Profiling of kidney disease patients undergoing hemodialysis
DOI:
https://doi.org/10.18203/2320-6012.ijrms20251434Keywords:
Kidney failure, Hemodialysis, Hypertension, Diabetes, Medication misuse, Regional disparities, Haryana, Uttar Pradesh, ESRD, Risk factorsAbstract
Background: Kidney failure represents a substantial global health challenge; however, hemodialysis functions as a vital treatment for end-stage renal disease (ESRD). This study offers insights into the causes (and) demographic distribution of kidney failure among patients undergoing hemodialysis in Haryana and Uttar Pradesh, India. Although there are various factors contributing to this condition, understanding the nuances is essential because it can help to formulate better healthcare strategies.
Methods: A cross-sectional study (conducted by DCDC kidney care) involved 3,254 patients undergoing hemodialysis across Haryana and Uttar Pradesh. Data collected on demographic parameters, clinical characteristics and as per the clinical history of kidney failure were analyzed. Descriptive statistics helped to analyse age, gender and perceived causes of kidney failure; however, regional variations were highlighted. This study is significant, because it provides insights into the complexities of kidney failure, although it does have its limitations.
Results: The majority of patients undergoing hemodialysis were middle-aged, with the highest representation in the 41-50 years (25.1%) and 31-40 years (22.1%) age groups. Male patients constituted 70.9% of the population. Hypertension was identified as the most prevalent cause of kidney failure (60.35%), followed by diabetes (17.02%) and painkiller misuse (21.30%). Self-reported causes varied regionally; blood pressure was the leading cause in both Haryana (68.3%) and Uttar Pradesh (45.6%). However, excessive drug use (13.7%) and other unspecified causes (15.6%) were more prominent in Uttar Pradesh. These findings underscore regional disparities in awareness, risk factors and healthcare practices.
Conclusions: The study highlights the multifactorial nature of kidney failure, with hypertension, diabetes, and medication misuse being the primary contributors. Regional variations in the perceived causes of kidney failure reflect differences in risk factor awareness and healthcare practices between Haryana and Uttar Pradesh. Tailored interventions addressing modifiable risk factors and regional disparities are crucial for effective prevention and management of kidney failure.
Metrics
References
Chaudhari ST, Sadavarte AV, Chafekar D. Clinical profile of end stage renal disease in patients undergoing hemodialysis. MVP J Med Sci. 2017;4(1):8-13. DOI: https://doi.org/10.18311/mvpjms/0/v0/i0/8555
Zhu Y, Lai Y, Hu Y, Fu Y, Zhang Z, Lin N, et al. The mechanisms underlying acute myocardial infarction in chronic kidney disease patients undergoing hemodialysis. Biomed Pharmacotherapy. 2024;177:117050. DOI: https://doi.org/10.1016/j.biopha.2024.117050
Stengel B, Metzger M, Combe C, Jacquelinet C, Briançon S, Ayav C et al. Risk profile, quality of life and care of patients with moderate and advanced CKD: The French CKD-REIN Cohort Study. Nephrol Dialysis Transplantation. 2019;34(2):277-86. DOI: https://doi.org/10.1093/ndt/gfy058
Dincer N, Dagel T, Afsar B, Covic A, Ortiz A, Kanbay M. The effect of chronic kidney disease on lipid metabolism. Int Urol Nephrol. 2019;51:265-77. DOI: https://doi.org/10.1007/s11255-018-2047-y
Gejjalagere CN, Iyer Murali NV, Yogesh S, Mohammed AI, Hemachandran D, Narendran K, et al. Comprehensive Clinical Profile and Hemodialysis Outcomes in Patients Attending a Tertiary Care Hospital. Cureus. 2024;16(8):e66816.
Risal SK. Clinical profile of end stage renal disease patients undergoing hemodialysis in a tertiary hospital of Lumbini province, Nepal. Int J Health Sci Res. 2023;3(2):17-20. DOI: https://doi.org/10.52403/ijhsr.20230204
Ghimire M, Vaidya S & Upadhyay HP. Clinicodemographic Profile and Outcome of Maintenance Hemodialysis (MHD) Patients in a Tertiary Hospital of Central Nepal, Chitwan. Kathmandu Univ Med J. 2020;69(1):9-14. DOI: https://doi.org/10.3126/kumj.v18i1.33338
Kumar RU, Shashank J, Swamy N. Study of clinical profile of chronic kidney disease in non-diabetic patients. Int J Adv Med. 2021;8:1113-9. DOI: https://doi.org/10.18203/2349-3933.ijam20212809
Kumar M, Saini S, Parashar L, Chetiwal R, Kalra T, Kalra N. Clinical profile of hemodialysis patients attending a tertiary care hospital in Delhi, India. Int J Community Med Public Health. 2021;8:6000-5.
Burrows NR, Vassalotti JA, Saydah SH. Identifying high-risk individuals for chronic kidney disease: results of the CHERISH Community Demonstration Project. Am J Nephrol. 2018;48(6):447-55. DOI: https://doi.org/10.1159/000495082
Ahmed M, Wani IA, Wani MM, Banday KA. Profile of chronic kidney disease (CKD) patients presenting in a tertiary care center in north India. Int Arch Integr Med. 2018;5(8):72-80.
Kumar M, Saini S, Parashar L, Chetiwal R, Kalra T, Kalra N. Clinical profile of hemodialysis patients attending a tertiary care hospital in Delhi, India. Int J Community Med Publ Heal. 2021;8(12):6000-5. DOI: https://doi.org/10.18203/2394-6040.ijcmph20214604
Chakravarti A, Ukey A, Bajaj P, Saragade P. A Study of Hematological Profile in Patients of Chronic Renal Failure Undergoing Hemodialysis at a Tertiary Health Care Institute. MVP J Med Sci. 2017;4(2):107-12
Jyoti S, Imam A. A Study of Hematological Profile in Patients of Chronic Kidney Disease Undergoing Hemodialysis in a Tertiary Care Hospital, South-West Bihar. Int J Pharm Clin Res. 2023;15(3):884-9.