Effect of high protein intervention on royal free hospital nutrition prioritising tool scores in patients with decompensated liver cirrhosis: a randomised control trial

Shobha; M. Madhavi Reddy; Prabhakar; Nitin Rao

doi:10.18203/2320-6012.ijrms20252026

Authors

Shobha Department of Clinical Nutrition and Dietetics, Sri Devaraj URS Academy of Higher Education and Research Kolar, Tamaka, Karnataka, India
M. Madhavi Reddy Department of Clinical Nutrition and Dietetics, Sri Devaraj URS Academy of Higher Education and Research Kolar, Tamaka, Karnataka, India
Prabhakar Department of General Medical, Sri Devaraj URS Academy of Higher Education and Research, Kolar, Tamaka, Karnataka, India
Nitin Rao Department of Surgical Gastroenterology, M S Ramaiah Hospitals Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20252026

Keywords:

High protein, Liver cirrhosis, Royal free hospital nutrition prioritizing tool, Randomised controlled trial, Serum albumin and ascites, Nutrition screening tool

Abstract

Background: The Royal Free Hospital Nutrition Prioritising Tool (RFH-NPT) is an effective instrument for assessing the nutritional status of individuals suffering from cirrhosis, demonstrating high sensitivity and specificity in detecting malnutrition risk among patients with liver cirrhosis.

Methods: 110 male patients with decompensated cirrhosis were randomized, to a standard diet and a peptide supplement. The nutrition prioritizing tool, royal free hospital nutrition prioritising tool (RFH-NPT) was used to assess the effects on anthropometrics, dietary and biochemical markers. The statistically significance were analysed at p<0.05.

Results: The peptide group showed significant improvement in nutrition tool scores, malnutrition and body mass index compared with controls (0.64±1.20 vs. 4.76±1.70, p<0.00 at 95% CI).

Conclusions: The RFH-NPT is a valuable tool for identifying cirrhosis patients at risk of malnutrition, thereby allowing patients to receive nutritional care to improve their nutritional status and overall clinical outcomes.

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