Association of bone mineral density with sarcopenia indicators in the elderly population

Authors

  • Faisal Ahmed Bhuiyan Department of Medicine, Comilla Medical College Hospital, Cumilla, Bangladesh
  • Muhammad Asif Iqbal Department of Medicine, 250 Beded General Hospital, Chandpur, Bangladesh
  • M. Sherazul Islam Department of Blood Bank, Comilla Medical College Hospital, Cumilla, Bangladesh
  • Mohammad Mohibul Alam Department of Medicine, Upazila Health Complex Haziganj, Chandpur, Bangladesh
  • Hasina Akther Department of Pediatric Gastroenterology & Nutrition, Comilla Medical College Hospital, Cumilla, Bangladesh
  • M. Jahangir Alam Department of Medicine, Comilla Medical College Hospital, Cumilla, Bangladesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20254356

Keywords:

ASMMI, Bone mineral density, Osteoporosis, Sarcopenia

Abstract

Background: Osteoporosis and sarcopenia are age-related conditions that contribute to frailty, falls, and disability. The coexistence of osteopenia and sarcopenia, known as osteosarcopenia, is a growing concern.  This study investigated the association between bone mineral density (BMD) and sarcopenia in elderly patients with osteoporosis.

Methods: A hospital-based cross-sectional study was conducted at Cumilla Medical College Hospital, Bangladesh, from January 2020 to January 2021. A total of 100 elderly patients (≥60 years) with osteoporosis were enrolled. BMD was assessed using dual-energy X-ray absorptiometry. Sarcopenia was evaluated using the EWGSOP2 criteria, hand grip strength, appendicular skeletal muscle mass index (ASMMI), and the Timed Up and Go test (TUG). Data were analyzed using SPSS version 20.

Results: The mean age was 66±7 years, and 88% of the patients were female. Sarcopenia was present in 61% of patients and was more prevalent in patients with severe osteoporosis (72.4%). The mean lumbar spine and femoral neck T-scores were -3.29±1.04 and -3.09±1.56, respectively. The functional parameters included grip strength of 17.76±5.94 kg (right hand), walking speed of 0.65±0.12 m/s, and TUG of 13.5±3.2 seconds. Significant positive correlations were observed between ASMMI and BMD at the lumbar spine (r=0.264) and femoral neck (r=0.356) (p=0.008).

Conclusions: Reduced BMD was significantly associated with impaired sarcopenia indicators in elderly patients. Early identification and management of osteoporosis and sarcopenia are essential for preventing frailty and improving patient outcomes.

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Published

2025-12-30

How to Cite

Bhuiyan, F. A., Iqbal, M. A., Sherazul Islam, M., Alam, M. M., Akther, H., & Jahangir Alam, M. (2025). Association of bone mineral density with sarcopenia indicators in the elderly population. International Journal of Research in Medical Sciences, 14(1), 17–21. https://doi.org/10.18203/2320-6012.ijrms20254356

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Original Research Articles