Spectrum of neurological disorders in children: a 5-year review from a single tertiary hospital in Rivers State, Nigeria
DOI:
https://doi.org/10.18203/2320-6012.ijrms20260592Keywords:
Spectrum, Neurological disorders, Children, Neurology clinic, Port HarcourtAbstract
Background: Neurological disorders in children from developing countries, such as Nigeria, are increasingly varied. Understanding the spectrum of this disorder and having reliable epidemiological data are important for workforce development and instituting preventive modalities to reduce its occurrence. This study aims to examine the patterns and risk factors of neurological disorders among children presenting at the University of Port Harcourt Teaching Hospital (UPTH).
Methods: A descriptive study was conducted among children who attended the consultant paediatric clinic (CPC) from January 2020 to December 2024. A retrospective abstraction of patients’ demographic data and clinical information from their hospital records was done. Statistical package for the social sciences (SPSS) version 25 was used for analysis.
Results: A total of 30,824 children under 18 years attended the CPC over the five years; 6281 (20.4%) had neurological diseases. Of these, 3844 (61.2%) were males, and 2437 (38.8%) were females, giving a male to female ratio of 1.6:1. Epilepsy was the most common neurological disorder, accounting for 2,135 cases (34.0%), followed by central nervous system (CNS) infections with 1765 (28.1%) and cerebral palsy with 1005 (16.0%) cases. The common risk factors were birth asphyxia (40.3%), CNS infections (30.2%), neonatal jaundice (13.3%), and prematurity (6.3%).
Conclusions: The prevalence of neurological disorders is high in our setting; with epilepsy, CNS infections and cerebral palsy as the most common. There is a male preponderance and the risk factors are mostly preventable and requires improving maternal, new-born and child care.
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References
West BA, Aitafo JE. Prevalence and Pattern of Neurological Disorders amongst Children Attending the Neurology Clinic of a Private Paediatric Hospital in Southern Nigeria. Arch Curr Res Int. 2025;25(1):71-8. DOI: https://doi.org/10.9734/acri/2025/v25i11038
Moges A, Gizae S, Zenebe G, Kotagal S. Pattern of Neurological Disorders at Pediatric Outpatient Neurologic Services at Tikur Anbessa Specialized Hospital. Ethiop J Pediatr Child Health. 2018;13(1).
Lagunju IA, Okafor OO. An analysis of disorders seen at the Paediatric Neurology Clinic, University College Hospital, Ibadan, Nigeria. West Afr J Med. 2009;28(1):38-42. DOI: https://doi.org/10.4314/wajm.v28i1.48424
Bower JH, Asmera J, Zebenigus M, Sandroni P, Bower SM, Zenebe G. The burden of inpatient neurologic disease in two Ethiopian hospitals. Neurology. 2007;68(5):338-42. DOI: https://doi.org/10.1212/01.wnl.0000252801.61190.e8
Akodu OS, Ogunlesi TA, Adekanmbi AF, Gbadebo FA. Neurological diseases at the Pediatric Neurology Clinic in a semi-urban Nigerian tertiary hospital. Sudan J Paediatr. 2022;22(1):83-9. DOI: https://doi.org/10.24911/SJP.106-1588669565
Ejeliogu EU, Yiltok ES. Pediatric Neurologic Disorders at a Tertiary Healthcare Facility in North-Central Nigeria: A 5 Year Review. Int. Neuropsy Dis J. 2017;9(4):1-8. DOI: https://doi.org/10.9734/INDJ/2017/35249
Gabriel-Job N, Wobo KN. Profile of paediatric neurologic emergencies at the children emergency ward in a tertiary hospital in Port Harcourt, Nigeria. Int J Contemp Pediatr. 2023;10(8):1176-80. DOI: https://doi.org/10.18203/2349-3291.ijcp20232232
Frank-Briggs AI, Alikor EAD. Pattern of paediatric neurological disorders in Port Harcourt, Nigeria. Int J Biomed Sci. 2011;7(2):145-9. DOI: https://doi.org/10.59566/IJBS.2011.7145
Ibadin MO, Akpede GO. A revised scoring scheme for the classification of socio-economic status in Nigeria. Nigeria J Paediatr. 2021;48(1):26-33. DOI: https://doi.org/10.4314/njp.v48i1.5
World Health Organization. PuLSe Survey on Continuity of Essential Health Services during the COVID-19 Pandemic Global results. 2021. Available at: https://www.who.int/docs/default-source/corona viruse/finalupdate_22-april-2021_summary-ppt_ehs-pulse-survey_second-round.pdf?sfvrsn=a965e121_5. Accessed on 06 December 2025.
