Role of ultrasonography in the diagnosis of acute appendicitis in emergency cases

Authors

  • Syed Sajad Ahmad Department of Radiology, Government Medical College, Baramulla, J&K, India
  • Asma Gulzar Department of Radiology, Government Medical College, Handwara, J&K, India
  • Huda Amin Department of Gynaecology and Obstetrics, Ramzaan Hospital, Gogji Bagh, Srinagar, J&K, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253388

Keywords:

Ultrasonography, Acute appendicitis, Emergency diagnosis, Histopathological correlation

Abstract

Background: Acute appendicitis remains one of the most common surgical emergencies worldwide, demanding prompt and accurate diagnosis to prevent complications such as perforation or peritonitis. While computed tomography (CT) offers high diagnostic accuracy, ultrasonography (USG) serves as a safer, more accessible alternative, particularly in emergency and resource-limited settings. This study aimed to evaluate the diagnostic accuracy of ultrasonography in acute appendicitis by correlating USG findings with histopathological results among patients presenting with suspected appendicitis in the emergency department.

Methods: A prospective observational study was conducted on 54 patients aged 8–60 years with clinical suspicion of acute appendicitis. All patients underwent graded compression ultrasonography using high-frequency linear and convex probes. Diagnostic parameters including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy were calculated using histopathological findings as the gold standard.

Results: The appendix was visualized in 79.6% of patients. USG diagnosed appendicitis in 41 of 43 positive scans, with 2 false positives and 4 false negatives. The overall diagnostic performance of USG was sensitivity 91.1%, specificity 77.8%, PPV 95.3%, NPV 63.6%, and accuracy 88.9%. Common sonographic findings included a non-compressible tubular structure >6 mm (75.9%), periappendiceal fat stranding (64.8%), and Doppler hyperemia (51.9%). Accuracy was higher in non-obese patients (92.3%) compared to obese individuals (81.8%), and pediatric cases showed superior sensitivity (95%).

Conclusions: Ultrasonography is a reliable, non-invasive, and efficient first-line imaging modality for diagnosing acute appendicitis in emergency settings. It demonstrates high sensitivity and accuracy comparable to CT when performed by skilled radiologists. Incorporating Doppler assessment and adopting a staged USG-CT approach in equivocal cases can further enhance diagnostic confidence while minimizing unnecessary radiation exposure.

 

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References

Puylaert JB. Acute appendicitis: US evaluation using graded compression. Radiology. 1986;158(2):355-60. DOI: https://doi.org/10.1148/radiology.158.2.2934762

Birnbaum BA, Wilson SR. Appendicitis at the millennium. Radiology. 2000;215(2):337-48. DOI: https://doi.org/10.1148/radiology.215.2.r00ma24337

Doria AS, Moineddin R, Kellenberger CJ, Epelman M, Beyene J, Schuh S, et al. US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology. 2006;241(1):83-94. DOI: https://doi.org/10.1148/radiol.2411050913

Terasawa T, Blackmore CC, Bent S, Kohlwes RJ. Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescents. Ann Intern Med. 2004;141(7):537-46. DOI: https://doi.org/10.7326/0003-4819-141-7-200410050-00011

Mathew T, Ammanagi A. Clinicopathological evaluation of acute appendicitis and the role of ultrasound in diagnosis: a prospective study. Int Surg J. 2019;6:1827-32. DOI: https://doi.org/10.18203/2349-2902.isj20191560

van Randen A, Laméris W, van Es HW, van Heesewijk HP, van Ramshorst B, Ten Hove W, et al. OPTIMA Study Group. A comparison of the accuracy of ultrasound and computed tomography in common diagnoses causing acute abdominal pain. Eur Radiol. 2011;21(7):1535-45. DOI: https://doi.org/10.1007/s00330-011-2087-5

Al-Khayal KA, Al-Omran MA. Computed tomography and ultrasonography in the diagnosis of equivocal acute appendicitis: a meta-analysis. Saudi Med J. 2007;28(2):173-80.

Pinto F, Pinto A, Russo A, Coppolino F, Bracale R, Fonio P, et al. Accuracy of ultrasonography in the diagnosis of acute appendicitis in adult patients: review of the literature. Crit Ultrasound J. 2013;5 Suppl 1(Suppl 1):S2. DOI: https://doi.org/10.1186/2036-7902-5-S1-S2

Alelyani M, Hadadi I, Shubayr N, Alashban Y, Alqahtani M, Adam M, et al. Evaluation of ultrasound accuracy in acute appendicitis diagnosis. Appl Sci. 2021;11:2682. DOI: https://doi.org/10.3390/app11062682

Ooms HW, Koumans RK, Ho Kang You PJ, Puylaert JB. Ultrasonography in the diagnosis of acute appendicitis. Br J Surg. 1991;78(3):315-8. DOI: https://doi.org/10.1002/bjs.1800780316

Kessler N, Cyteval C, Gallix B, Lesnik A, Blayac PM, Pujol J, et al. Appendicitis: evaluation of sensitivity, specificity, and predictive values of US, Doppler US, and laboratory findings. Radiology. 2004;230(2):472-8. DOI: https://doi.org/10.1148/radiol.2302021520

Karul M, Berliner C, Keller S, Tsui TY, Yamamura J. Imaging of appendicitis in adults. Rofo. 2014;186(6):551-8. DOI: https://doi.org/10.1055/s-0034-1366074

Hoffmann J, Rasmussen OO. Aids in the diagnosis of acute appendicitis. Br J Surg. 1989;76(8):774-9. DOI: https://doi.org/10.1002/bjs.1800760803

Lee JH, Jeong YK, Park KB, Park JK, Jeong AK, Hwang JC. Operator-dependent techniques for graded compression sonography to detect the appendix and diagnose acute appendicitis. AJR Am J Roentgenol. 2005;184(1):91-7. DOI: https://doi.org/10.2214/ajr.184.1.01840091

Lee JH. Sonography of acute appendicitis. Semin Ultrasound CT MR. 2003;24(2):83-90. DOI: https://doi.org/10.1016/S0887-2171(03)90004-7

Aspelund G, Fingeret A, Gross E, Kessler D, Keung C, Thirumoorthi A, et al. Ultrasonography/MRI versus CT for diagnosing appendicitis. Pediatrics. 2014;133(4):586-93. DOI: https://doi.org/10.1542/peds.2013-2128

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Published

2025-10-24

How to Cite

Ahmad, S. S., Gulzar, A., & Amin, H. (2025). Role of ultrasonography in the diagnosis of acute appendicitis in emergency cases. International Journal of Research in Medical Sciences. https://doi.org/10.18203/2320-6012.ijrms20253388

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Original Research Articles