Assessment of quality of life in patients undergoing maintenance hemodialysis in a tertiary care hospital

Authors

  • Aarnav Goyal Department of Pharmacology, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India https://orcid.org/0009-0003-3177-7648
  • Aarshi Sharma Department of Pharmacology, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India https://orcid.org/0009-0005-2661-5278
  • Pallavi Sharma Department of Nephrology, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India
  • Tamanna Bagal Department of Medicine, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253312

Keywords:

Renal dialysis, Quality of life, Kidney failure, Cross-sectional studies, Hemodialysis

Abstract

Background: The increasing prevalence of end-stage renal disease (ESRD) in India necessitates a deeper understanding of its impact on patient well-being. This study aimed to assess the quality of life (QOL) among hemodialysis (HD) patients in a North Indian setting using the kidney disease QOL-36 (KDQOL-36) instrument and to explore the associated demographic and clinical factors influencing their QOL.

Methods: We conducted an observational, cross-sectional study over two months (May-June 2024) at a tertiary care hospital in Jammu, India. A total of 100 patients aged 18-75 years, diagnosed with ESRD and undergoing maintenance HD for at least three months, were included after providing informed consent. Data was collected using a demographic questionnaire and the validated KDQOL-36 instrument. Statistical analysis was performed using SPSS ver 25.0.

Results: The study cohort comprised 100 patients (66% male) with a mean age of 58.08±12.3 years. The mean QOL scores indicated significant impairment across multiple domains: Physical component summary (PCS) was 41.19±8.24, mental component summary (MCS) was 42.52±7.84, symptom/problem list was 77.75±14.57, and effects of kidney disease was 56.56±16.48. The most profoundly affected domain was the burden of kidney disease, with an exceptionally low mean score of 24.00±15.24. A majority of patients reported that the disease interfered with their life (88%), felt like a burden to their family (74%), and were bothered by fluid (94%) and dietary (88%) restrictions.

Conclusions: This study highlights a profound impairment in the QOL among HD patients in North India, particularly concerning the overwhelming burden of the disease. The findings underscore the urgent need for renal healthcare systems in India to integrate routine QOL assessments into standard practice. Shifting towards a more holistic, patient-centered approach that includes targeted psychosocial support is crucial to alleviate the immense disease burden and improve overall well-being in this vulnerable population.

Metrics

Metrics Loading ...

References

Qazi HA, Chen H, Zhu M. Factors influencing dialysis withdrawal: A scoping review. BMC Nephrol. 2018;19(1):96. DOI: https://doi.org/10.1186/s12882-018-0894-5

Sathvik BS, Parthasarathi G, Narahari MG, Gurudev KC. An assessment of the quality of life in hemodialysis patients using the WHOQOL-BREF questionnaire. Indian J Nephrol. 2008;18(4):141. DOI: https://doi.org/10.4103/0971-4065.45288

Kim S, Nigatu Y, Araya T, Assefa Z, Dereje N. Health related quality of life (HRQOL) of patients with End Stage Kidney Disease (ESKD) on hemodialysis in Addis Ababa, Ethiopia: a cross-sectional study. BMC Nephrol. 2021;22(1):280. DOI: https://doi.org/10.1186/s12882-021-02494-9

Soni RK, Weisbord SD, Unruh ML. Health-related quality of life outcomes in Chronic kidney disease. Curr Opin Nephrol Hypertens. 2010;19(2):153. DOI: https://doi.org/10.1097/MNH.0b013e328335f939

The World Health Organization. WHOQOL-Files| The World Health Organization. Available at: https://www.who.int/tools/whoqol/whoqol-bref. Accessed on 20 July 2025.

Dąbrowska-Bender M, Dykowska G, Żuk W, Milewska M, Staniszewska A. The impact on quality of life of dialysis patients with renal insufficiency. Patient Prefer Adherence. 2018;12:577. DOI: https://doi.org/10.2147/PPA.S156356

Ajeebi A, Saeed A, Aljamaan A, Alshehri M, Nasradeen M, Alharbi N, et al. A study of quality of life among hemodialysis patients and its associated factors using kidney disease quality of life instrument-SF36 in Riyadh, Saudi Arabia. Saudi J Kidney Dis Transpl. 2020;31(6):1225-33. DOI: https://doi.org/10.4103/1319-2442.308331

Jha V. End-stage renal care in developing countries: The India experience. Ren Fail. 2004;26(3):201-8. DOI: https://doi.org/10.1081/JDI-120039516

Cohen DE, Lee A, Sibbel S, Benner D, Brunelli SM, Tentori F. Use of the KDQOL-36TM for assessment of health-related quality of life among dialysis patients in the United States. BMC Nephrol. 2019;20(1):112. DOI: https://doi.org/10.1186/s12882-019-1295-0

Tasnim T, Karim KMR, Rahman T, Rashid HU. Health-related quality of life and its predictors among chronic kidney disease patients: A hospital-based cross-sectional study. PLoS One. 2025;20(2):e0319100. DOI: https://doi.org/10.1371/journal.pone.0319100

Cruz MC, Andrade C, Urrutia M, Draibe S, Nogueira-Martins LA, Sesso R de CC. Quality of life in patients with chronic kidney disease. Clinics. 2011;66(6):991. DOI: https://doi.org/10.1590/S1807-59322011000600012

Bohlke M, Nunes DL, Marini SS, Kitamura C, Andrade M, Von-Gysel MPO. Predictors of quality of life among patients on dialysis in southern Brazil. São Paulo Med J. 2008;126(5):252. DOI: https://doi.org/10.1590/S1516-31802008000500002

Kefale B, Alebachew M, Tadesse Y, Engidawork E. Quality of life and its predictors among patients with chronic kidney disease: A hospital-based cross sectional study. PLoS One. 2019;14(2):e0212184. DOI: https://doi.org/10.1371/journal.pone.0212184

Zimbudzi E, Lo C, Ranasinha S, Gallagher M, Fulcher G, Kerr PG, et al. Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease. PLoS One. 2016;11(12):e0168491. DOI: https://doi.org/10.1371/journal.pone.0168491

Joshi U, Subedi R, Poudel P, Ghimire PR, Panta S, Sigdel MR. Assessment of quality of life in patients undergoing hemodialysis using WHOQOL-BREF questionnaire: a multicenter study. Int J Nephrol Renovasc Dis. 2017;10:195. DOI: https://doi.org/10.2147/IJNRD.S136522

Chiang CK, Peng YS, Chiang SS, Yang CS, He YH, Hung KY, et al. Health-related quality of life of hemodialysis patients in Taiwan: a multicenter study. Blood Purif. 2004;22(6):490-8. DOI: https://doi.org/10.1159/000081730

Wolcott DL, Nissenson AR, Landsverk J. Quality of life in chronic dialysis patients. Factors unrelated to dialysis modality. Gen Hosp Psychiatry. 1988;10(4):267-77. DOI: https://doi.org/10.1016/0163-8343(88)90034-5

Levy NB, Wynbrandt GD. The Quality of Life on Maintenance Haemodialysis. The Lancet. 1975;305(7920):1328-30. DOI: https://doi.org/10.1016/S0140-6736(75)92329-6

Downloads

Published

2025-10-13

How to Cite

Goyal, A., Sharma, A., Sharma, P., & Bagal, T. (2025). Assessment of quality of life in patients undergoing maintenance hemodialysis in a tertiary care hospital. International Journal of Research in Medical Sciences, 13(11), 4634–4640. https://doi.org/10.18203/2320-6012.ijrms20253312

Issue

Section

Original Research Articles