://doi.org/10.1016/j.jbiomech.2020.109789

Seagers K, Uhlrich SD, Kolesar JA, Berkson M, Kaneda JM, Beaupre GS, et al. Changes in foot progression angle during gait reduce the knee adduction moment and do not increase hip moments in individuals with knee osteoarthritis. J Biomech. 2022;141:111204. DOI: https://doi.org/10.1016/j.jbiomech.2022.111204

Bowsher KA, Vaughan CL. Effect of foot-progression angle on hip joint moments during gait. J Biomech. 1995;28(6):759-62. DOI: https://doi.org/10.1016/0021-9290(94)00123-L

Baliunas AJ, Hurwitz DE, Ryals AB, Karrar A, Case JP, Block JA, et al. Increased knee joint loads during walking are present in subjects with knee osteoarthritis. Osteoarthritis Cartilage. 2002;10(7):573-9. DOI: https://doi.org/10.1053/joca.2002.0797

Thomas RH, Resnick D, Alazraki NP, Daniel D, Greenfield R. Compartmental evaluation of osteoarthritis of the knee: a comparative study of available diagnostic modalities. Radiol. 1975;116(3):585-94. DOI: https://doi.org/10.1148/116.3.585