Psychological disorders and personality characteristics of with gastro-esophageal reflux disease

Authors

  • Asma Manzoor Department of Psychiatry, MGM Medical College & Hospital, Navi Mumbai, Maharashtra
  • Shaunak A. Ajinkya Department of Psychiatry, MGM Medical College & Hospital, Navi Mumbai, Maharashtra
  • Pradeep R. Jadhav Department of Pharmacology, MGM Medical College & Hospital, Navi Mumbai, Maharashtra
  • Rakesh P. Ghildiyal Department of Psychiatry, MGM Medical College & Hospital, Navi Mumbai, Maharashtra

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150157

Keywords:

GERD, GORD, Psychological disorders, Personality traits, Co-morbidity

Abstract

Background: Gastro-esophageal reflux disease (GERD) can be traced back to disorders of the gastro-esophageal junction but several psychological factors interact to affect treatment outcomes. There is sparse literature from India regarding psychological co-morbidity and personality characteristics in patients with GERD.

Aim and Objectives: To study the co-morbid psychological disorders and personality profiles in patients suffering from GERD.

Methods: Two hundred patients with GERD-related symptoms were randomly screened for psychological disorders and personality characteristics using 30-item General Health Questionnaire (GHQ) and Sixteen Personality Factor Questionnaire (16PF) respectively. Patients who screened positive for presence of co-morbid psychological disorders were further interviewed using Structured Clinical Interview for DSM-IV Axis 1 Disorders (SCID-1) to find out the type of psychological disorder.

Results:The prevalenceofpsychological co-morbidity in patients with GERD-related symptoms in our sample was foundto be 40%. Major depressive disorder was the most common psychological disorder found co-morbid in these patients. Alcohol dependence was significantly observed in males; while in females, major depressive disorder and generalized anxiety disorder was more commonly seen. Regarding personality characteristics, a higher degree of neuroticism and risk-taking attitudes was found in patients of GERD with associated psychological co-morbidity

Conclusions:This study suggests that the management of GERD may include psychological evaluations and possibly interventions in standard treatment protocols.

 

Metrics

Metrics Loading ...

References

Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadock’s Synopsis of Psychiatry - Behavioral Sciences/ Clinical Psychiatry. 11th ed. New Delhi: Wolters Kluver India) Pvt Ltd; 2015. Chapter 13, Psychosomatic Medicine; p.465-503.

DeVault KR, Castell DO, American College of Gastroenterology. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol. 2005;100(1):190-200.

Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R, Global Consensus Group. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101(8):1900-20.

Söderholm JD. Stress-related changes in oesophageal permeability: filling the gaps of GORD? Gut. 2007;56(9):1177-80.

Fass R. Persistent heartburn in a patient on proton-pump inhibitor. Clin Gastroenterol Hepatol. 2008; 6(4):393-400.

Fass R, Gasiorowska A. Refractory GERD: what is it? Curr Gastroenterol Rep. 2008;10(3):252-7.

Camilleri M, Dubois D, Coulie B, Jones M, Kahrilas PJ, Rentz AM, et al. Prevalence and socioeconomic impact of upper gastrointestinal disorders in the United States: results of the US Upper Gastrointestinal Study. Clin Gastroenterol Hepatol. 2005;3(6):543-52.

Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis. 1976;21(11):953-6.

Goh KL, Wong CH. Gastroesophageal Reflux Disease:An Emerging Disease in Asia. J Gastroenterol Hepatol. 2006;2:118-23.

Ho KY, Kang JY, Seow A. Prevalence of gastrointestinal symptoms in a multiracial Asian population, with particular reference to reflux-type symptoms. Am J Gastroenterol. 1998;93(10):1816-22.

Bhatia SJ, Reddy DN, Ghoshal UC, Jayanthi V, Abraham P, Choudhuri G, et al. Epidemiology and symptom profile of gastroesophageal reflux in the Indian population: report of the Indian Society of Gastroenterology Task Force. Indian J Gastroenterol. 2011;30(3):118-27.

Sharma PK, Ahuja V, Madan K, Gupta S, Raizada A, Sharma MP. Prevalence, severity, and risk factors of symptomatic gastroesophageal reflux disease among employees of a large hospital in northern India. Indian J Gastroenterol. 2011;30(3): 128-34.

