Anemia and its determinants among adults in central India: a cross-sectional study

Authors

  • Aanchal Bijlwan Department of Community Medicine, RD Gardi Medical College, Ujjain, Madhya Pradesh, India
  • Sapna Rathore Department of Community Medicine, RD Gardi Medical College, Ujjain, Madhya Pradesh, India
  • Jagrati Bahrani Department of Community Medicine, RD Gardi Medical College, Ujjain, Madhya Pradesh, India
  • Nitin Bhargav Department of Community Medicine, RD Gardi Medical College, Ujjain, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20254362

Keywords:

Anemia, Body mass index, Hematological parameters, Hemoglobin, Nutritional status, Public health

Abstract

Background: Anemia remains a major public health problem in India despite national control programmes. Its multifactorial causes include nutritional deficiencies, chronic illnesses, and sociodemographic factors. Limited data are available on the interplay of anemia with nutritional status and hematological variations in central India.

Methods: A cross-sectional study was conducted among 392 participants. Demographic and anthropometric details were recorded, and BMI was classified using WHO Asian cut-offs. Hematological parameters (Hb, MCV, MCH, MCHC, hematocrit) were measured using an automated analyser. Anemia was defined and graded using WHO criteria and further classified morphologically. Statistical analysis included Chi-square test, Student’s t-test, ANOVA, and Pearson’s correlation. A p value <0.05 was considered significant.

Results: The mean hemoglobin level was 12.64±1.49 gm/dl. The prevalence of anemia was 36%, with 0.3% severe, 12.8% moderate, and 23% mild cases. Morphologically, microcytic anemia (24%) and hypochromic anemia (53.6%) predominated. Anemia was significantly associated with age (p=0.012), highest among participants <18 years (43.2%). No significant association was found with sex or BMI, though underweight individuals had the highest prevalence (43.8%). Mean hemoglobin was significantly higher in males (13.38 gm/dl) than females (12.22 gm/dl, p<0.001). Hemoglobin correlated positively with both BMI (r=0.159, p=0.002) and age (r=0.202, p<0.001).

Conclusions: Anemia affects more than one-third of the studied population, with microcytic and hypochromic patterns suggesting iron deficiency as a major cause. Younger individuals and those with low BMI are most vulnerable. The findings highlight the dual burden of malnutrition- anemia and undernutrition coexisting with rising overweight, obesity, and elevated blood sugar. Targeted interventions addressing both ends of the nutritional spectrum are urgently needed.

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References

Let S, Tiwari S, Singh A, Chakrabarty M. Prevalence and determinants of anemia among women of reproductive age in aspirational districts of India. BMC Public Health. 2024;241:17789. DOI: https://doi.org/10.1186/s12889-024-17789-3

Jeevan J, Karun KM, Puranik A, Deepa C, Mk L, Barvaliya M. Prevalence of anemia in India: a systematic review, meta-analysis and geospatial analysis. BMC Public Health. 2025;251:1270.

Government of Madhya Pradesh. Health Dossier 2021: Madhya Pradesh. NFHS-5 findings. Bhopal: Dept. of Health; 2021. Available from: https://nhsrcindia.org/sites/default/files/practice_image/HealthDossier2021/Madhya%20Pradesh.pdf. Accessed on 11 July 2025.

Times of India. 73% of kids aged 6-59 months in MP are anaemic, reveals NFHS-5. Times of India. 2022. Available from: https://timesofindia.indiatimes.com/ city/indore/73-of-kids-aged-6-59-months-in-mp-are-anaemic-reveals-nfhs-latest-data/articleshow/ 91674503.cms. Accessed on 11 July 2025.

Joshi P, Joseph D, Bajpai P, Manoria P, Joshi P, Yadav V. Prevalence of anemia among the general population of Malwa (MP), India. J Evol Med Dent Sci. 2013;21:44-9.

Ratre BK, Gajbhiye V, Sakharkar PR, Patil S. Clinical and epidemiological profile of anemia in central India. Int J Med Res Rev. 2014;21:57-61. DOI: https://doi.org/10.17511/ijmrr.2014.i01.09

International Institute for Population Sciences (IIPS) and ICF. National Family Health Survey (NFHS-5), 2019-21: India. Mumbai: IIPS; 2021. Available from: https://dhsprogram.com/pubs/pdf/FR375/FR375.pdf. Accessed on 11 July 2025.

Scott S, Lahiri A, Sethi V, de Wagt A, Menon P, Yadav K, et al. Anaemia in Indians aged 10-19 years: Prevalence, burden and associated factors at national and regional levels. Matern Child Nutr. 2022;18(4):e13391. DOI: https://doi.org/10.1111/mcn.13391

Jeevan J, Karun KM, Puranik A, Deepa C, Mk L, Barvaliya M. Prevalence of anemia in India: a systematic review, meta-analysis and geospatial analysis. BMC Public Health. 2025;25:1270. DOI: https://doi.org/10.1186/s12889-025-22439-3

Acharya SR, Timilsina D, Acharya S. Association between blood hemoglobin levels, anemia, and body mass index in children and women of Myanmar: findings from a nationally representative health study. Sci Rep. 2024;14(1):32020. DOI: https://doi.org/10.1038/s41598-024-83684-x

Chen Z. Association between obesity and anemia in a nationally representative sample: patterns and possible mechanisms. BMC Public Health. 2024;24:10965.

Alshwaiyat NM, Ahmad A, Wan Hassan WM, Al-Jamal HA. Association between obesity and iron deficiency. Exp Ther Med. 2021;22(5):1268. DOI: https://doi.org/10.3892/etm.2021.10703

Wang X. Obesity, inflammation, and iron metabolism: a systematic review. Nutr Metab (Lond). 2019;16:81. DOI: https://doi.org/10.1186/s12986-019-0367-2

Misra A. Double burden of malnutrition in South Asia: challenges and opportunities. Nutrients. 2019;1112:2767.

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Published

2025-12-30

How to Cite

Bijlwan, A., Rathore, S., Bahrani, J., & Bhargav, N. (2025). Anemia and its determinants among adults in central India: a cross-sectional study. International Journal of Research in Medical Sciences, 14(1), 77–81. https://doi.org/10.18203/2320-6012.ijrms20254362

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Original Research Articles