Exceptional remission in laryngeal synovial sarcoma: a unique case treated with single-modality IMRT- Ranchi tertiary care centre experience

Satish Sharma; Anamika Kumari; Abhimanyu Kadapathri; Aftab Alam; Priyanka Singh; Vijay Tiwari

doi:10.18203/2320-6012.ijrms20251341

Authors

Satish Sharma HCG - Abdur Razzaque Ansari Cancer Hospital, Ibra, Jharkhand, India
Anamika Kumari Department of Radiation Oncology, RJSP Cancer Hospital, Ranchi, Jharkhand, India
Abhimanyu Kadapathri HCG - Abdur Razzaque Ansari Cancer Hospital, Ibra, Jharkhand, India
Aftab Alam HCG - Abdur Razzaque Ansari Cancer Hospital, Ibra, Jharkhand, India
Priyanka Singh HCG - Abdur Razzaque Ansari Cancer Hospital, Ibra, Jharkhand, India
Vijay Tiwari HCG - Abdur Razzaque Ansari Cancer Hospital, Ibra, Jharkhand, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20251341

Keywords:

Laryngeal synovial sarcoma, Intensity-modulated radiation therapy, Cytokeratin, Soft tissue tumor, Spindle cell sarcoma, BCL-2

Abstract

Laryngeal synovial sarcoma is an extremely rare cancer originating from smooth muscle cells predominantly found in the extremities. It is uncommon in the head and neck, with laryngeal involvement particularly rare, making accurate diagnosis challenging. This case report follows the journey of a 32-year-old female patient diagnosed with laryngeal synovial sarcoma. Notably, the patient underwent an unconventional treatment using only intensity-modulated radiation therapy (IMRT). Surprisingly, the patient achieved complete remission at the one-year follow-up, making this case exceptionally rare. It is noteworthy as one of the few instances where a single treatment modality, specifically IMRT, successfully led to complete remission in laryngeal synovial sarcoma treatment.

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