Diagnostic concordance of ultrasound and histopathology in pediatric neck masses

Authors

  • Mahmuda Monowara Department of Radiology and Imaging, Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh
  • Mashud Parvez Department of Histopathology, Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh
  • Shakila Jannat Department of Histopathology, Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20252385

Keywords:

Ultrasound, Histopathology, Neck masses, Pediatric

Abstract

Background: Ultrasonography has become the most accessible, safe, and cost-effective imaging modality for evaluating pediatric neck masses, especially in resource-limited settings. The purpose of the study was to assess the diagnostic concordance between ultrasound findings and histopathological results in pediatric neck masses. The aim of the study was to evaluate the diagnostic concordance between ultrasound findings and histopathological results in pediatric neck masses.

Methods: This observational diagnostic study was conducted at Bangladesh Shishu hospital and institute from October 2023 to March 2025, involving 550 children (0-12 years) with palpable neck masses. All cases underwent ultrasound and confirmatory histopathological examination. Diagnoses were made independently by radiologists and blinded pathologists. Concordance was defined as an exact diagnostic match. Data were analyzed using SPSS v28 with descriptive statistics.

Results: Among 550 pediatric patients with neck masses, most were aged >2-5 years (50.9%) with a balanced gender distribution. Lymphadenitis was the most common ultrasound (40.6%) and histopathological (34.2%) finding. Congenital lesions like cystic hygromas, thyroglossal duct cysts, and haemangiomas were also frequent. Ultrasound showed high diagnostic concordance, particularly for cystic hygromas (98.0%), thyroglossal duct cysts (97.7%), and branchial cleft cysts (96.2%), with an overall concordance rate of 90.0%.

Conclusions: Ultrasound demonstrates high concordance with histopathology, reinforcing its value as a reliable, non-invasive first-line diagnostic tool for pediatric neck masses.

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References

Albright JT, Topham AK, Reilly JS. Pediatric head and neck malignancies: US incidence and trends over 2 decades. Arch Otolaryngol Head Neck Surg. 2002;128(6):655-9. DOI: https://doi.org/10.1001/archotol.128.6.655

Unsal O, Soytas P, Hascicek SO, Coskun BU. Clinical approach to pediatric neck masses: Retrospective analysis of 98 cases. Northern Clin İstanbul. 2017;4(3):225. DOI: https://doi.org/10.14744/nci.2017.15013

Okasha HH, El-Amin H, Sayed ZE, Maghraby AA. Role of Endoscopic Ultrasound Elastography Strain Histograms in the Evaluation of Patients with Pancreatic Masses. Turk J Gastroenterol. 2021;32(6):519. DOI: https://doi.org/10.5152/tjg.2021.20678

Osifo OD, Ugiagbe EE. Neck masses in children: Etiopathology in a tertiary center. Niger J Clin Pract. 2011;14(2):232-6. DOI: https://doi.org/10.4103/1119-3077.84027

Al-Khateeb TH, Al Zoubi F. Congenital neck masses: a descriptive retrospective study of 252 cases. J Oral Maxillofac Surg. 2007;65(11):2242-7. DOI: https://doi.org/10.1016/j.joms.2006.11.039

Turkington JR, Paterson A, Sweeney LE, Thornbury GD. Neck masses in children. Brit J Radiol. 2005;78(925):75-85. DOI: https://doi.org/10.1259/bjr/15273006

Maharjan M, Hirachan S, Kafle PK, Bista M, Shrestha S, Toran KC, et al. Incidence of tuberculosis in enlarged neck nodes, our experience. Kathmandu University Med J. 2009;7(1):54-8. DOI: https://doi.org/10.3126/kumj.v7i1.1766

Torsiglieri AJ Jr, Tom LW, Ross AJ III: Pediatric neck masses: Guidelines for evaluation. Int J Pediatr Otorhinolaryngol. 1988;16:199-210. DOI: https://doi.org/10.1016/0165-5876(88)90031-6

Diaz A, Tringler M, Galli C, Ramirez A, Fischer EI. Arterial stiffness in a rural population of Argentina: pilot study. High Blood Press Cardiovas Prevent. 2015;22:403-9. DOI: https://doi.org/10.1007/s40292-015-0110-7

Malik A, Odita J, Rodriguez J, Hardjasudarma M. Pediatric neck masses: a pictorial review for practicing radiologists. Curr Prob Diagnost Radiol. 2002;31(4):146-57. DOI: https://doi.org/10.1067/cdr.2002.125778

Swischuk LE, John SD. Neck masses in infants and children. Radiologic Clin N Am. 1997;35(6):1329-40. DOI: https://doi.org/10.1016/S0033-8389(22)00729-1

Meuwly JY, Lepori D, Theumann N, Schnyder P, Etechami G, Hohlfeld J, et al. Multimodality imaging evaluation of the pediatric neck: techniques and spectrum of findings. Radiographics. 2005;25(4):931-48. DOI: https://doi.org/10.1148/rg.254045142

Gov-Ari E, Hopewell BL. Correlation between pre-operative diagnosis and post-operative pathology reading in pediatric neck masses-A review of 281 cases. Int J Pediat Otorhinolaryngol. 2015;79(1):2-7. DOI: https://doi.org/10.1016/j.ijporl.2014.11.011

Debajit S, Summy S, Manaswi S, Rahul C. Clinicopathological study of neck masses in children. Int J Pharm Clin Res. 2024;16(3):723-30.

Al-Mayoof AF. Neck masses in paediatric population: An experience with children attended the Central Teaching Hospital of Pediatrics in Baghdad 2008-2009. Afr J Paediatr Surg. 2015;12(2):136-9. DOI: https://doi.org/10.4103/0189-6725.160364

Lucumay EM, Gilyoma JM, Rambau PF, Chalya PL. Paediatric neck masses at a university teaching hospital in northwestern Tanzania: a prospective analysis of 148 cases. BMC Res Not. 2014;7:1-7. DOI: https://doi.org/10.1186/1756-0500-7-772

Shuaibu IY, Sholadoye TT, Ajiya A, Usman MA, Aliyu HO. Paediatric neck masses in Zaria: A review of clinical profile and treatment outcome. Afr J Paediatr Surg. 2021;18(4):205-9. DOI: https://doi.org/10.4103/ajps.AJPS_134_20

Gangwar N, Vyas P, Gakkar S. Clinicopathological study of pediatric neck masses. Int J Otorhinolaryngol Head Neck Surg. 2018;4(2):343. DOI: https://doi.org/10.18203/issn.2454-5929.ijohns20180504

Gupta A, Ukawat L, Nagar V, Singh A. Clinico-pathological study of paediatric neck masses in a tertiary care hospital of central India. Int J Med Health Res. 2020;6(1):92-94.

Shahabuddin MD, Singh SK. Role of ultrasonography in the evaluation of pediatric neck masses in a rural population: A 12-month observational study at JLNMCH, Bhagalpur. Int J Curr Pharm Rev Res. 2024;16(12):610-5.

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Published

2025-07-30

How to Cite

Monowara, M., Parvez, M., & Jannat, S. (2025). Diagnostic concordance of ultrasound and histopathology in pediatric neck masses. International Journal of Research in Medical Sciences, 13(8), 3203–3207. https://doi.org/10.18203/2320-6012.ijrms20252385

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Original Research Articles