Probiotics and their benefits in pediatric patients
DOI:
https://doi.org/10.18203/2320-6012.ijrms20252054Keywords:
Microbiota, Probiotics, Respiratory tract diseasesAbstract
Respiratory tract diseases are among the most common infections in childhood and adolescence. In recent years, probiotics have emerged as a promising prophylactic and curative alternative for various digestive, mental and respiratory pathologies. This is attributed to the significant influence that the intestinal microbiota exerts on the immune system. Multiple studies indicate that an impact on the microbiota due to external or internal factors leads to an alteration in the immune system. Among their current uses, they are used for the prevention and treatment of respiratory diseases in children. The studies analyzed show that Lactobacillus casei shows better results in preventing upper respiratory diseases than other probiotics, whether combined or alone. However, the duration of administration is unknown. New advances increasingly point to the positive effect that probiotics show in children, especially those who present repetitive viral or bacterial symptoms. Different investigations open doors and excellent results have been obtained with the use of probiotics.
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Toivonen LV. Burden of recurrent respiratory tract infections in children: a prospective cohort study. Pediatr Infect Dis J. 2016; 35(12):362–9. DOI: https://doi.org/10.1097/INF.0000000000001304
Vouloumanou EK. Probiotics for the prevention of respiratory tract infections: a systematic review. Int J Antimicrob Agents. 2019;343:191–10.
Hao QL. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2011;9:6895. DOI: https://doi.org/10.1002/14651858.CD006895.pub2
Agustina RK. Randomized trial of probiotics and calcium on diarrhea and respiratory tract. nfections in indonesian children. Pediatrics. 2020;129:1155–64. DOI: https://doi.org/10.1542/peds.2011-1379
Mulholland K. Global burden of acute respiratory infections in children: implications for interventions. Ped Pulmonol. 2003;36(6):469-74. DOI: https://doi.org/10.1002/ppul.10344
Kalliomaki MI. Role of intestinal flora in the development of allergy. Op Allergy Clin Immunol. 2013;3:15–20. DOI: https://doi.org/10.1097/00130832-200302000-00003
Chiu LB. Protective microbiota: from localized to long -reaching community. Front Immunol. 2017;8:1678. DOI: https://doi.org/10.3389/fimmu.2017.01678
Budden KF G. Emerging pathogenic links between microbiota and the gutlungaxis. Nat Rev Microbiol. 2017;15(1):55–63. DOI: https://doi.org/10.1038/nrmicro.2016.142
Kumpu MK. Milk containing probiotic Lactobacillus rhamnosus GG and respiratory illness in children: a randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr. 2022;66:1020-3. DOI: https://doi.org/10.1038/ejcn.2012.62
Rautava S SSIE. Specific probiotics in reducing the risk of acute infections in infancy. A randomised,doublé blind, placebo-controlled study. Br J Nutr. 2019;101:1722-6. DOI: https://doi.org/10.1017/S0007114508116282
Hatakka K. Treatment of acute otitis media with probiotics in otitis-prone children-a double-blind, placebo-controlled randomised study. Clin Nutr. 2017;26:314–21. DOI: https://doi.org/10.1016/j.clnu.2007.01.003
Merenstein D. Use of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease the rate of illness in kids: the DRINK study A patient oriented, double-blind, cluster-randomized, placebo-controlled, clinical trial. Eur J Clin Nutr. 2020;64:669–77. DOI: https://doi.org/10.1038/ejcn.2010.65
Hori TK. eduction of Influenza Virus Titerin Aged Mice Fed Lactobacillus case. Clin Diagn Lab Immuno. 2022;1:105. DOI: https://doi.org/10.1128/CDLI.9.1.105-108.2002
