A retrospective study of drug prescribing pattern in burns patients in a tertiary care rural hospital


  • Palak Agrawal Third year Resident, Department of Pharmacology, SBKSMI & RC, Piparia, Vadodara, Gujarat
  • Jaimin Patel Third year Resident, Department of Pharmacology, SBKSMI & RC, Piparia, Vadodara, Gujarat
  • P. S. Karelia Professor, Department of Pharmacology, SBKSMI & RC, Piparia, Vadodara, Gujarat




Burns, Antibiotics, Polypharmacy, Analgesics, Tetanus


Background: To study and describe the prevailing prescription trend in burns patients in a tertiary care rural hospital.

Methods: This was a retrospective observational study. Total 100 patients diagnosed with burn injury and admitted during Jan 2012 to Dec 2013 were included in the study. The demographic details, details of burn injury & treatment received were obtained from the medical record section of Dhiraj General Hospital, Piparia. Drug prescriptions were analyzed using Microsoft Excel for total number of drugs per prescription, various classes of drugs prescribed and group of antibiotics commonly prescribed.

Results: Most common age group affected was 20-40 years. The female to male ratio was 1.8:1. Average number of drugs prescribed was 6.8 with a range of 4-9 drugs per prescription. All prescriptions (100%) contain antimicrobials, analgesics and antiulcer drugs. Among antimicrobials, ceftriaxone was most commonly prescribed followed by amikacin and amoxicillin + clavulanic acid. Only 18% patients were immunized against tetanus.

Conclusions: Females are more vulnerable to burn injuries. Polypharmacy was observed in prescriptions. Systemic antibiotic should be used with caution to prevent emergence of resistant microorganisms. Results of the present study indicate that some aspects of drug treatment need to be rationalized in order to achieve better patient care.



Shehan Hettiaratchy, Peter Dziewulski - ABC of burns Introduction, BMJ 2004; 328:145-149.

M. Masellis, “Thermal agent disaster and fire disaster: definition, damage, assessment and reliefoperation,” in The Management of Mass Burns Casualties and Fire Disaster: Proceedings of the 1st International Conference in Burns and Fire Disasters, M. Masellis and S. W. A. Gunn, Eds. Kluwer Academic Publishers, Dordrecht, The Netherlands, 1992:7-12.

Norman S. Williams, Christopher J. K. Bulstrode and P. Roman O'connell : Burn injury. In: Bailey and Love's Short practice of surgery, 25th edition. New York, NY: Edward Arnold (Publishers) Ltd; 2008: 279-280.

World Health Organisation. Fact sheet May 2014 (Online) Available from http://www.who.int/ mediacentre/factsheets /fs365/en/index.html.

World Health Organisation. Fact sheet May 2012 (Online) Available from http://www.who.int/ mediacentre/factsheets /fs365/en/index.html.

Muqim R, Zareen M, Dilbag, Hayat M. Epidemiology and outcome of Burns at Khyber Teaching Hospital Peshawar. Pakistan Journal of Medical Sciences 23(3); 2007: 420-24.

I. Feller, D. Tholen, and R. G. Cornell, “Improvements in burn care, 1965 to 1979,” Journal of the American Medical Association, 244 (18), 1980: 2074–2078.

M. Choiniere, M. Dumont, J. Papillon, and D. R. Garrel, “Prediction of death in patients with burns,” The Lancet,353 (9171), 1999: 2211–2212.

B. S. Atiyeh, R. Dham, M. Kadry, et al., “Benefit-cost analysis of moist exposed burn ointment,” Burns, 28, (7), 2002 : 659–663.

P. Cornish, N. Mittmann, M. Gomez, R. C. Cartotto, and J.S. Fish, “Cost of medications in patients admitted to a burn center,” American Journal of Clinical Dermatology, 4 (12), 2003: 861–867.

Forjuoh SN. Burns in low- and middle-income countries: a review of available literature on descriptive epidemiology, risk factors, treatment, and prevention. Burns 2006; 32:529.

