Perforator flaps in soft tissue reconstruction: clinical outcomes in reconstructive plastic surgery

Authors

  • Manuel Cabrera Charleston Department of Surgery, General Hospital of Mexico, Mexico City, Mexico
  • Daniela Guadalupe Oscura Paredes Department of Internal Medicine, Medica Sur Hospital, Mexico City, Mexico
  • Miguel Angel Lara Sanchez Department of Surgery, General Hospital of Mexico, Mexico City, Mexico

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253180

Keywords:

Perforator flaps, Soft tissue reconstruction, Reconstructive plastic surgery, Surgical technique, PRISMA

Abstract

Perforator flaps constitute a significant advancement in soft tissue reconstruction within reconstructive plastic surgery, relying on perforator vessels that supply the skin and subcutaneous tissue without requiring large muscle or fascia volumes. This innovative approach allows for more refined and less invasive reconstructions, preserving muscular integrity and reducing functional deficits at the donor site. These flaps have become increasingly important in the management of complex defects resulting from oncologic resections, traumatic injuries, or chronic wounds particularly in anatomically complex regions. Advances in preoperative imaging and intraoperative navigation have enhanced the accuracy of flap planning and reduced complication rates. Additionally, the evolution of flap design-such as propeller, free-style, and supermicrosurgical flaps-has expanded reconstructive options. This systematic review aimed to evaluate recent innovations, surgical techniques, and clinical outcomes associated with perforator flaps across a range of reconstructive scenarios. A total of 30 studies were included, comprising clinical trials and observational research focusing on different anatomical sites (extremities, head and neck, breast, and trunk). The findings reveal a flap survival rate ranging from 93% to 98%, lower complication rates compared with conventional musculocutaneous methods, and high patient satisfaction. Nevertheless, heterogeneity in outcome measures and lack of randomized studies with large sample sizes underscore need for more standardized protocols and multicenter research to draw stronger conclusions.

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References

Kroll SS. Prefabricated and prelaminated flaps for head and neck reconstruction. Clin Plast Surg. 2013;40(3):729-35.

Taylor GI, Palmer JH. The vascular territories (angiosomes) of the body: experimental study and clinical applications. Br J Plast Surg. 1987;40(2):113-41. DOI: https://doi.org/10.1016/0007-1226(87)90185-8

Koshima I, Soeda S. Inferior epigastric artery skin flaps without rectus abdominis muscle. Br J Plast Surg. 1989;42(6):645-8. DOI: https://doi.org/10.1016/0007-1226(89)90075-1

Blondeel PN, Morris SF, Hallock GG, Neligan PC. Perforator flaps: anatomy, technique and clinical applications. St. Louis: Quality Medical Publishing; 2013.

Wei FC, Jain V, Celik N, Chen HC, Chuang DC, Lin CH. Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps. Plast Reconstr Surg. 2002;109(7):2219-26. DOI: https://doi.org/10.1097/00006534-200206000-00007

Rozen WM, Ashton MW, Grinsell D. The perforator angiosome: a new concept in flap design. ANZ J Surg. 2011;81(6):456-62.

Teo TC. Perforator local flaps in lower limb reconstruction. Cir Plast IberLatinoam. 2015;41(3):177-86.

Zhong T, Cheng A, Nhuyen D, Odobescu A, Antony A, Hofer SO. Outcomes and complications of perforator flap breast reconstruction: a systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2014;67(12):1615-30.

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ. 2009;339:b2535. DOI: https://doi.org/10.1136/bmj.b2535

Hallock GG. The utility of both perforator flaps and musculocutaneous flaps in reconstruction of the lower extremity. Plast Reconstr Surg. 2006;117(4):151S-7S.

Yazar S. Selection of recipient vessels in microsurgical free tissue reconstruction of the lower extremity. J Reconstr Microsurg. 2007;23(5):231-9.

Panse N, Sahashrabudhe P, Tandale MS. Algorithmic approach to the planning of a perforator flap. Indian J Plast Surg. 2013;46(2):365-71.