Ibrahim A, Ahdi SG, Rafique S, Alvi JR, Waseem A, Sultan T. Spectrum of Neurological Disorders in Children: Frequency, Distribution, Pattern and Related Factors. Pak Pediatr J. 2023;47(1):61-6.
Ogbe Z, Nyarang’o P, Mufunda J. Pattern of neurological diseases as seen in outpatient children: the experiences from Orotta Referral Hospital Asmara, Eritrea. J Eritrean Med Assoc. 2010;12(1):11-5. DOI: https://doi.org/10.4314/jema.v1i1.52634
Ifezulike CC, Okeke KN, Onubogu CU, Echendu ST, Odita AO, Agu NV, et al. Pattern of Neurological Disorders among Children Presenting at the Neurology Unit of Tertiary Hospital in Awka. Open J Endocrine Metab Dis. 2023;13:53-62. DOI: https://doi.org/10.4236/ojemd.2023.134006
Gandhi MK, Raina SK, Bhardwaj A, Sood A. Prevalence of major neurological disorders in predominantly rural northwest India. J Family Med Prim Care. 2020;9:4627 32. DOI: https://doi.org/10.4103/jfmpc.jfmpc_1048_19
American Migraine Foundation. Spotlight on: Migraine in Women | AMF. American Migraine Foundation. 2022. Available at: https://american migrainefoundation.org/resource-library/migraine-women/d. Accessed on 06 December 2025
Leijser LM, Siddiqi A, Miller SP. Imaging Evidence of the Effect of Socio-Economic Status on Brain Structure and Development. Semin Pediatr Neurol. 2018;27:26-34. DOI: https://doi.org/10.1016/j.spen.2018.03.004
Lawal H, Anyebe EE, Obiako OR, Garba SN. Socio-economic challenges of parents of children with neurological disorders: A hospital-based study in North West Nigeria. Int J Nurs Midwifery. 2014;6(4):58-66. DOI: https://doi.org/10.5897/IJNM2014.0122
Gabriel-Job N, Udofia EA, Akani NA. Harmful Traditional Practices among Adolescents: Knowledge, Perception and Complications. The Nig Health J. 2023;22(4):433-9.
Darwish SY, Ammar MA, Gad HK, El Ghrieb HA, El-Din TM, Ahmed M. Pattern of Paediatrics Neurological Disorders in Paediatric Neurology Unit of Al-Azher University Hospitals in Egypt. Natur Sci. 2015;13:139-44.
Mohammed IN, Elseed MA, Hamed AA. Clinical Profile of Paedia trics Neurological Disorders: Outpatient Department, Khartoum, Sudan. Child Neurol Open. 2015;3:1-5. DOI: https://doi.org/10.1177/2329048X15623548
Kumar R, Bhave A, Bhargava R, Agarwal GG. Prevalence and risk factors for neurological disorders in children aged 6 months to 2 years in northern India. Dev Med Child Neurol. 2013;55(4):348-56. DOI: https://doi.org/10.1111/dmcn.12079
DeMyer W. Normal and Abnormal Development of the Neur axis. In: Rudolph CD, Rudolph AM, Hostetter MK, Lister G, Siegel NJ, Eds. Rudolph’s Paediatrics. New York: Mc Graw Hill. 2003: 2174-2178.