Autoimmune pancreatitis in an adolescent female following dengue fever: a diagnostic challenge in IgG4-related disease

Authors

  • Sanjana J. P. Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, India https://orcid.org/0009-0000-2499-6269
  • Anis Preethi Aruldas Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, India
  • Viknesh Prabu Anbalagan Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20252810

Keywords:

Autoimmune pancreatitis, IgG4-related disease, Chronic pancreatitis, Dengue, Fever, Adolescent female

Abstract

Autoimmune pancreatitis (AIP), a rare form of chronic pancreatitis, is often misdiagnosed due to its overlap with other causes of pancreatic inflammation. We report an unusual case of an 18-year-old female who developed acute pancreatitis in the context of dengue fever. Persistent elevation of pancreatic enzymes and characteristic imaging led to further evaluation, confirming Type 1 AIP through elevated serum IgG4, weakly positive ANA, and histopathology. This case emphasizes the need for a comprehensive diagnostic approach to avoid delayed diagnosis and prevent irreversible organ damage.

Metrics

Metrics Loading ...

References

Nista EC, De Lucia SS, Manilla V, Schepis T, Pellegrino A, Ojetti V, et al. Autoimmune pancreatitis: from pathogenesis to treatment. International J Mol Sci. 2022;23(20):12667. DOI: https://doi.org/10.3390/ijms232012667

Thomas AS, Abreo M, Sayed SA, Yedururi YW, Chari ST. Autoimmune pancreatitis secondary to immune checkpoint inhibitor therapy (type 3 AIP): insights into a new disease from serial pancreatic imaging. Gastroenterology. 2023;164(1):154-5. DOI: https://doi.org/10.1053/j.gastro.2022.09.042

Vemulapalli V, Natha C, Shirwaikar Thomas A. Autoimmune Pancreatitis: A Review. J Clin Med. 2025;14(9):3076. DOI: https://doi.org/10.3390/jcm14093076

Matana Kaštelan Z, Brumini I, Poropat G, Tkalčić L, Grubešić T, Miletić D. Pancreatic iodine density and fat fraction on dual-energy computed tomography in acute pancreatitis. Diagnostics. 2024;14(9):955. DOI: https://doi.org/10.3390/diagnostics14090955

Yoon SB, Jeon TY, Moon SH, Lee SM, Kim MH. Systematic review and meta-analysis of MRI features for differentiating autoimmune pancreatitis from pancreatic adenocarcinoma. European Radiol. 2022;32(10):6691-701. DOI: https://doi.org/10.1007/s00330-022-08816-1

Downloads

Published

2025-08-29

How to Cite

J. P., S., Aruldas, A. P., & Anbalagan, V. P. (2025). Autoimmune pancreatitis in an adolescent female following dengue fever: a diagnostic challenge in IgG4-related disease. International Journal of Research in Medical Sciences, 13(9), 3869–3871. https://doi.org/10.18203/2320-6012.ijrms20252810

Issue

Section

Case Reports