Kim JT, Seo KJ. Perforator flap vs conventional flap. J Reconstr Microsurg. 2014;30(7):467-75. DOI: https://doi.org/10.1055/s-0034-1370358

Wei FC, Mardini S, Lin CH. Free-style free flaps. Plast Reconstr Surg. 2003;112(3):9-10.

Saint-Cyr M, Schaverien M, Rohrich RJ. Perforator flaps: history, controversies, physiology, and anatomy. Plast Reconstr Surg. 2009;123(4):132-45. DOI: https://doi.org/10.1097/PRS.0b013e31819f2c6a

Li S, Chang T, Chen S, Chen T, Tsai F, Chen S. The anterolateral thigh flap: variations in vascular pedicle and anatomy. J Plast Reconstr Aesthet Surg. 2009;62(5):499-504.

Georgescu AV. Prefabricated perforator flaps: a 10-year experience. Microsurgery. 2016;36(2):86-93.

Choi DH, Oh DY, Lee JS, Jeon MK, Shin YA, Kim JY. Clinical applications of thoracodorsal artery perforator flaps in reconstruction surgery. Plast Reconstr Surg. 2015;136(4):59-66.

Maldaun MVC, Prucz R, Kuo YR, Chen HC. The reliability of anterolateral thigh flap perforators. Microsurgery. 2010;30(2):95-102.

Schaverien M, Saint-Cyr M. Perforators of the DIEP flap: importance of preoperative mapping and venous congestion. Plast Reconstr Surg. 2008;121(3):591-7. DOI: https://doi.org/10.1097/PRS.0b013e31816b1479

Banchini P, Bortolotto C, Siliprandi M, Ferrara F, Salgarello M. Risk factors for complications in free flap breast reconstruction. Eur Rev Med Pharmacol Sci. 2019;23(2):87-94.

Seidenstuecker K, Munder BI, Mahajan AL, Laminger KA, Lohlein H, Harder Y. Postoperative complications in perforator flap breast reconstruction: how relevant is the learning curve? A single surgeon’s experience of 1000 DIEP/TMG flaps. J Plast Reconstr Aesthet Surg. 2011;64(1):59-67.

Güven E, Çiçek T, Kontaş O. Reliability of perforator flaps in extremity reconstruction. Microsurgery. 2021;41(5):431-7.

Ribuffo D, Atzeni M, Saba L, Guerra M, Lisai P, Gerardi C, et al. The anterolateral thigh flap in head and neck reconstruction: reliability and timing of thinning. J Plast Reconstr Aesthet Surg. 2014;67(2):163-9.

Pang W, Carter LM, Birchall MA, Rhodri SW, Clarke PM, Shenoy V. Complications associated with perforator flaps in the lower limb. J Plast Surg Hand Surg. 2019;53(3):143-9.

Gravvanis AI, Karakitsos D, Lagopoulos VI, Tsoutsos D, Iconomou T. Evaluation of microcirculation in perforator flaps with contrastenhanced ultrasound. J Reconstr Microsurg. 2012;28(2):145-50.

Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. DOI: https://doi.org/10.1136/bmj.d5928

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Lancet. 2007;370(9596):1453-7. DOI: https://doi.org/10.1016/S0140-6736(07)61602-X

Hanson SE, Chim H, Yalanis GC, Rohde CH. Flap monitoring technology in microvascular reconstructive surgery: current concepts and new directions. J Reconstr Microsurg. 2013;29(6):351-6.

McGregor IA, Morgan G. Axial and random pattern flaps. Br J Plast Surg. 1973;26(3):202-13. DOI: https://doi.org/10.1016/0007-1226(73)90003-9

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Published

2025-09-29

How to Cite

Charleston, M. C., Oscura Paredes, D. G., & Lara Sanchez, M. A. (2025). Perforator flaps in soft tissue reconstruction: clinical outcomes in reconstructive plastic surgery. International Journal of Research in Medical Sciences, 13(10), 4290–4295. https://doi.org/10.18203/2320-6012.ijrms20253180

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Section

Systematic Reviews