DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20150162

Patient based factors influencing drug compliance among hypertensive patients in a tertiary care hospital in Mysore

Shrinivasa BM, Kavita Yadav, Narayana Murthy MR, Kavitha HS

Abstract


Background: Hypertension is deemed as the tip of the iceberg due to the mortality and morbidity associated with it. A major factor accounting for inadequate treatment of hypertension is poor compliance.

Methods: Morisky 8-Item Medication Adherence Questionnaire was used for a cross sectional study. The term compliance is defined as the extent to which the patient’s behaviour coincides with the clinical prescription, implying that the patient defaults by not following the advice of the health care provider

Results: Mean age of the participants was 59.2yrs (S.D. 10.37 yrs). Compliance was found to be good 71.3% of respondents, medium in 20.4% and poor in 8.3%.52.8% had one or two other ailments (diabetes, asthma etc.).

Conclusions: Patient’s medication compliance is a multifactor behaviour in which the role of patient’s attitude is very important. Patients related factors known to affect compliance were equally distributed among good, medium and poorly compliant participants


Keywords


Hypertension, Adherence, Drug compliance

Full Text:

PDF

References


Saseen JJ. Essential Hypertension. In: Applied Therapeutics: The clinical use of drugs, 9th ed. Eds. Kode-kimble MA, et al. Lippincott Williams and Wilkins USA 2009, pp.314.

Ezzati M, Lopez A, Rodgers A, Vander Hoorn S, Murray C. Selected major risk factors and global and regional burden of disease. Lancet 2002; 360: 1347–1360

World Health Organization. Chapter III Hypertension in Adherence to Long-Term Therapies-Evidence for Action. 2003. p. 27. Available: http://www.who.int/ chronic_conditions/ adherencereport/ en/print.html. Accessed August 2005.

Berenson GS, et al. (1998) Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 338: 1650–1656.

Thompson DW, Furlan AJ (1996) Clinical epidemiology of stroke. NeurolClin 14: 309-315.

Adherence to Long-Term Therapies Evidence for action World Health Organization. 20 Avenue Appia, 1211 Geneva 27, Switzerland 2003.

Luscher T.F., Vetter H., Siegenthaler W and Vetter W., Compliance in hypertension: facts and concepts. JHypertens Suppl. 1985 Apr; 3(1): 3-9.

Thinking Outside the Pillbox: A System-wide Approach to Improving Patient Medication Adherence for Chronic Disease [full report; PDF file on the Internet]. NEHI Publication. 2009 Aug [cited May 2012]. Available from: http://www.nehi. net/publications/44/thinking_outside_the_pillbox_a_systemwide_approach_to_improving_patient_medication_adherence_for_chronic_disease. Accessed May 27, 2012.

Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, et al. (2005). Global burden of hypertension: analysis of worldwide data. Lancet 365: 217–23.

Roland NnaemekaOkoro,Cyprain Kingsley Ngong. Assessment of patient’s antihypertensive medication adherence levelin non-comorbid hypertension in a tertiary hospital in Nigeria. Int J Pharm Biomed Sci 2012, 3(2), 47-54.

Hashmi SK, Afridi MB, Abbas K, Sajwani RA, Saleheen D, et al (2007) Factors Associated with Adherence to Anti-Hypertensive Treatment inPakistan. PLoS ONE 2(3): e280. doi:10.1371/ journal.pone.0000280.

Khalil SA, Elzubier AG. Drug compliance among hypertensive patients in Tabuk, Saudi Arabia.J Hypertens.1997; 15: 561 – 565.

Blackwell B, Gutman MC. Compliance. In: Bulpitt CJ, ed. Epidemiology of Hypertension. Amsterdam; New York: Elsevier; New York, NY: Sole distributors for the USA and Canada, Elsevier Science; 1985: 453.

Balkrishnan R. Predictors of medication adherence in the elderly. ClinTher. 1998;20(4):764–771.

Degli-Esposti E, Sturani A, Di Martino M, et al. Long-term persistence with antihypertensive drugs in new patients. J Hum Hypertens. 2002; 16: 439 – 444.

Miller NH, Hill M, Kottke T, Ockene IS. The multilevel compliance challenge: recommendations for a call to action. A statement for health-care professionals. Circulation.1997; 95: 1085 – 1090.

Kaveh K, Kimmel PL. Compliance in hemodialysis patients: multidimensional measures in search of a gold standard. Am J Kidney Dis. 2001; 37: 244 –266.

Poor adherence to long-term treatment of chronic diseases is a worldwide problem. Pan Am J Public Health 2003; 14: 218-2.