Physical fitness in Belarusian children with chronic gastritis
DOI:
https://doi.org/10.18203/2320-6012.ijrms20260937Keywords:
Chronic gastritis, Belarusian children, Physical fitness, Relationship, Height-for-age, BMI-for-ageAbstract
Background: Chronic gastritis is a common pediatric condition characterized by inflammation of the gastric mucosa. Its potential impact on children’s growth and physical development remains underexplored. This study aimed to assess the relationship between chronic gastritis and physical development in Belarusian children, focusing on height and body mass index (BMI) compared to WHO growth standards.
Methods: A retrospective cross-sectional review was conducted on 100 pediatric patients diagnosed with chronic gastritis in 2023 at Grodno Regional Clinical Pediatric Hospital, Belarus. Growth indicators were analyzed using AnthroPlus software, with Z scores for height-for-age and BMI-for-age calculated and compared against WHO reference values.
Results: Among the 100 children (76% female, mean age 13 years), height-for-age z-scores demonstrated a rightward shift, indicating taller stature compared to WHO standards. Conversely, BMI-for-age z-scores showed a leftward shift, reflecting lower BMI values. This disproportionate growth pattern tall stature with lean body composition was more pronounced in girls and persisted across age groups, particularly in middle and high school children.
Conclusions: Chronic gastritis in children appears to negatively influence physical development by reducing BMI, despite an unexpected trend toward increased height. These findings highlight the importance of monitoring growth trajectories and addressing nutritional and metabolic factors in pediatric patients with chronic gastritis. Further multi-center studies are needed to validate these results and clarify underlying mechanisms.
Metrics
References
Sipponen P, Maaroos HI. Chronic gastritis. Scand J Gastroenterol. 2015;50(6):657-7. DOI: https://doi.org/10.3109/00365521.2015.1019918
Andriyani R, Fadlyana E, Tarigan R. Factors affecting the developmental status of children aged 6 months to 2 years in urban and rural areas. Children. 2023;10(7):1214. DOI: https://doi.org/10.3390/children10071214
Josyabhatla R, Wood ML, Gafur A, Tatevian N, Tchakarov AS, Hashmi SS, et al. Rising prevalence of mild chronic gastritis in children: a single center experience. Pediatr Developm Pathol. 2024;27(3):235-40. DOI: https://doi.org/10.1177/10935266241238625
Taietti I, Votto M, Castagnoli R, Bertozzi M, De Filippo M, Di Sabatino A, et al. Clinical heterogeneity of early-onset autoimmune gastritis: from the evidence to a pediatric tailored algorithm. Dis. 2025;13(5):133. DOI: https://doi.org/10.3390/diseases13050133
Gu S, Li D, Sun J, Liu J, Mao K. Expression and analysis of NLRP6 in chronic gastritis in children. BMC Gastroenterol. 2025;25(1):829. DOI: https://doi.org/10.1186/s12876-025-04435-4
Perrin EC, Gerrity PS. Development of children with a chronic illness. Pediatr Clin North Am. 1984;31(1):19-31. DOI: https://doi.org/10.1016/S0031-3955(16)34533-3
Xu C, Wu Y, Xu S. Association between Helicobacter pylori infection and growth outcomes in children: A meta‐analysis. Helicobacter. 2022;27(1). DOI: https://doi.org/10.1111/hel.12861
Bravo LE, Mera R, Reina JC, Pradilla A, Alzate A, Fontham E, et al. Impact of Helicobacter pylori infection on growth of children: a prospective cohort study. J Pediatr Gastroenterol Nutr. 2003;37(5):614-9. DOI: https://doi.org/10.1002/j.1536-4801.2003.tb12073.x
Goodman KJ, Correa P, Tenganá Aux HJ, DeLany JP, Collazos T. Nutritional factors and helicobacter pylori infection in colombian children. J Pedia Gastroenterol amp Nutrit. 1997;25(5):507-15. DOI: https://doi.org/10.1002/j.1536-4801.1997.tb00703.x
Hershko C, Patz J, Ronson A. The anemia of achylia gastrica revisited. Blood Cells Mol Dis. 2007;39(2):178-83. DOI: https://doi.org/10.1016/j.bcmd.2007.03.006
Franceschi F. Role of Helicobacter pylori infection on nutrition and metabolism. World J Gastroenterol. 2014;20(36):12809. DOI: https://doi.org/10.3748/wjg.v20.i36.12809
Koletzko S, Jones NL, Goodman KJ, Gold B, Rowland M, Cadranel S, et al. Evidence‐based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children. J Pediatr Gastroenterol Nutr. 2011;53(2):230-43. DOI: https://doi.org/10.1097/MPG.0b013e3182227e90
Grasgruber P, Mašanović B, Prce S, Popović S, Arifi F, Bjelica D, et al. Mapping the mountains of giants: anthropometric data from the western Balkans Reveal a nucleus of extraordinary physical stature in Europe. Biology (Basel). 2022;11(5):786. DOI: https://doi.org/10.3390/biology11050786
Soylu OB, Ozturk Y. Helicobacter pylori infection: effect on malnutrition and growth failure in dyspeptic children. Eur J Pediatr. 2008;167(5):557-62. DOI: https://doi.org/10.1007/s00431-007-0552-6
Benavides-Ward A, Vasquez-Achaya F, Silva-Caso W, Aguilar-Luis MA, Mazulis F, Urteaga N, et al. Helicobacter pylori and its relationship with variations of gut microbiota in asymptomatic children between 6 and 12 years. BMC Res Notes. 2018;11(1):468. DOI: https://doi.org/10.1186/s13104-018-3565-5
Kotilea K, Kalach N, Homan M, Bontems P. Helicobacter pylori infection in pediatric patients: update on diagnosis and eradication strategies. Pediatric Drugs. 2018;20(4):337-51. DOI: https://doi.org/10.1007/s40272-018-0296-y
Zuo N ying, Zhang Y da, Dong Q wei, Bi J, Liu X. Effect of Anti-Hp treatment on nutritional status of children with Helicobacter Pylori-Positive Gastritis and its clinical significance. Pak J Med Sci. 2021;37(5). DOI: https://doi.org/10.12669/pjms.37.5.4234
Mohamed NF, Behairy OGA, EL-Defrawy MS, Elsayed MM, Alhusseini NF. Role of miRNA-146a and miRNA-125b in Helicobacter pylori. Clin Exp Pediatr. 2025;68(10):781-9. DOI: https://doi.org/10.3345/cep.2025.00192
Griffiths AM. Growth retardation in early-onset inflammatory bowel disease: should we monitor and treat these patients differently? Digest Dis. 2009;27(3):404-11. DOI: https://doi.org/10.1159/000228581
Parent AS, Teilmann G, Juul A, Skakkebaek NE, Toppari J, Bourguignon JP. The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration. Endocr Rev. 2003;24(5):668-93. DOI: https://doi.org/10.1210/er.2002-0019
Brown LM, Clegg DJ. Central effects of estradiol in the regulation of food intake, body weight, and adiposity. J Steroid Biochem Mol Biol. 2010;122(1-3):65-73. DOI: https://doi.org/10.1016/j.jsbmb.2009.12.005
Lewis ML, Palsson OS, Whitehead WE, van Tilburg MAL. Prevalence of functional gastrointestinal disorders in children and adolescents. J Pediatr. 2016;177:39-43.e3. DOI: https://doi.org/10.1016/j.jpeds.2016.04.008