Assessment of endothelial dysfunction in diabetes mellitus in Indian population by color Doppler


  • Abhilash Haridas Internal Medicine Resident NSCB Medical College Jabalpur, MP, Madhya Pradesh
  • Payal Mukker Internal Medicine Resident NSCB Medical College Jabalpur, MP, Madhya Pradesh
  • Sanjay Pandey Associate Professor, Department of Radiology NSCB Medical College Jabalpur, Madhya Pradesh
  • Manoj Kumar Parashar Professor, Department of Internal Medicine NSCB Medical College Jabalpur, Madhya Pradesh
  • Virender Kumar Mehta Head of the Department of Medicine (Retired) NSCB Medical College Jabalpur, Madhya Pradesh



Diabetes mellitus, Endothelial dysfunction, FMD, Atherosclerosis


Background: Endothelial dysfunction is regarded as a systemic marker of cardiovascular disease. Brachial artery flow-mediated dilation (FMD) is a mode of evaluating endothelial function and for early diagnosis of atherosclerotic diseases. We studied whether there is a difference in vascular endothelial function between type 1 and 2 diabetes mellitus and normal population.

Methods: We assessed %FMD of 50 patients with diabetes mellitus and 50 control populations without diabetes mellitus or other risk factors. SPSSS version 13 was used for statistical analysis. Students T test was used for comparison of means of the two groups.

Results: The %FMD was significantly lower in patients with type1 and 2 diabetes mellitus compared to normal population.

Conclusions: Diabetes mellitus is associated with endothelial dysfunction irrespective of Type 1 or Type 2 diabetes mellitus, as suggested by impairment in vascular reactivity to hyperemia in both. Monitoring FMD may help in assessment of progression of atherosclerosis.

Author Biography

Virender Kumar Mehta, Head of the Department of Medicine (Retired) NSCB Medical College Jabalpur, Madhya Pradesh

Virender Kumar Mehta


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How to Cite

Haridas, A., Mukker, P., Pandey, S., Parashar, M. K., & Mehta, V. K. (2016). Assessment of endothelial dysfunction in diabetes mellitus in Indian population by color Doppler. International Journal of Research in Medical Sciences, 4(9), 3956–3962.



Original Research Articles