Management of internet addiction in an 18-year-old female with endoxifen: a case report
DOI:
https://doi.org/10.18203/2320-6012.ijrms20252803Keywords:
Adolescent mental health, Treatment outcomes, Impulsivity, Clonazepam, Internet addiction, Endoxifen, VilazodoneAbstract
Internet addiction has emerged as one of the rising health concerns in the adolescent age group in recent years, which is traditionally treated with psychotherapy. However, some patients require pharmacotherapy to manage their symptoms. This case report explores the treatment of an 18-year-old female diagnosed with internet addiction. The treatment regimen included endoxifen as adjunctive therapy alongside vilazodone, clonazepam and behavioural therapy. Over one-month period, notable improvements were observed in her symptoms, assessed through clinical global impressions and standardized internet addiction testing. The finding indicates that endoxifen, a direct protein kinase C (PKC) inhibitor, may be an effective treatment for such patients, especially those who do not respond to conventional therapies. This case report emphasizes the future studies focusing on the role of endoxifen in patients with behavioural addiction.
Metrics
References
Joseph J, Varghese A, Vr V, Dhandapani M, Grover S, Sharma S, et al. Prevalence of internet addiction among college students in the Indian setting: a systematic review and meta-analysis. Gen Psychiatr. 2021;34(4):e100496. DOI: https://doi.org/10.1136/gpsych-2021-100496
Chadha Y, Patil R, Toshniwal S, Sinha N. Internet Addiction Management: A Comprehensive Review of Clinical Interventions and Modalities. Cureus. 2024;16(3):e55466. DOI: https://doi.org/10.7759/cureus.55466
Ahmad A, Sheikh S, Khan MA, Chaturvedi A, Patel P, Patel R, et al. Endoxifen: A new, protein kinase C inhibitor to treat acute and mixed mania associated with bipolar I disorder. Bipolar Disord. 2021;23(6):595-603. DOI: https://doi.org/10.1111/bdi.13041
Tharoor H. End of Craving with Endoxifen in Substance Use & Bipolar Disorder. J Clin Pharmacol Ther. 2023;4(3):1048.
Dave M, Shanmugasundaram N. Endoxifen for the management of bipolar disorder with comorbid substance use disorder: A report of two cases. Arch Biol Psychiatr. 2023;1:25-8. DOI: https://doi.org/10.25259/ABP_1_2023
Alavi SS, Ferdosi M, Jannatifard F, Eslami M, Alaghemandan H, Setare M. Behavioral Addiction versus Substance Addiction: Correspondence of Psychiatric and Psychological Views. Int J Prev Med. 2012;3(4):290-4.
Guedes E, Sancassiani F, Carta MG, Campos C, Machado S, King AL, et al. Internet Addiction and Excessive Social Networks Use: What About Facebook? Clin Pract Epidemiol Ment Health. 2016;12:43-8. DOI: https://doi.org/10.2174/1745017901612010043
Volkow ND, Blanco C. Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention. World Psychiat. 2023;22(2):203-29. DOI: https://doi.org/10.1002/wps.21073
Ayub S, Jain L, Parnia S, Bachu A, Farhan R, Kumar H, et al. Treatment Modalities for Internet Addiction in Children and Adolescents: A Systematic Review of Randomized Controlled Trials (RCTs). J Clin Med. 2023;12(9):3345. DOI: https://doi.org/10.3390/jcm12093345
Ahmad A, Sheikh S, Shah T, Reddy MS, Prasad B, Verma KK, et al. Endoxifen, a New Treatment Option for Mania: A Double-Blind, Active-Controlled Trial Demonstrates the Antimanic Efficacy of Endoxifen. Clin Transl Sci. 2016;9(5):252-9. DOI: https://doi.org/10.1111/cts.12407
Kannappan Y. Endoxifen for the Management of Pathological Gambling in a Male Patient Who Overinvested in Cryptocurrency: A Case Report. Ind J Priv Psychiatry. 2024;18(2):88-90. DOI: https://doi.org/10.5005/jp-journals-10067-0184
Downloads
Published
How to Cite
Issue
Section
