From clinical complaints to radiological revelation: case study of cecal adenocarcinoma with multiorgan involvement
DOI:
https://doi.org/10.18203/2320-6012.ijrms20261709Keywords:
Cecal adenocarcinoma, Chronic intestinal obstruction, Late presentation, Multidisciplinary approach, Right-sided colon cancer, Diagnostic imaging, MetastasisAbstract
Colorectal cancer (CRC) is the third most common malignancy in the world, with adenocarcinoma accounting for the vast majority of cases. A 60-year-old male complained about the presence of a tumour like palpable mass in the right iliac region with general weakness and weight loss. Patient was eventually transferred to the oncology department for further investigations and treatment. Initial colonoscopy evaluations combined with the anatomical difficulty of visualizing the cecum. A barium enema demonstrated narrowing at the cecum, suggestive of obstruction. Radiological imaging proved decisive in this case, revealing the full extent of local invasion and distant metastasis. Histopathological and cytological findings established the diagnosis of metastatic adenocarcinoma. This case underscores the diagnostic and therapeutic challenges associated with right‑sided colorectal cancers with late presentation, particularly cecal adenocarcinoma, which progress silently until an advanced stage. This case illustrates the importance of multi-disciplinary approach in oncology involving internal medicine for timely diagnosis and treatment.
References
Gaillard F, Sharma R, Walizai T. Colorectal cancer. 2008.
Jing Y, Li C, Du T, Jiang T, Sun H, Yang J, et al. A comprehensive survey of intestine histopathological image analysis using machine vision approaches. Comput Biol Med. 2023;165:107388.
Song S, Wang J, Zhou H, Wang W, Kong D. Poorer survival in patients with cecum cancer compared with sigmoid colon cancer. Medicina (Kaunas). 2022;59(1):45.
Xie X, Zhou Z, Song Y, Wang W, Dang C, Zhang H. Differences between carcinoma of the cecum and ascending colon: evidence based on clinical and embryological data. Int J Oncol. 2018;52:1581-9.
Nakagawa-Senda H, Hori M, Matsuda T, Ito H. Prognostic impact of tumor location in colon cancer: the Monitoring of Cancer Incidence in Japan (MCIJ) project. BMC Cancer. 2019;19(1):431.
Menon G, Cagir B. Colon cancer. In: StatPearls. Treasure Island (FL): StatPearls Publishing. 2024.
AlSulaiman IA, Sallah M, Khouqeer GA, Rusu-Both R, Abdelrazek EM, Elgarayhi A. Enhanced automatic diagnosis of cecum colorectal cancer using novel artificial neural network on abdominal CT radiological scans. J Radiat Res Appl Sci. 2025 Jun;18(2):101358. doi:10.1016/j.jrras.2025.101358
Qaseem A, Fitterman N, Tierney S, Powell RE, Campos K, Choi EI, et al. Identifying core clinical topics and recommending core performance measures for internal medicine physicians: A position paper from the American College of Physicians. Ann Intern Med. 2025;178(11):1616-23.
Jørgensen SF, Ravn P, Thorsen S, Worm SW. Characteristics and outcome in patients with non-specific symptoms and signs of cancer referred to a fast-track cancer patient pathway: a retrospective cohort study. BMC Cancer. 2017;17:809.
Kwan JL, Singh H. General internists in pursuit of diagnostic excellence in primary care: a #ProudtobeGIM thread that unites us all. J Gen Intern Med. 2018;33(4):395-6.
Drozdinsky G, Halperin E, Kushnir S, Rudman Y, Gafter-Gvili A. The utility of inpatient work-up of incidental anemia during hospitalization for an acute medical condition: a retrospective cohort study. Am J Med Sci. 2025;369(6):712-8.
Orr L, Forbes V. Colon cancer masquerading as a CHF exacerbation. Am J Gastroenterol. 2016;111:S1322.
Santos-Silva MA, Sousa N, Majar M, Machado M, Reis J, Sousa JC. Pattern recognition of hematological profiles of tumors of the digestive tract: an exploratory study. Front Med (Lausanne). 2023;10:1208022.
Scientific abstracts. J Gen Intern Med. 2018;33(2):S83-40.
Ali A, Naeem S, Anam S, Ahmed MM. Current state of artificial intelligence (AI) in oncology: a review. Curr Trends Omics. 2023;3(1):1-17.
Jha AK, Mithun S, Sherkhane UB, Dwivedi P, Puts S, Osong B, et al. Emerging role of quantitative imaging (radiomics) and artificial intelligence in precision oncology. Explor Target Antitumor Ther. 2023;4:569-82.
Eigeliene N, Saarenheimo J, Wichmann V, Österlund P, Jekunen A. Metastatic rectal carcinoma with long-term remission due to modern multimodality treatment. Case Rep Oncol. 2021;14(3):1475-82.
Wang J, Chen P, He C, Niu X, Li L. A case of diffuse colorectal cancer. Research Square. 2024.
Marzano M, Prosperi P, Grazi GL, Cianchi F, Talamucci L, Bisogni D, et al. Upfront surgery vs. endoscopic stenting bridge to minimally invasive surgery for treatment of obstructive left colon cancer: analysis of surgical and oncological outcomes. Cancers (Basel). 2024;16(23):3895.
Mikalonis M, Avlund TH, Løve US. Danish guidelines for treating acute colonic obstruction caused by colorectal cancer—a review. Front Surg. 2024;11:1400814.
Constantin VD, Silaghi A, Epistatu D, Dumitriu AS, Paunica S, Bălan DG, et al. Diagnosis and management of colon cancer patients presenting in advanced stages of complications. J Mind Med Sci. 2023;10(1):51-65.