Modified fourth generation autologous cartilage transplantation for grade 2-3 knee osteoarthritis
DOI:
https://doi.org/10.18203/2320-6012.ijrms20260978Keywords:
Knee osteoarthritis, Cartilage transplantation, NPRS, Autologous cartilage, Fourth-generation ACI, PRP, Arthroscopic surgeryAbstract
Osteoarthritis (OA) of the knee poses a significant burden on physical mobility and quality of life, especially in middle-aged adults. This study evaluates the outcomes of a modified fourth-generation autologous cartilage transplantation technique developed to overcome limitations of traditional cartilage repair strategies. The major learning curve observed during this study was that patient preferred a minimally invasive and a shorter hospital stay technique over traditional TKR. The case series involves a cohort of 15 patients with Grade 2-3 knee OA, the case series showed significant improvements in pain relief, knee function, early mobilization, and patient satisfaction with no reported adverse events. Some patients had follow-up data extending up to 5 years, with results consistent with 6-month outcomes. Improved patient mobility score and improved patient satisfaction score noted. This technique offers a cost-effective, single-stage, arthroscopic alternative with promising short- and mid-term outcomes. Thus, this technique caters to the population at early osteoarthritis stage preventing an Early replacement.
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