Comparison between rapid urease test and carbon 14 urea breath test in the diagnosis of Helicobacter pylori infection

Authors

  • Harmeet Sahni Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Karishma Palshetkar Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Tanveer Parvez Shaikh Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Sharique Ansari Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Mithilesh Ghosalkar Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Aditya Oak Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra
  • Naseem Khan Department of Surgery, DY Patil College of Medicine, Nerul, Navi Mumbai, Maharashtra

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150632

Keywords:

Rapid urease test, Carbon 14 urea breath test, Helicobacter pylori, Peptic ulcer

Abstract

Background: The most common human infection of upper gastrointestinal region is Helicobacter pylori. Most individuals remain asymptomatic due to misuse of antibiotic and proton pump inhibitors.  

Methods: 50 patients admitted or on outpatient department basis were selected based on the upper gastrointestinal symptoms and whether they were 18 years and above.

Results: The Rapid Urease Test (RUT) had 84% sensitivity and 91% specificity, with an overall accuracy of 88%. The results of the Urea breath Test (UBT) showed 88% sensitivity and 83% specificity, and an overall accuracy of 85%.

Conclusions: The invasive procedure OGD scopy need not be done in patients for the sole purpose of diagnosing HP infection as the diagnostic efficacies of RUT & UBT tests are similar.

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Published

2017-01-12

How to Cite

Sahni, H., Palshetkar, K., Shaikh, T. P., Ansari, S., Ghosalkar, M., Oak, A., & Khan, N. (2017). Comparison between rapid urease test and carbon 14 urea breath test in the diagnosis of Helicobacter pylori infection. International Journal of Research in Medical Sciences, 3(9), 2362–2365. https://doi.org/10.18203/2320-6012.ijrms20150632

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Original Research Articles