Saberi-Firoozi M, Khademolhosseini F, Yousefi M, Mehrabani D, Zare N, Heydari ST. Risk factors of gastroesophageal reflux disease in Shiraz, southern Iran. World J Gastroenterol. 2007;13(41):5486-91.

Mizyed I, Fass SS, Fass R. Gastro-oesophageal reflux disease and psychological comorbidity. Aliment Pharmacol Ther. 2009;29(4):351-8.

Nielzén S, Pettersson KI, Regnéll G, Svensson R. The role of psychiatric factors in symptoms of hiatus hernia or gastric reflux. Acta Psychiatr Scand. 1986;73(2):214-20.

Rey E, García-Alonso M, Moreno-Ortega M, Almansa C, Alvarez-Sanchez A, Díaz-Rubio M. Influence of psychological distress on characteristics of symptoms in patients with GERD: the role of IBS comorbidity. Dig Dis Sci. 2009; 54(2):321-7.

Avidan B, Sonnenberg A, Giblovich H, Sontag SJ. Reflux symptoms are associated with psychiatric disease. Aliment Pharmacol Ther. 2001;15(12): 1907-12.

Whittington J, Huppert FA. Creating invariant subscales of the GHQ-30. Soc Sci Med. 1998; 46(11):1429-40.

Russell MT, Karol D. 16PF fifth edition administrator’s manual. Champaign, IL: Institute for Personality and Ability Testing; 2002.

First MB, Spitzer RL, Gibbon M. Structured Clinical Interview for DSM IV Axis Disorders, New York: State Psychiatric Institute, Biometrics research; 1995.

Rosaida MS, Goh KL. Gastro-oesophageal reflux disease, reflux oesophagitis and non-erosive reflux disease in a multiracial Asian population: a prospective, endoscopy based study. Eur J Gastroenterol Hepatol. 2004;16(5):495-501.

Núñez-Rodríguez MH, Miranda SA. Psychological Factors in Gastroesophageal Reflux Disease Measured by SCL-90-R Questionnaire. Dig Dis Sci. 2008; 53:3071-5.

Wong WM, Lai KC, Lam KF, Hui WM, Hu WH, Lam CL, et al. Prevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study. Aliment Pharmacol Ther. 2003;18(6):

-604.

Jansson C, Nordenstedt H, Wallander MA, Johansson S, Johnsen R, Hveem K, et al. Severe gastro-oesophageal reflux symptoms in relation to anxiety, depression and coping in a population-based study. Aliment Pharmacol Ther. 2007; 26(5): 683-91.

Mohammed I, Nightingale P, Trudgill NJ. Risk factors for gastro-oesophageal reflux disease symptoms: a community study. Aliment Pharmacol Ther. 2005;21(7):821-7.

Chen S, Wang J, Li Y. Is alcohol consumption associated with gastroesophageal reflux disease? J Zhejiang Univ Sci B. 2010;11(6):423–428.

Wang JH, Luo JY, Dong L, Gong J, Tong M. Epidemiology of gastroesophageal reflux disease: a general population-based study in Xi'an of Northwest China. World J Gastroenterol. 2004; 10(11):1647-51.

Johnston BT, Lewis SA, Love AH. Psychological factors in gastro-oesophageal reflux disease. Gut. 1995;36(4):481-2.

Holtmann G, Kriebel R, Singer MV. Mental stress and gastric acid secretion. Do personality traits influence the response? Dig Dis Sci 1990;35(8): 998-1007.

Subic-Wrana C, Beutel ME, Knebel A, Lane RD. Theory of mind and emotional awareness deficits in patients with somatoform disorders. Psychosom Med. 2010;72(4):404-11.

Downloads

Published

2017-01-09

How to Cite

Manzoor, A., Ajinkya, S. A., Jadhav, P. R., & Ghildiyal, R. P. (2017). Psychological disorders and personality characteristics of with gastro-esophageal reflux disease. International Journal of Research in Medical Sciences, 3(6), 1408–1415. https://doi.org/10.18203/2320-6012.ijrms20150157

Issue

Section

Original Research Articles