Periodontitis and malignancy: a growing concern

Authors

  • Nanditha Chandran Department of Periodontics and Implantology, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India
  • Anil Melath Department of Periodontics and Implantology, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India
  • Subair Kayakool Department of Periodontics and Implantology, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India
  • Gokul Gopinath Department of Periodontics and Implantology, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India
  • Hamda Shahzadi Department of Periodontics and Implantology, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253653

Keywords:

Periodontitis, Microorganisms, Risk, Cancer

Abstract

Periodontitis is an inflammatory disease affecting the supporting structures of the tooth resulting in tooth mobility and tooth loss. Periodontitis has been consistently associated with a higher risk for head and neck cancer. Possible mechanisms include the chronic inflammatory nature of the disease, epigenetic damage to the epithelial cells by periodontal pathogens and dysbiosis. The present review focuses on various pathways of spread of head and neck cancers and the role of various periodontal pathogens in initiating this carcinogenesis.

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Published

2025-10-30

How to Cite

Chandran, N., Melath, A., Kayakool, S., Gopinath, G., & Shahzadi, H. (2025). Periodontitis and malignancy: a growing concern. International Journal of Research in Medical Sciences, 13(11), 5087–5089. https://doi.org/10.18203/2320-6012.ijrms20253653

Issue

Vol. 13 No. 11 (2025): November 2025

Section

Review Articles
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