Axillary primary mucin producing epithelial malignancy - rarely encountered site

Authors

  • Kalyani Dnyaneshwar Aher Department of General Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India
  • Minakshi Gadahire Department of General Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20261711

Keywords:

Axilla, IHC markers, Metastatic mucin producing carcinoma, Primary mucin producing carcinoma, Rare site

Abstract

The most common skin malignancy in the axilla is Basal cell carcinoma. Primary mucin producing epithelial carcinoma in the axilla can closely resemble metastatic mucinous carcinoma, most often originating from the breast, but also from the gastrointestinal tract, lung or ovary. Axilla is a rare site for primary mucin-producing epithelial carcinoma of skin. Thorough clinical examination histopathological examination with IHC and other ancillary investigations are necessary to confirm the diagnosis and to rule out metastatic mucinous carcinoma. We present a rare case of primary mucin producing epithelial carcinoma of axillary skin in an elderly male patient which was present since two and half year, without any complication. Which was diagnosed by histopathological examination, complete clinical examination and radiological examination and confirmed with IHC marker. Which presented to us as a lesion mimicking benign cyst. Which was managed by wide local excision of the lesion and lymph node dissection till level II.

References

Bari V, Poshirkar A. Cutaneous primary mucinous adenocarcinoma of axilla – a rare tumour at rare site. Int J Curr Med Appl Sci. 2015;9:7-9.

Kotru M, Manucha V, Singh UR. Cytologic and histologic features of primary mucinous adenocarcinoma of skin in the axilla: a case report. Acta Cytol. 2007;51:571-4.

Martinez S, Young S. Primary mucinous carcinoma of the skin: a review. Internet J Oncol. 2004;2:1-7.

Maerki J, Ahmed S, Lee E. Primary mucinous carcinoma of the skin. ePlasty. 2013;13:ic47.

Lennox B, Pearse AE, Richards HG. Mucin-secreting tumours of the skin: with special reference to the so-called mixed-salivary tumour of the skin and its relation to hidradenoma. J Pathol Bacteriol. 1952;64:865-80.

Adefusika JA, Pimentel JD, Chavan RN, Brewer JD. Primary mucinous carcinoma of the skin: the Mayo Clinic experience over the past 2 decades. Dermatol Surg. 2015;41:201-8.

Hemalatha AL, Kausalya SK, Amita K, Sanjay M, Lavanya MS. Primary mucinous eccrine adenocarcinoma – a rare malignant cutaneous adnexal neoplasm at an unconventional site. J Clin Diagn Res. 2014;8:FD14-5.

Snow SN, Reizner GT. Mucinous eccrine carcinoma of the eyelid. Cancer. 1992;70(8):2099-104.

Bellezza G, Sidoni A, Bucciarelli E. Primary mucinous carcinoma of the skin. Am J Dermatopathol. 2000;22(2):166-9.

Kazakov DV, Suster S, LeBoit PE, Calonje E, Bisceglia M, Kutzner H, et al. Mucinous carcinoma of the skin, primary, and secondary: a clinicopathologic study of 63 cases with emphasis on the morphologic spectrum of primary cutaneous forms: homologies with mucinous lesions in the breast. Am J Surg Pathol. 2005;29:764-82.

Downloads

Published

2026-05-29

How to Cite

Aher, K. D., & Gadahire, M. (2026). Axillary primary mucin producing epithelial malignancy - rarely encountered site. International Journal of Research in Medical Sciences, 14(6), 2608–2611. https://doi.org/10.18203/2320-6012.ijrms20261711

Issue

Section

Case Reports