Peck MD, Kruger GE, van der Merwe AE, et al. Burns and fires from non-electric domestic appliances in low and middle income countries

Part I. The scope of the problem. Burns ; 34, 2008: 303.

Murray CJL, Lopez, AD. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020, World Health Organization, Swizerland 2006.

Subrahmanyan M, Joshi AV. Analysis of burn injury treated during a one year period at a district hospital in India. Annals of Burns and fire disaster 2003; 16 (2): 1-3.

Jeevangi SR, Patil RB, Awanti SM, Manjunath S, Patil B, Devi K. Drug utilization study in a burn care unit of a tertiary care hospital. Asian Pacific Journal of Tropical Disease ; 5(1): 2012; 41-46.

Padwal SL,Motghare VM, Kulkarni MD, Jadhav RR, Deshmukh VS, Drug Utilization in burn patients admitted in wards of a rural tertiary

care teaching hospital, International journal of pharmacology and therapeutics, 3 (3);2013:19-23.

Gendel J, Azzam ZS, Braun E Levyy, Krivoy N. Antibiotic utilization prevalence prospective comparison between two medical department in a tertiary care University hospital. Pharmacoepidemiol Drug Saf, 13; 2004: 735-739.

Avni T, Levcovich A, Ad El DD, Leibovici L, Paul M. Prophylactic antibiotics for burns patients: systematic review and meta-analysis. BMJ 2010; 340: 241.

Barajas Nava LA, López-Alcalde J, Roqué I Figuls M, Solà I, Bonfill Cosp X,Antibiotic prophylaxis for preventing burn wound infection. Cochrane Database Syst Rev. 2013 Jun 6;6:CD008738.

Dacso CC, Luterman A, Curreri PW. Systemic antibiotic treatment in burned patients.1987 Feb;67(1): 57-68.

Ravat F, Le-Floch R, Vinsonneau C, Ainaud P, Bertin-Maghit M, Carsin H, Perro G; Société Française d'Etude et de Traitement des Brûlures (SFETB). Antibiotics and the burn patient. Burns 2011 Feb; 37(1):16-26.

Marshall J H, Bromberg B E, Adrizzo J R, Heurich A E, Samet C M. Fatal tetanus complicating a small partial-thickness burn. J Trauma,1972;12:91–93. [PubMed].

Mozingo DW, McManus AT, Pruitt BA Jr (1998) Infections of burn wounds. In: Bennet JV, Brachman PS, (eds) Hospital Infections. 4th ed. Lippincott-Raven, Philadelphia, 587–597.

Fadaak H.A. Gastrointestinal haemorrhage in burn patients the experience of a burns unit in SaudiArabia Division of Plastic Surgery, King Fahd Hospital of the University, AI-Khobar, Saudi Arabia. Annals of Burns and Fire Disasters - vol. XIII - n. 2 – June 2000.

Fakhry SM, Alexander J, Smith D. Regional and Institutional variation in burn care. J Burn Care Rehabil. 1995;16:86–90.

Pham T, Cancio LC, Gibran NS. American Burn Association practice guidelines burn shock resuscitation. J Burn Care and Res. 2008; 29:257–66.

Loeser, J. (Ed.) Bonica's Management of Pain (3rd Ed.). Philadelphia, PA: Lippincot, Williams & Wilkins. 2001.

Molnar, J.A., Bell, S.J., Goodenough, R.D., and Burke, J.F.: Enteral nutrition in patients with burns or trauma. In: Rombeau, J.L. and Caldwell, M.D., eds. Enteral and Tube Feeding. Vol. 1. Philadelphia, PA: W.B. Saunders; 1984: 421-423.




How to Cite

Agrawal, P., Patel, J., & Karelia, P. S. (2017). A retrospective study of drug prescribing pattern in burns patients in a tertiary care rural hospital. International Journal of Research in Medical Sciences, 3(6), 1446–1452. https://doi.org/10.18203/2320-6012.ijrms20150165



Original Research Articles