Unusual case of recurrent bony pain and swelling in a child: a case report
DOI:
https://doi.org/10.18203/2320-6012.ijrms20261718Keywords:
Pyrexia of unknown origin, Arthritis, CRMO, TuberculosisAbstract
Prolonged fever in children is a vexing problem. High grade fever with multiple joint pain and swelling can be seen in infections, inflammatory conditions, connective tissue disorders and malignancies. Peri articular pain and fever can be seen in enthesitis, osteomyelitis and malignancy whereas articular pain can be seen in hereditary arthropathies, infectious and inflammatory conditions. Arthritis is defined as presence of pain, swelling, rednness, warmth and diminished range of motion. Involvement of more than four joints is taken as polyarthritis. Tuberculosis is an important differential diagnosis in this situation. Here we present a case of a 11-year-old boy with complaints of prolonged fever of 5 months duration with progressive pain, swelling and restriction of mobility of multiple joints. Investigations to rule out inflammatory arthritis, malignancy and infections were done in this child which were initially not pointing to a specific diagnosis. At times, even after best efforts, microbiological diagnosis cannot be established and we have to resort to advanced imaging, techniques and rely on a constellation of clinical and radiological, cytological and microbiological clues to clinch the diagnosis.
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References
Didel S, Purohit A, VyasV, Kumar P. Disseminated tuberculosis in children—a difficult diagnose depends on how far we can go. BMJ Case Rep. 2020;13(12):e237192. DOI: https://doi.org/10.1136/bcr-2020-237192
Vohra R, Kang HS, Dogra S, Sagaar RR, Sharma R. Tuberculous Osteomyelitis. J Bone Joint Surg BR. 1997;79(4):562-6. DOI: https://doi.org/10.1302/0301-620X.79B4.0790562
Hosalkar HS, Agrawal N, Reddy S, Sehgal K, Fox EJ, Hill RA. Skeletal tuberculosis in children in the Western world: 18 new cases with a review of the literature. J Child Orthop. 2009;3:319-24. DOI: https://doi.org/10.1007/s11832-009-0184-7
Teo HE, Peh WC. Skeletal tuberculosis in children. Pediatr Radiol. 2004;34:853-60.
Lee KY. Comparison of Pyogenic Spondylitis and Tuberculous Spondylitis. Asian Spine J. 2014;8:216-23. DOI: https://doi.org/10.4184/asj.2014.8.2.216
Eisen S, Honywood L, Shingadia D, Novelli V. Spinal tuberculosis in children. Arch Dis Child. 2012;97:724-9. DOI: https://doi.org/10.1136/archdischild-2011-301571
Moon MS, Kim SS, Lee BJ, Moon JL. Spinal tuberculosis in children: Retrospective analysis of 124 patients. Indian J Orthop. 2012;46:150-8. DOI: https://doi.org/10.4103/0019-5413.93676
Seung OP, Sulaiman W. Osteoarticular tuberculosis mimicking rheumatoid arthritis. Mod Rheumatol. 2012;22:931-3. DOI: https://doi.org/10.1007/s10165-012-0605-1
Ruggieri M, Pavone V, Polizzi A, Smilari P, Di Fede GF, Sorge G, et al. Clin Pediatr. 1997;36(9):529-34. DOI: https://doi.org/10.1177/000992289703600906
Rasool MN. Osseous manifestations of tuberculosis in children. J Pediatr Orthop. 2001;21:749-55. DOI: https://doi.org/10.1097/01241398-200111000-00009
Teo HE, Peh WC. Skeletal tuberculosis in children. Pediatr Radiol. 2004;34:853-60. DOI: https://doi.org/10.1007/s00247-004-1223-7
Agarwal A, Kant KS, Suri T, Gupta N, Verma I, Shaharyar A. Tuberculosis of the calcaneus in children. J Orthop Surg (Hong Kong). 2015;23:84-9. DOI: https://doi.org/10.1177/230949901502300120
Geslani MB, Laya BF. TB of the Skeletal System in Children: Spectrum of Imaging Findings. St. Luke’s J Med. 2011;7:51-8.
Agarwal A. Paediatric osteoarticular tuberculosis: A review. J Clin Orthop Trauma. 2020;11(2):202-7. DOI: https://doi.org/10.1016/j.jcot.2020.01.005
Chaudhuri AD. Recent changes in technical and operational guidelines for tuberculosis control programme in India - 2016: a paradigm shift in tuberculosis control. J Assoc Chest Physicians. 2017;5:1-9. DOI: https://doi.org/10.4103/2320-8775.196644
Hu X, Zhang H, Yin X, Chen Y, Yu H, Zhou Z. One-stage posterior focus debridement, fusion, and instrumentation in the surgical treatment of lumbar spinal tuberculosis with kyphosis in children. Childs Nerv Syst. 2016;32:535-9. DOI: https://doi.org/10.1007/s00381-015-2948-3