Neonatal neuroblastoma in a tertiary health facility in Southwest Nigeria: a case report

Ifedayo O. Fasoranti; Abiodun J. Kareem; Temitayo O. Bewaji; Ibitoye B. Samuel; Korede O. Oluwatuyi; Abiola Okunade; Idowu R. Akinsuwa; Adesola O. Kareem; Babatunde D. Babalola; Timilehin L. Taiwo; Adebola B. Ganiyu; Akinbowale R. Eniowo

doi:10.18203/2320-6012.ijrms20251320

Authors

Ifedayo O. Fasoranti Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Abiodun J. Kareem Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Temitayo O. Bewaji Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Ibitoye B. Samuel Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Korede O. Oluwatuyi Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Abiola Okunade Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Idowu R. Akinsuwa Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Adesola O. Kareem Department of Community Health, Federal Medical Centre, Owo, Ondo state, Nigeria
Babatunde D. Babalola Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Timilehin L. Taiwo Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Adebola B. Ganiyu Department of Paediatrics, Federal Medical Centre, Owo, Ondo state, Nigeria
Akinbowale R. Eniowo Department of Obstetrics and Gynaecology, Federal Medical Centre, Owo, Ondo state, Nigeria

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251320

Keywords:

Abdominal mass, Neonatal neuroblastoma, Nigeria

Abstract

Neuroblastoma is a pediatric neoplasm diagnosed in infancy and occurs mainly in the abdomen. There is a paucity of data in developing countries, including Nigeria. Therefore, this study aimed to report the first case of neonatal neuroblastoma in a Federal Medical Centre, Owo, Ondo state, Nigeria. We described a 4-hour-old term female neonate with multiple subcutaneous nodules and a right-sided intra-abdominal mass that crosses the midline. Examination reviewed an ill-looking neonate with multiple, painless anterior abdominal wall subcutaneous nodules and abdominal distension with a palpable right-sided abdominal mass. The abdominal MRI revealed a right abdominal mass separated from the normal-shaped kidney and an enlarged liver with multiple nodules. The liver enzymes and urinary vanillylmandelic acid were elevated. Neonatal neuroblastoma, though rarely reported among Nigerian neonates, should be considered in the differential diagnosis of abdominal mass, and the awareness should be increased among sonographers for early detection.

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