Uterine rupture in a pregnancy without previous uterine scarring and induction of labor with misoprostol: a case report

Authors

  • Verónica Quintana Islas Department of Gynecology and Obstetrics, Hospital General de Cancún “Dr. Jesús Kumate Rodríguez”, Cancún, México; Facultad de Medicina de la Universidad Autónoma de Yucatán, México
  • Olga Cid Gómez Department of Gynecology and Obstetrics, Hospital General de Cancún “Dr. Jesús Kumate Rodríguez”, Cancún, México; Benito Juárez Autonomous University of Oaxaca, Oaxaca, México
  • Christopher Díaz Aldeco Castillo Díaz Aldeco Castillo Department of Gynecology and Obstetrics, Hospital General de Cancún “Dr. Jesús Kumate Rodríguez”, Cancún, México; Facultad de Medicina de la Universidad Autónoma de Yucatán, México
  • Alexis Emir Noguera Echeverría Facultad de Medicina de la Universidad Autónoma de Yucatán, México; Department of Surgery, Mérida Clinic-Hospital, ISSSTE, Mérida, México
  • María Fernanda Ibarra Guerrero Facultad de Medicina de la Universidad Autónoma de Yucatán, México; Department of Pediatrics, Mérida Clinic-Hospital, ISSSTE, Mérida, México
  • Leonel Andrés Barrera Heredia Department of Gynecology and Obstetrics, Universidad Autónoma de Yucatán, Yucatán, México
  • Guiscentia Rose Tharlene Auguste Universidad Marista, Mérida, Yucatán, México
  • Alison Mariel Ruz Alcocer Universidad Anáhuac Mayab, Mérida, Yucatán, México
  • Natalia Aleli Gómez Marfil Universidad para el Bienestar Benito Juárez García, Yucatán, México
  • Ambar Sahian Dominguez de la Cruz Universidad para el Bienestar Benito Juárez García, Yucatán, México
  • Francisco Alejandro Nava Rodríguez Universidad Anáhuac Mayab, Mérida, Yucatán, México

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251117

Keywords:

Uterine rupture, Rare obstetric emergency, Labor, Uterine bleeding, Misoprostol, Hysterectomy, Fetal death, Risk factors

Abstract

Uterine rupture (UR) is a serious obstetric complications involving the uterine wall injury during pregnancy or delivery. It occurs in one in 5,000 to 7,000 births, with about up to 10% requiring hysterectomy. Risk factors include previous uterine scarring, use of uterotonics, induction of labor, history of uterine trauma, high multiparity, abnormal placentation, fetal abnormalities, advanced maternal age, a high body mass index (BMI), and lack of prenatal monitoring. A 36-year-old Mexican female with five previous pregnancies, all terminated by vaginal route, with poor prenatal monitoring and high blood pressure. Prostaglandin E1 (misoprostol 50 mcg) was used in two doses with the patient starting labor in an active phase, but presented moderate abdominal pain, no fetal heart rate, and weak transvaginal bleeding. A probable detachment of placenta and fetal death was suspected; therefore, it was decided to perform an emergency caesarean section. This case highlights the importance of obstetric care, particularly in relation to gestational hypertension, induction of labor, and severe complications as uterine rupture. In our patient misoprostol was used to prepare the cervix and promote induction of term delivery, but its administration led to uterine rupture. UR is a rare obstetric emergency that requires immediate attention and proper surgical management. It is more common in women with previous uterine scarring and can occur in a uterus without a surgical history. Risk factors and clinical monitoring are crucial for early warning signs. Misoprostol use should be adjusted based on patient characteristics and pre-existing factors. Timely diagnosis and treatment are essential to reduce morbidity and mortality.

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References

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Published

2025-04-24

How to Cite

Quintana Islas, V., Cid Gómez, O., Díaz Aldeco Castillo, C. D. A. C., Noguera Echeverría, A. E., Ibarra Guerrero, M. F., Barrera Heredia, L. A., Tharlene Auguste, G. R., Ruz Alcocer, A. M., Gómez Marfil, N. A., Dominguez de la Cruz, A. S., & Nava Rodríguez, F. A. (2025). Uterine rupture in a pregnancy without previous uterine scarring and induction of labor with misoprostol: a case report. International Journal of Research in Medical Sciences, 13(5), 2107–2112. https://doi.org/10.18203/2320-6012.ijrms20251117

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Section

Case Reports