Prompt diagnosis and treatment of cutaneous mucormycosis: a challenging complication in post-renal transplant patients
DOI:
https://doi.org/10.18203/2320-6012.ijrms20253204Keywords:
Amphotericin B, Acute tubular injury, Isavuconazole, Mucormycosis, Renal transplantAbstract
A 52 years old male cadaveric renal transplant recipient developed cutaneous mucormycosis, presenting with febrile toxicity and a rapidly growing black lesion. Diagnosis was confirmed by biopsy and treatment began with liposomal amphotericin B. Owing to the high mortality associated with mucormycosis, isavuconazole, a non-nephrotoxic antifungal, was added to Amphotericin B. The patient underwent surgical debridement and his condition subsequently stabilized, accompanied by improved renal function. He was discharged on a combination of isavuconazole and other medications, with good wound healing and a creatinine level of 1.6 mg/dl at one-month follow-up. This case highlights prompt diagnosis and treatment and maintenance with isavuconazole as a viable alternative for mucormycosis in transplant patients with renal impairment.
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