Stem cell therapy for sensorineural hearing loss: A narrative review
DOI:
https://doi.org/10.18203/2320-6012.ijrms20261375Keywords:
Sensorineural hearing loss, Stem cell therapy, Neural stem cells, CochleaAbstract
Transplanting neural stem cells has drawn a lot of interest as a novel therapeutic approach for replacing specific cells that have been harmed by disorders like neurodegenerative diseases. Neural stem cell transplantation has a significant therapeutic impact on cell activation and regeneration as well as the restoration of damaged neurons in many organs. As stem cell research advances, stem cell therapy will become more important in treating inner ear diseases including sensorineural hearing loss. The invasive surgical procedure may result in severe hearing loss because of the unique structure of the cochlea. Therefore, several methods are chosen for neural stem cell implantation depending on the conditions and goals of the treatment. The methods for stimulating endogenous and exogenous stem cell differentiation in the inner ear are discussed in this review article. Although stem cell therapy still has many drawbacks, its potential to treat hearing loss has been widely acknowledged. This review attempts to provide a thorough overview of stem cell therapy for sensorineural hearing loss (SNHL), the difficulties encountered, and possible future prospects in this field by combining recent research and innovation.
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