Association of angiographic severity of coronary artery disease and erectile dysfunction based on IIEF-5 score

Authors

  • M. Imam Hosen Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • M. Monir Hossain Khan Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Sujit Kumar Ghosh Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Taslima Binta Belayet Department of Paediatric Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • M. Azharul Islam Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Mohammad Atikur Rahman Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Abdullah-Al-Numan Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Sadia Arju Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • M. Hasan Zaman Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • Tausif Amim Shadly Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253937

Keywords:

Erectile dysfunction, IIEF-5 score, Coronary artery disease, Internal pudendal artery stenosis

Abstract

Background: Erectile dysfunction (ED) is common in patients with coronary artery disease (CAD). Atherosclerosis is a shared mechanism for vasculogenic ED and CAD, suggesting a potential correlation. The objective was to evaluate the association of angiographic severity of coronary artery disease & erectile dysfunction based on IIEF-5 score.

Methods: This cross-sectional study was conducted at NICVD, Dhaka, on 60 patients with CAD and ED. Patients were divided into Group I (Gensini <20, n=30) and Group II (Gensini ≥20, n=30). ED was assessed using the IIEF-5 questionnaire, and IPA angiography was performed in the same setting.

Results: Mean IIEF-5 score was lower in severe CAD (Group II: 13.67±4.17 vs Group I: 15.93±3.14, p=0.021). Significant IPA stenosis (>50%) was more common in Group II (43.3% vs 20%, p=0.042). Spearman’s correlation showed a negative correlation between Gensini and IIEF-5 scores (ρ=-0.475, p=0.01) and a positive correlation with IPA stenosis (ρ=0.410, p=0.03). Logistic regression identified severe CAD (OR 9.13, 95% CI 1.37–60.99) and diabetes mellitus (OR 4.75, 95% CI 1.29–46.33) as predictors of IPA stenosis.

Conclusion: Severity of CAD is inversely associated with erectile function and positively correlated with IPA stenosis.

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References

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Published

2025-11-28

How to Cite

Hosen, M. I., Hossain Khan, M. M., Ghosh, S. K., Belayet, T. B., Islam, M. A., Rahman, M. A., Abdullah-Al-Numan, Arju, S., Zaman, M. H., & Shadly, T. A. (2025). Association of angiographic severity of coronary artery disease and erectile dysfunction based on IIEF-5 score. International Journal of Research in Medical Sciences, 13(12), 5165–5168. https://doi.org/10.18203/2320-6012.ijrms20253937

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Original Research Articles