A rare gastric and peritoneal metastasis of cervical squamous cell carcinoma-an unusual breach and homing
DOI:
https://doi.org/10.18203/2320-6012.ijrms20253991Keywords:
Squamous cell, HPV, Gastric, Metastasis, PeritoneumAbstract
Gastric metastasis is rare with a reported incidence of less than 1% with only a very few case reports in the literature to date. Gastric metastasis most commonly arises from malignant melanoma. We present a case of a 58-year-old female, a case of metastatic poorly differentiated squamous cell carcinoma of cervix. Radiology showed a circumferential asymmetric enhancing wall thickening in antrum of stomach and peritoneal carcinomatosis. Endoscopy showed circumferential thickening in proximal antrum, biopsy of stomach and peritoneum showed carcinoma-possibly poorly differentiated squamous cell carcinoma which on immunohistochemistry (IHC) was confirmed to be HPV associated poorly differentiated squamous cell carcinoma. The patient was started on palliative chemotherapy and is on follow-up.
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References
Bray F, Ren JS, Masuyer E, Ferlay J. Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer. 2013;132(5):1133-45. DOI: https://doi.org/10.1002/ijc.27711
Gurian L, Ireland K, Petty W, Katon R. Carcinoma of the cervix involving the duodenum: case report and review of the literature. J Clin Gastroenterol. 1981;3(3):291-4. DOI: https://doi.org/10.1097/00004836-198109000-00015
Topuz OV, Bağbudar S. Cervical Cancer Metastasis to the Stomach Masquerading as Primary Gastric Cancer: A Case Report of a Rare Metastasis Detected via 18F-FDG PET/CT. Nuklearmedizin-Nuclear Med. 2024;63(03):221-3. DOI: https://doi.org/10.1055/a-2224-9673
Hasan F, Timsaal Y, Gandhi TV, Shojaei H, Schwartz M, Chaaya A. Rare Gastric Metastasis From Cervical Cancer: A Case Report. Clin Case Rep. 202513(2):e70181.
Langner C. Secondary tumors of the gastrointestinal tract. Der Pathologe. 2012;33:45-52. DOI: https://doi.org/10.1007/s00292-011-1544-x
Parks RE. Squamous neoplasms of the stomach. Am J Roentgenol. 1967;101(2):447-9. DOI: https://doi.org/10.2214/ajr.101.2.447
Maglica M, Dragisic V, Perutina I, Miskovic J. Gastric Perforation due to Cervical Cancer Metastasis. J Clin Pract Res. 2024;46(1):109. DOI: https://doi.org/10.14744/cpr.2024.33043
De Palma GD, Masone S, Rega M, Simeoli I, Donisi M, Addeo P, et al. Metastatic tumors to the stomach: clinical and endoscopic features. World J Gastroenterol. 2006;12(45):7326. DOI: https://doi.org/10.3748/wjg.v12.i45.7326
Oriuchi M, Uno K, Fujishima F, Takeuchi A, Lee S, Hatta W, et al. A rare case of gastric squamous-cell carcinoma metastasized from the cervix. Clin J Gastroenterol. 2020;13:1062-5. DOI: https://doi.org/10.1007/s12328-020-01191-8