Correlation between serum ferritin and glycaemic control in patients of type 2 diabetes mellitus: a case control study


  • Amitkumar Virji Maheshwari Department of Biochemistry, Gujarat Adani Institute of Medical Sciences, Bhuj, Gujarat
  • Bharat K. Bhoi Department of Biochemistry, Government Medical College, Bhavnagar, Gujarat
  • Bhavesh R. Sadariya Department of Biochemistry, Pacific Medical College, Udaipur, Rajasthan
  • Hardik N. Javia Department of Biochemistry, C. U Shah Medical College, Surendranagar, Gujarat
  • Jigar K. Gusani Department of Microbiology, Gujarat Adani Institute of Medical Sciences, Bhuj, Gujarat
  • Hariom Sharma Department of Biochemistry, Government Medical College, Bhavnagar, Gujarat



Type 2 diabetes mellitus, Ferritin, HbA1c


Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Ferritin is a ubiquitous intracellular protein complex that reflectes the iron stores of the body. Many cross-sectional studies indicate that increased body iron stores have been associated with the development of glucose intolerance, type 2 diabetes, metabolic syndrome. This study was carried out to find out the relationship between serum ferritin and type 2 diabetes and to see the influence of body iron stores on HbA1c and blood glucose.

Methods: This study includes 50 patients suffering from type 2 diabetes and compared with controls at Sir T hospital, Bhavnagar. S. ferritin, Fasting Blood Sugar (FBS), Post Prandial Blood Sugar (PPBS) and HbA1c were measured.

Results: Serum ferritin was significantly higher (p<0.0001) in the patients suffering from type 2 diabetes and the correlation between serum ferritin and HbA1c was positive. Patients with type 2 diabetes with increased level of serum ferritin had poor glycemic control reflected by increased levels of HBA1c (r=0.701, p<0.0001)

Conclusions: There is a positive association between elevated iron stores measured by serum ferritin levels and type 2 diabetes mellitus. Ferritin levels also correlated FBS, PP2BS and HbA1c.



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How to Cite

Maheshwari, A. V., Bhoi, B. K., Sadariya, B. R., Javia, H. N., Gusani, J. K., & Sharma, H. (2017). Correlation between serum ferritin and glycaemic control in patients of type 2 diabetes mellitus: a case control study. International Journal of Research in Medical Sciences, 3(9), 2327–2330.



Original Research Articles