Extranodal NK/T-cell lymphoma, nasal type: a case report
DOI:
https://doi.org/10.18203/2320-6012.ijrms20250998Keywords:
NK/T cell lymphoma, EN-NK/T-NT, ENKTL, Nasal obstruction, Epstein Barr virusAbstract
Extranodal NK/T-cell lymphoma, nasal type (ENKTL-NT), is a rare and aggressive malignancy associated with Epstein-Barr virus (EBV). Its clinical presentation includes midfacial destruction, ulceration, and nasal obstruction, often leading to misdiagnosis. A 43-year-old male presented with a rapidly progressive nasal lesion. Clinical evaluation, imaging, and histopathological analysis with immunohistochemistry confirmed ENKTL-NT. Treatment includes radiotherapy and chemotherapy, improving survival rates, though prognosis remains poor in advanced cases. Early diagnosis is crucial for better outcomes.
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Andreou A, Thermos G, Sklavounou-Andrikopoulou A. Extranodal NK/T cell lymphoma, nasal type with palatal involvement: A rare case report and literature review. Head Neck Pathol. 2020;15(2):621-7. DOI: https://doi.org/10.1007/s12105-020-01182-8
Akbar M, Clasen-Linde E, Specht L. Extranodal NK/T-cell lymphoma, nasal type, with extranasal presentation - a case report and a review of the literature. Acta Oncologica (Stockholm, Sweden). 2020;59(12):1480-7. DOI: https://doi.org/10.1080/0284186X.2020.1795250
Allen PB, Lechowicz MJ. Management of NK/T-Cell Lymphoma, Nasal Type. J Oncol Pract. 2019;15(10):513-20. DOI: https://doi.org/10.1200/JOP.18.00719
Lungu M, Telehuz A, Voinescu DC, Sapira V, Trifan A, Elkan EM, et al. NK/T-cell non-Hodgkin lymphoma: Case report and review of the literature. Exp Ther Med. 2021;21(1):91. DOI: https://doi.org/10.3892/etm.2020.9523
Daines BS, Varman RM, Nguyen TQ. Extranodal natural killer/T-cell lymphoma nasal type. Proc (Bayl Univ Med Cent). 2022;35(5):672-4. DOI: https://doi.org/10.1080/08998280.2022.2071074
Costa RO, Pereira J, Lage LAPC, Baiocchi OCG. Extranodal NK-/T-cell lymphoma, nasal type: what advances have been made in the last decade? Front Oncol. 2023;13:1175545. DOI: https://doi.org/10.3389/fonc.2023.1175545
Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y. Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation. Microorganisms. 2021;9(7):1381. DOI: https://doi.org/10.3390/microorganisms9071381
Yan Z, Yao S, Wang Z, Zhou W, Yao Z, Liu Y. Treatment of extranodal NK/Tcell lymphoma: From past to future. Front Immunol. 2023;14:1088685. DOI: https://doi.org/10.3389/fimmu.2023.1088685
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