KhailovaL B. Lactobacillus rhamnosus GG improves out come in experimental pseudomonas aeruginosa pneumonia. Shock. 2022;40(6):496–503. DOI: https://doi.org/10.1097/SHK.0000000000000066
Panigrahi P. A randomized synbiotic trial to prevent sepsis among infants in rural India. Nature. 2017;547(12):407. DOI: https://doi.org/10.1038/nature23480
Zhao YD. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2022; 8(8): p. CD006895. DOI: https://doi.org/10.1002/14651858.CD006895.pub4
Debnath N, Kumar A, Yadav AK. Probiotics as a biotherapeutics for the management and prevention of respiratory tract diseases. Microbiol Immunol. 2022;66:277–91. DOI: https://doi.org/10.1111/1348-0421.12980
Claassen-Weitz S, Lim KYL, Mullally C, Zar HJ, Nicol MP. The association between bacteria colonizing the upper respiratory tract and lower respiratory tract infection in young children: a systematic review and meta-analysis. Clin Microbiol Inf. 2021;27:1262–70. DOI: https://doi.org/10.1016/j.cmi.2021.05.034
Chakraborty M, Munshi S. The prospects of employing probiotics in combating COVID-19. Tzu Chi Med J. 2022;34:148–59. DOI: https://doi.org/10.4103/tcmj.tcmj_104_21
Horvath A, Habisch H, Prietl B, Pfeifer V, Balazs I, Kovacs G, et al. Alteration of the gut–lung axis after severe COVID-19 infection and modulation through probiotics: a randomized, controlled pilot study. Nutrients . 2024;16(22):46. DOI: https://doi.org/10.3390/nu16223840
Guarner, Sanders ME, Hania , Cohen. Probióticos y prebióticos. Organización Mundial de Gastroenterología. 2023 febrero.22.-Rodríguez Pascual , Sen de la Cruz Ldl, Amorós Villaverde , Perea Fuentes. Seguridad en el empleo de probióticos. Sociedad Española de Microbiota, Probióticos y Prebióticos. 2024;5(1):143-5.
Snydman DR. The safety of probiotics, clinical infectious diseases. Clin Infect Dis. 2023;46:376. DOI: https://doi.org/10.1086/523331
Ortega MA, Quintero IA. La aplicación de los probióticos en el cáncer: una actualización. Sanum. 2024;8(3):86-101.
Espín JB. Evidencias sobre probióticos. Comité científico del congreso actualización en pediatria. 2023;3:33-44.
Hamza MSD, Waydande SD, Shinde AD, Mhaske NSDP, Shinde SD. Pre and Probiotics In Paediatrics. VIMS Health Sci J. 2023;10(2):65. DOI: https://doi.org/10.46858/vimshsj.10208
Arrieta MC, Stiemsma LT, Amenyogbe N, Brown E, Finlay B. The intestinal microbiome in early life: health and disease. Front Immunol. 2014;4:27. DOI: https://doi.org/10.3389/fimmu.2014.00427
Berdi M, Lauzon-Guillain B, Forhan A, Castelli F, Fenaille F, Charles M. Componentes inmunitarios de la leche materna temprana: asociación con factores maternos y con alergia alimentaria notificada en la infancia. Pediatric Aller Immunol. 2019;30(1):43. DOI: https://doi.org/10.1111/pai.12998
Adjibade M, Davisse-Paturet C, Divaret-Chauveau A, Adel-Patient K, Raherison C, Dufourg M, et al. Enriquecimiento de la fórmula con probióticos o prebióticos y riesgo de infecciones y enfermedades alérgicas hasta los 5,5 años de edad en la cohorte nacional de ELFE. J Nutr. 2022;34(4):679.
Franka N, Orenci U, Joaquin A, Palencia J, Varea V, Theis S, et al. Long-Term Safety and Efficacy of Prebiotic Enriched Infant Formula—A Randomized Controlled Trial. Nutrients. 2021;13(4):780. DOI: https://doi.org/10.3390/nu13041276
Wargo WF. The history of infant formula: Quality, safety and standard methods. J AOAC International. 2016;64(1):877. DOI: https://doi.org/10.5740/jaoacint.15-0244
Brown KH, de Romaña D, Arsenault J, Peerson J, Penny M. Comparison of the effects of zinc delivered in a fortified food or a liquid supplement on the growth, morbidity and plasma zinc concentrations of young Peruvian children. American J Clin Nutr. 2007;45(2):7483. DOI: https://doi.org/10.1093/ajcn/85.2.538
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