Fine needle aspiration cytology of breast lumps: how reliable is it? A correlative study with histopathology

Sakshi Agrawal; Sumedh Agrawal; A. S. Gadre; N. V. Dravid

doi:10.18203/2320-6012.ijrms20253966

Authors

Sakshi Agrawal Department of Pathology, ACPM Medical College, Dhule, Maharashtra, India
Sumedh Agrawal Department of Medicine, SBHGMC, Dhule, Maharashtra, India
A. S. Gadre Department of Pathology, ACPM Medical College, Dhule, Maharashtra, India
N. V. Dravid Department of Pathology, ACPM Medical College, Dhule, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20253966

Keywords:

Fine needle aspiration cytology, Breast lumps, Histopathology, FNAC

Abstract

Background: Breast carcinoma is one of the most common malignancies in women. Palpable breast lesions are one of the commonest presentations in general and surgical practice. To study the spectrum of benign and malignant breast lesions and the efficacy of FNAC as a diagnostic tool by correlating with histopathological findings.

Methods: The present study was carried out among 250 patients who presented to ACPM medical college and hospital during a 5-year period from January 2018 to January 2023. All cases that presented with a palpable breast lump were evaluated with FNAC and the lesions were categorised as C1-C5 as per National Health Service Breast screening programme (NHSBSP) reporting criteria. Every patient subjected to FNAC with an adequate result, underwent a definitive surgical procedure. All specimens so obtained were subjected to histopathology. The results thus obtained were matched with those of FNAC and a correlation was sought based on statistical tests. In 243 cases cytohistopathological correlation was obtained.

Results: A total of 250 cases was studied which included 170 benign cases (68%), 52 malignant cases (20.8%), 21 proliferative lesions with atypia (8.4%) and 7 inadequate aspirates (2.8%). The diagnostic accuracy of FNAC in this study was 98.77%.

Conclusions: Aspiration cytology can be done as a first line procedure but cannot be considered as a substitute for histopathology.

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